Submited on: 27 Oct 2012 12:53:50 PM GMT
Published on: 29 Oct 2012 07:51:37 PM GMT

  • What are the main claims of the paper and how important are they?

    Claims are scientific and provide good information.

  • Are these claims novel? If not, please specify papers that weaken the claims to the originality of this one.


  • Are the claims properly placed in the context of the previous literature?


  • Do the results support the claims? If not, what other evidence is required?


  • If a protocol is provided, for example for a randomized controlled trial, are there any important deviations from it? If so, have the authors explained adequately why the deviations occurred?


  • Is the methodology valid? Does the paper offer enough details of its methodology that its experiments or its analyses could be reproduced?


  • Would any other experiments or additional information improve the paper? How much better would the paper be if this extra work was done, and how difficult would such work be to do, or to provide?

    Clinical trials should be done.

  • Is this paper outstanding in its discipline? (For example, would you like to see this work presented in a seminar at your hospital or university? Do you feel these results need to be incorporated in your next general lecture on the subject?) If yes, what makes it outstanding? If not, why not?

    This work should be presented in seminar / Conferences.

  • Other Comments:

    Very good review . The roles and mechanisms of prebiotic, probiotic and synbiotic in clinical applications are well  highlighted and presented and this will surely help to undertake future research studies.

  • Competing interests:
  • Invited by the author to review this article? :
  • Have you previously published on this or a similar topic?:
  • References:
  • Experience and credentials in the specific area of science:

    Very good

  • How to cite:  Choudhury, PhD, FICN, FACN (USA) J .Appraisal Of Probiotics And Prebiotics In Gastrointestinal Infections[Review of the article 'Appraisal of Probiotics and Prebiotics in Gastrointestinal Infections ' by Ghosh A].WebmedCentral 2012;3(11):WMCRW002319
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