Open Access Biomedical Publisher Using Post Publication Peer Review
This is a review article on the important topic of developing cancer vaccines.
It seems that the majority of papers in the References list are review papers. The article would have been stronger, if the author had analyzed a larger number of original articles on cancer vaccines. It would be interesting to learn more details about cancer vaccines, their clinical efficacy, and what can be concluded from the available data.
Characiejus D, Jacobs JJ, Pašukonien? V, Kazlauskait? N, Danilevi?i?t? V, Mauricas M, Den Otter W. Prediction of response in cancer immunotherapy. Anticancer Res 31: 639-647, 2011
The paper gives short review the current trends in development of anti-cancer vaccines. Some promising types of vaccines that are in pre-clinical or clinical trials are presented.
Tables or diagrams that compare different types of vaccines could do the presented material much more presentable.
The paper is good constructed as a mini-review or lecture for students but it is not outstanding scientific review, becouse it does not include something new for discussion or new ideas, and the list of references is too small for rigorous review paper. I think, I'll use this information in my lectures for students.
I have some experience in experimental immunotherapy of cancer with vaccines.
The review on cancer vaccine is a very common topics of discussion. The author can provide a table showing different vaccine candidates. A graphical representation showing different vaccine and its downstream mechanism could have further added more informations to this subject.
Yes I have worked on development of vaccine in the form of recombinant protein, DNA vaccine and phage display antigens. I am also presently working on mechanism of protective immune response for more than 10 years.
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