Posted by Dr. William J Maloney on 14 Feb 2014 01:29:52 PM GMTReviewed by
Interested Peers
What are the main claims of the paper and how important are they?
The authors' aim is to compare the efficacy and safety of antifungal use for opportunistic infection in HIV patients.
Are these claims novel? If not, please specify papers that weaken the claims to the originality of this one.
Yes
Are the claims properly placed in the context of the previous literature?
Yes
Do the results support the claims? If not, what other evidence is required?
Yes
If a protocol is provided, for example for a randomized controlled trial, are there any important deviations from it? If so, have the authors explained adequately why the deviations occurred?
No
Is the methodology valid? Does the paper offer enough details of its methodology that its experiments or its analyses could be reproduced?
Yes
Would any other experiments or additional information improve the paper? How much better would the paper be if this extra work was done, and how difficult would such work be to do, or to provide?
No
Is this paper outstanding in its discipline? (For example, would you like to see this work presented in a seminar at your hospital or university? Do you feel these results need to be incorporated in your next general lecture on the subject?) If yes, what makes it outstanding? If not, why not?
Yes- this would be a great seminar for anyone involved in direct patient care.
Other Comments:
The most common fungal infections in individuals with HIV are candidiasis, cryptococcal meningitis and histoplasmosis. The authors state that therapeutic regimens which are recommended induce various types of adverse reactions or side effects. They suggest routine drug adjustment and therapeutic drug monitoring. This article is extremely well referenced.
Invited by the author to review this article? : No
Have you previously published on this or a similar topic?: No
References:
None
Experience and credentials in the specific area of science:
Clinical associate professor
How to cite: Maloney W J.Antifungal Use for Opportunistic Infection in HIV Patients[Review of the article 'Antifungal Use for Opportunistic Infection in HIV Patients: Comparison of Efficacy and Safety ' by Harun S].WebmedCentral 2014;5(2):WMCRW002981
The authors' aim is to compare the efficacy and safety of antifungal use for opportunistic infection in HIV patients.
Yes
Yes
Yes
No
Yes
No
Yes- this would be a great seminar for anyone involved in direct patient care.
The most common fungal infections in individuals with HIV are candidiasis, cryptococcal meningitis and histoplasmosis. The authors state that therapeutic regimens which are recommended induce various types of adverse reactions or side effects. They suggest routine drug adjustment and therapeutic drug monitoring. This article is extremely well referenced.
No
No
None
Clinical associate professor