Submited on: 14 Dec 2011 07:13:10 AM GMT
Published on: 14 Dec 2011 08:49:27 AM GMT
 

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    need rearrengments of references

    need in vivo study

    open a new scope for antibacterial action of H2-blockers

  • Competing interests:
    no
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    no

  • How to cite:  Xan G .In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study [Review of the article 'In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study ' by Alkuraishy H].WebmedCentral 2012;3(2):WMCRW001512
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1 Is the subject of the article within the scope of the subject category? Partly
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? Yes
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    interpretations of significant level should depend the p value

  • Competing interests:
    no
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    yes

  • How to cite:  Ntyloor G .In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study[Review of the article 'In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study ' by Alkuraishy H].WebmedCentral 2012;3(1):WMCRW001436
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    justified paper

  • Competing interests:
    no
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    Yes
  • References:
    None
  • Experience and credentials in the specific area of science:

    yes

  • How to cite:  Keen F .In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study[Review of the article 'In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study ' by Alkuraishy H].WebmedCentral 2012;3(1):WMCRW001435
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    good new idea

  • Competing interests:
    no
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    yes

  • How to cite:  Tylor H .In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study[Review of the article 'In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study ' by Alkuraishy H].WebmedCentral 2012;3(1):WMCRW001432
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Partly
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    acceptable

  • Competing interests:
    no
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    yes

  • How to cite:  Juvaniae Q .In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study[Review of the article 'In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study ' by Alkuraishy H].WebmedCentral 2012;3(1):WMCRW001402
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    informative and applicable

  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    Yes
  • References:
    None
  • Experience and credentials in the specific area of science:

    yes

  • How to cite:  Xan G .In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study[Review of the article 'In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study ' by Alkuraishy H].WebmedCentral 2012;3(1):WMCRW001401
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Partly
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    good

  • Competing interests:
    no
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    yes

  • How to cite:  Zusoor N B.In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study[Review of the article 'In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study ' by Alkuraishy H].WebmedCentral 2012;3(1):WMCRW001390
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    original

  • Competing interests:
    no
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    yes

  • How to cite:  Hadi S .In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study[Review of the article 'In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study ' by Alkuraishy H].WebmedCentral 2012;3(1):WMCRW001389
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    need i vivo study

  • Competing interests:
    no
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    yes

  • How to cite:  Hood L .In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study[Review of the article 'In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study ' by Alkuraishy H].WebmedCentral 2012;3(1):WMCRW001388
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    rearrangment of references

  • Competing interests:
    no
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    yes

  • How to cite:  Nasir M .In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study[Review of the article 'In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study ' by Alkuraishy H].WebmedCentral 2012;3(1):WMCRW001387
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Partly
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? No
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

     i so appreciate this work

  • Competing interests:
    no
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    yes

  • How to cite:  Grestong R .In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study[Review of the article 'In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study ' by Alkuraishy H].WebmedCentral 2012;3(1):WMCRW001386
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    satisfactory article

  • Competing interests:
    no
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    yes

  • How to cite:  Butty C .In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study[Review of the article 'In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study ' by Alkuraishy H].WebmedCentral 2012;3(1):WMCRW001385
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    good article

  • Competing interests:
    no
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    yes

  • How to cite:  Zas K .In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study[Review of the article 'In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study ' by Alkuraishy H].WebmedCentral 2012;3(1):WMCRW001384
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Partly
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? Yes
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? No
9 Are the illustrations and tables necessary and acceptable? No
10 Are the references adequate and are they all necessary? No
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    The paper is focused on the actual problem of searching of new antibacterial drugs that are no antibiotics. Author shows that the Famotidine, that is antihistamine receptor type 2 blocker, has significant antibacterial activity,  specially against Escherichia coli. Unfortunately, this valuable finding is presented in unsatisfactory form, that give rise to many criticism, particularly:

    1) The tables should be revised and show statistics, at least mean ± SD and P compared to negative controls, because each bacterial group is presented by several strains. Alternatively, every bacterial strain may be showed individually.

    2) Acronyms in tables should be explained (Table 3: MIC?)

    3) Unclear, what concentrations test compounds (cimetidine, ranitidine and famotidine) are contained in 100 ml (Section of Methods and Tables 2, 3).

    4) All tables should be revised concerning mistakes and presented in more acceptable form.

    5) Figure 1 should be presented in more acceptable form.

    6) The all text need to revise on clarity, conciseness and correctness of language.

    7) List of references should be presented in uniform manner and updated with articles 2008-2011.

     

    Thus, the manuscript should be significantly revised and resubmitted.

  • Competing interests:
    No
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    No

  • How to cite:  Shichkin V .In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study [Review of the article 'In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study ' by Alkuraishy H].WebmedCentral 2012;2(12):WMCRW001277
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? Yes
7 Can you suggest any reductions in the paper, or deletions of parts? Yes
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    good article

  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    yes

  • How to cite:  Mohamed H .In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study[Review of the article 'In Vitro Antibacterial Effects Of Selective Histaminic Receptor Type 2 Blockers: A Novel Study ' by Alkuraishy H].WebmedCentral 2012;2(12):WMCRW001254
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