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Gorham Disease an Enigma
By Dr. Prashant Kothari
Submited on: 19 Jan 2012 01:49:34 PM GMT
Published on: 20 Jan 2012 12:00:40 PM GMT
 
Gorham Disease
Posted by Dr. William J Maloney on 07 Feb 2014 03:29:46 PM GMT Reviewed by Interested Peers

  • What are the main claims of the paper and how important are they?

    The author's aim is to describe a case report of Gorham disease.


  • Are these claims novel? If not, please specify papers that weaken the claims to the originality of this one.

    Yes


  • Are the claims properly placed in the context of the previous literature?

    Yes


  • Do the results support the claims? If not, what other evidence is required?

    Yes


  • If a protocol is provided, for example for a randomized controlled trial, are there any important deviations from it? If so, have the authors explained adequately why the deviations occurred?

    No


  • Is the methodology valid? Does the paper offer enough details of its methodology that its experiments or its analyses could be reproduced?

    Yes


  • Would any other experiments or additional information improve the paper? How much better would the paper be if this extra work was done, and how difficult would such work be to do, or to provide?

    No


  • Is this paper outstanding in its discipline? (For example, would you like to see this work presented in a seminar at your hospital or university? Do you feel these results need to be incorporated in your next general lecture on the subject?) If yes, what makes it outstanding? If not, why not?

    Yes- It would be a great seminar in a dental school


  • Other Comments:

    Gorham disease was first described in 1938 and reviewed extensively by Gorham in 1955.  It is also known as Vanishing Bone Disease, Massive Osteolysis, Gorham-Stout Syndrome, and Phantom Bone Disease.  Gorham disease is characterized by the destruction of bone which is replaced by vascular proliferation followed by dense fibrous tissue.

    The authors state that a differential diagnosis is eosinophillic granuloma and osteomyelitis.  Various radiographs are presented and analyzed.  Histopathological findings are also discussed.

  • Competing interests:
    None
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:

    No

  • Experience and credentials in the specific area of science:

    Clinical associate professor

  • How to cite:  Maloney W J.Gorham Disease[Review of the article 'Gorham Disease an Enigma ' by Kothari P].WebmedCentral 2012;5(2):WMCRW002953
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Gorhan disease
Posted by Dr. Constantino Ledesma-Montes on 13 Feb 2012 06:58:20 PM GMT

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? Yes
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? No
10 Are the references adequate and are they all necessary? No
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    It is an interesting and unisual case of Gorham disease. Presentation is almost good. In this special kind of cases it is necessary to make a good review of the literature. To do this will improve the quality and importance of the manuscript. Also, a high quality photomicrograph is necessary.

  • Competing interests:
    No
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    I am an 30 years expererience Oral and Maxillofacial Pathologist.

  • How to cite:  Ledesma-Montes C .Gorhan disease[Review of the article 'Gorham Disease an Enigma ' by Kothari P].WebmedCentral 2012;3(2):WMCRW001485
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review of gorham disease
Posted by Dr. Harshita Nahata on 03 Feb 2012 12:06:15 PM GMT

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    good article

  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    masters in orthopedics

  • How to cite:  Nahata H .review of gorham disease[Review of the article 'Gorham Disease an Enigma ' by Kothari P].WebmedCentral 2012;3(2):WMCRW001457
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