Submited on: 09 Jan 2014 05:40:02 AM GMT
Published on: 09 Jan 2014 06:34:38 AM GMT
 
Cough-Induced Transient Global Amnesia
Posted by Dr. William J Maloney on 14 Feb 2014 02:40:30 PM GMT Reviewed by Interested Peers

  • What are the main claims of the paper and how important are they?

    The purpose of this paper is to describe two case of patients who developed acute loss of short term memory loss of several hours duration following a crisis of severe coughing.


  • Are these claims novel? If not, please specify papers that weaken the claims to the originality of this one.

    Yes


  • Are the claims properly placed in the context of the previous literature?

    Yes


  • Do the results support the claims? If not, what other evidence is required?

    Yes


  • If a protocol is provided, for example for a randomized controlled trial, are there any important deviations from it? If so, have the authors explained adequately why the deviations occurred?

    No


  • Is the methodology valid? Does the paper offer enough details of its methodology that its experiments or its analyses could be reproduced?

    Yes


  • Would any other experiments or additional information improve the paper? How much better would the paper be if this extra work was done, and how difficult would such work be to do, or to provide?

    No


  • Is this paper outstanding in its discipline? (For example, would you like to see this work presented in a seminar at your hospital or university? Do you feel these results need to be incorporated in your next general lecture on the subject?) If yes, what makes it outstanding? If not, why not?

    Yes- it would be a great seminar for a group of neurologists.


  • Other Comments:

    Transient global amnesia is a condition defined by the abrupt loss of short term memory while preserving autobiographic memory and in the absence of localizing signs on the neurological examination.  The author suggests that selective transient ischemia of the hippocampus during a coughing crisis may precipitate transient global amnesia.  This is a form of cough-induced persistent cognitive migraine aura without stroke.

  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    Clinical associate professor

  • How to cite:  Maloney W J.Cough-Induced Transient Global Amnesia[Review of the article 'Cough-Induced Transient Global Amnesia ' by Jacome D].WebmedCentral 2014;5(2):WMCRW002984
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Cough-induced transient global amnesia by Daniel E. Jacome
Posted by Prof. Uner Tan on 20 Jan 2014 08:34:30 PM GMT Reviewed by WMC Editors

  • What are the main claims of the paper and how important are they?

    The author presented two patients developed acute loss of short term memory of several hours duration while preserving autobiographic memory and exhibiting no focal signs and symptoms following a crisis of severe coughing.

    It was suggested that selective transient ischemia of the hippocampus during coughing crisis may precipitate TGA in exceptional patients, as a form of cough-induced persistent cognitive migraine aura without stroke. The results are extremely interesting and worh for publishing.


  • Are these claims novel? If not, please specify papers that weaken the claims to the originality of this one.

    Yes


  • Are the claims properly placed in the context of the previous literature?

    Yes


  • Do the results support the claims? If not, what other evidence is required?

    Yes


  • If a protocol is provided, for example for a randomized controlled trial, are there any important deviations from it? If so, have the authors explained adequately why the deviations occurred?

    There is no controlled trial.


  • Is the methodology valid? Does the paper offer enough details of its methodology that its experiments or its analyses could be reproduced?

    Yes


  • Would any other experiments or additional information improve the paper? How much better would the paper be if this extra work was done, and how difficult would such work be to do, or to provide?

    No


  • Is this paper outstanding in its discipline? (For example, would you like to see this work presented in a seminar at your hospital or university? Do you feel these results need to be incorporated in your next general lecture on the subject?) If yes, what makes it outstanding? If not, why not?

    Yes


  • Other Comments:

    No

  • Competing interests:
    None
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:

    None

  • Experience and credentials in the specific area of science:

    I have suitable experience and knowledge to review this paper.

  • How to cite:  Tan U .Cough-induced transient global amnesia by Daniel E. Jacome[Review of the article 'Cough-Induced Transient Global Amnesia ' by Jacome D].WebmedCentral 2014;5(1):WMCRW002918
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