Submited on: 23 Aug 2012 04:41:46 PM GMT
Published on: 24 Aug 2012 02:32:56 PM GMT
review comment
Posted by Dr. Sameeh S Ghazal on 26 Aug 2012 08:16:17 AM GMT

Thank you for referring this article (Helicobacter Pylori Infection in Children

) for me for reviewing:

 

It is nice review anyhow, but I could notice the followings:

  • Author should observe the ward (children) in his title and do his best to describe the disease in children mainly, we could observe that this has been forgotten in describing the prevalence of the disease and disease complications like cancer which is mainly adult issue.
  • Author did not mention the relation between helicobacter, cytokines associated antigen, high or low production of acids, getting higher incidence of cancer or ulcer.
  • Author did not mention clearly mode of transmission and its reference
  • Author did not clarify if there is one or more than one pathogenesis in relation to cancer or ulcer complications?
    • Author did not mentioned in the diagnosis section the indications of testing for H pylori as recommended by the recent guidelines from North European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) and North American Society for Paediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) for H pylori infection in children

Author did not mention a list for the Differential Diagnoses?

  • competing interests: None
  • Invited by the author to make a review on this article? :
  • Experience and credentials in the specific area of science: None
  • Publications in the same or a related area of science: No
  • References: None
 
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Dear Dr. Sameeh Ghazal, Thanks for taking time to review and comment on my article. The points are well taken and will be incorporated in the revised version of the ms TQ Best rgds Dr. Shahid SK.
Responded by Dr. Sukhbir Shahid on 26 Aug 2012 08:30:09 AM

IT IS INFORMATIC FOR THE COMMON PEOPLE,IT IS SUGGESTED THAT BEFORE GOING FOR THE HUMAN TRIAL ,MAMMALIAN MODEL MAY BE DESIGNED

  • Invited by the author to make a review on this article? :
  • Experience and credentials in the specific area of science: None
  • Publications in the same or a related area of science: No
  • References: None
 
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Dear Dr. Rajan, Thanks for your comments. Points are noted and will be included in revised version of ms TQ Best rgds Dr. Shahid S.
Responded by Dr. Sukhbir Shahid on 26 Aug 2012 08:32:35 AM