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Article reported the evaluation of Analgesic and Antipyretic Potentials of indigenous plant Callicarpa macrophylla. This report is really worth for the phytochemist as they can now have reason to isolate the active phytoconstituents for the reported activity.
Yes, claims are novel.
In previous literature, no one have scientifically claim analgesic and antipyretic potential of C. macrophylla leaves.
No, it is not required here now.
Yes, it is scientifically valid.
No, but further research can be certainly encouraged.
Yes, to some extent.
It would like to encourage all the scientists to work more on the natural products as they are structurally more precise and significant for the specific active site of target receptor.
We have done some significant studies on natural products.
1.Use of natural plant remedies for common ailments like pain / fever
2.To test the efficacy of the extract of leaves
Establishment of plant extracts for common ailments forms the basic step in evaluation
Although use of plant products is encouraging, the pharmacological profile of the extracts need to be established before proceeding further.
Pharmacodynamics of the plant extracts along with the complete list of constituents need to be established to add strength to the study.
Extract analysis to document the constituents and pharmacodynamics would be useful
The study may need to go through further phases to establish the efficacy and safety in human subjects before making any comments
Drug potency and quantity evaluation comparing generic and hospital supply in a ICMR project
To prove the use of native botanical drug. It is very important for developing countries to find this type of medicine.
Yes. As far as the knowledge in this kind of subject is new, the work is welcome.
I think so.
No, the work was wll conducted
Of course we are waiting for the following paper, using anima nobili.
I think we should encourage more papers of this kind, especially in developing countries.
I am a medicine professor in a developing country
analgesic and antipyretic effect of plant extracts is claimed.
Already many analgesic and antipyretic preparations are avilable and so the need for testing this or advantages of this over some existing preparations has not been clearly stated.
For this to be made clear, statisticat tests of significance needs to be applied
Dose response relationship also needs to be established or clearly stated
Yes but the concentartion of the active principle in the herbal powder is not established
Above mentioned suggestions if incorporated would improve the paper
not outstanding but has potential to be good
familiar with epidemiological study designs and with Pharmacognosy
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