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The authors hope to devise a diagnostic tool based on changes in cortisol levels to assist in early diagnosis of neurological disorders.
Yes, This would make an excellent presentation for a wide array of healthcare professionals.
100 volunteers were exposed to conditions to provoke a yawning response. A study protocol is presented to discover the extent to which cortisol may be implicated during yawning. A detailed section on the method and analysis is provided by the authors. A further longitudinal study is planned.
Clinical Associate Professor
The authors suggest that yawning raises cortisol levels akin to that seen in stress and fatigue. They also claim that the EMG data collection would be a novel feature of their proposed trial.
Exclusion criteria have not included Renal diorders, congestive heart states, certain respiratory disorders and history of stress states. Specification of timing of collection of salivary samples with justification is required.
This study may shed some light or contribute partially to evidence to link between yawning salivary cortisol, which itself needs time-testing. The authors themselves speculate that several subjects will not exhibit yawning response upon exposure to the guideline-stimuli.
Clarification is required for the relation especially causal-effect between salivary cortisol and yawning.
Clarification whether salivary cortisol levels are raised above normal even before yawning response; only then the importance of this trial for neurological disorders and justification of the title of the article.
This article proposes that there is a realtionship between one's cortisol level and yawning. This opens up the field of neurology, where yawning may in the future be seen as a symptom of a disease/disorder.
The claims ARE novel
As the article is proposing a new hypothesis, there is limited previous literature where comparision can be made.
The results support the claim that there is a link between cortisol levels and yawning. However further investigation is needed in determining its validity, i.e., rule of extraneous variables.
There are no deviations
The method is valid, enabling repeat of this investigation by other researchers.
Additional information that would help this article will predominately come from its reproduction with slight alternations from further investigations.
This article is outstanding in the fact that it is a new hypothesis that is currently being investigated. I would think/hope this article will be referred to as a foundation to future work within this field.
The objective is to investigate relationship between th cortisol levels and yawning. It is an interesting and novel scope to understand yawning.
The claims are novel.
Yes. The reference Nr 2 is not correct. It should be "WMC Neurology" and not "Neurology"
The methodology is valid
The information provided is sufficient.
No other comments
No experience in the field of yawning research
Cortisol and yawning are linked - this is such an important idea with a lot of implications.
Yes, they are novel. I have not read them before.
Protocol paper so results are not yet known.
This paper is well-written and is an exciting study protocol. Appropriately wrtten.
Yes, totally valid.
I do not think so.
Yes, it is. I am not aware that this work has been done before. I highly commend the authors.
I believe Author 1 has an interesting and novel hypothesis. I am looking forward to the data.
Purports to investigate a most interesting phenomenon about cortisol levels and yawning - highly relevant to neurology.
Yes, they are completely novel. I am unaware of them actually being investigated, to date.
It is a study protocol so I eagerly await findings.
Yes. It is the first, as far as I am aware.
Assist in neurological assessment.
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