Open Access Biomedical Publisher Using Post Publication Peer Review
The author claims that use of n-acetylcarnosine eye drops improved the subjects cataract
The claims are not novel, as there have been many hundreds of such benefits. However, it is rare that a case study is presented formally in a learned publication
Yes. The finds reported by the author ar typical to those reported informally bothers
This is only one case report, with the obvious limitations
There is a need for a more full and complete clinical trial with many participants
As a single case report it is interesting to notice that the results confirm other published and unpublished literature. The improvement of sensitivity to glare is typical. There has been a lot of commercial interest in these drops and it is necessary to reportany further cases in a way that is separate from commerciall bias
Kyriazis M, The Cataract Cure, iUniverse publishing 2012
The conclusions drawn are scientifically sound and correct, as far as a case report concerns. The author acknowledges similar work done before and provides references to that.
I`d suggest to change the title as follows: Positive effects of Topical N-Acetylcarnosine (eye drops) on Cataract-Inhibited Vision in an Elderly subject - A Case Report...
The 1st phrase in the Introduction section needs revision.
As cardiologist I have no specific ophtalmology therapeutic area expertise.......it is the methodological part that I can judge on.
The topic is interesting. However nothing has been said on ethical cosniderations applied in this study. Moreover, the conclusion based on the study on one person is not so much strong.
I think if there was a few patients as control to the patient in the intervention, the conclusion would be stronger. Please add a few sentences on suggestions for future studies and limitations
Best wishes for the author
I am a nurse and in the nursing science the conclusion on new measures to replace known and previous treatments should be with caution.
1. Too many references for a case report.
2. Babizhayev references could be condensed.
3. Conclusion (A mechanism of action for this drug needs to be established through additional research in this
Research Assistant Professor.
This case report is of interest, and the manuscript is well written, documented and organized.
Too many references for a case report. Suggest to reduce to half.
I am a pulmonologist and therefore have no experience in this area.
Anesthesia, pain management
Although this is only a case and no firm conclusion can be reached from the results of any single case study, this report is very prospective and an interesting issue.
So, novel studies are needed as clinical investigation.
The work appears clear from the optmetrist point of view. But what are the other conditions of the eye which can only confirmed by an ophthalmologist. What is the improvement in each eye. The discussion deals heavly with the surgical treatment of cataract but in this report the focus is on medical management of cataract and also not alternative management. What about the complaince and correct methodology of applying the eye drops. And finally one small doubt -- who are "Doctors of Optometry" ? Are they optometricians.
Worked as Government medical officer where cataract surgery camps were conducted, supervised a optometrician in the government hospital.
The subject is partly outside the field of alternative medicine, the drug in object does not appear to be strictly considered as an alternative/non conventional treatment.
The paper is not original since the topic has been addressed in many studies before. It has value as a case report corroborating the evidence of a positive effect of the drug.
I suggest to include a brief description of the mechanism by which the drug would exert its effect: antioxidant, etc...
Too many references for a case report, most of them by the same author: should be cut by 50% at least.
Practitioner of alternative/complementary medicine.
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