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Clinical Complexities Of Parkinson's Disease: An Updated View - REVIEW

Posted by Mr. Santiago Perez Lloret on 31 Jan 2011 02:09:33 PM GMT

1	Is the subject of the article within the scope of the subject category?	Yes
2	Are the interpretations / conclusions sound and justified by the data?	No
3	Is this a new and original contribution?	No
4	Does this paper exemplify an awareness of other research on the topic?	No
5	Are structure and length satisfactory?	Yes
6	Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience?	Yes
7	Can you suggest any reductions in the paper, or deletions of parts?	No
8	Is the quality of the diction satisfactory?	Yes
9	Are the illustrations and tables necessary and acceptable?	No
10	Are the references adequate and are they all necessary?	Yes
11	Are the keywords and abstract or summary informative?	Yes

Other Comments:
The authors did a good work in trying to sum up some of the most disturbing problems in parkinson's disease (PD). Nonetheless, I have some major remarks,

1. Authors speak about the non-dopaminergic origin of many of these sympotms without giving evidence about it. This is important, specially in view of possible treatments.

2. Some very important adverse reactions to dopaminergic therapy, i.e. impulse-control disorders, represents also clinical complexities in PD but were not included in the review.

3. Similarly important symptoms such apathy, fall, fear to fall, etc were negleted or insuficiently described.

4. I would have loved to see a table summing up the reviewed complexities.

5. Some references are missing, for example in the "Voice Changing / sialorrhea" section.
Competing interests:
No
Invited by the author to review this article? :
No
Have you previously published on this or a similar topic?:
Yes
References:
Decision-making in Parkinson's disease patients with and without pathological gambling. Rossi M, Gerschcovich ER, de Achaval D, Perez-Lloret S, Cerquetti D, Cammarota A, In?s Nouzeilles M, Fahrer R, Merello M, Leiguarda R. Eur J Neurol. 2010 Jan;17(1):97-102. Epub 2009 Sep 23. Parkinson's disease sleep scale, sleep logs, and actigraphy in the evaluation of sleep in parkinsonian patients. Perez-Lloret S, Rossi M, Nouzeilles MI, Trenkwalder C, Cardinali DP, Merello M. J Neurol. 2009 Sep;256(9):1480-4. Epub 2009 Apr 29. Validation of a new scale for the evaluation of sialorrhea in patients with Parkinson's disease. Perez Lloret S, Pir?n Arce G, Rossi M, Caivano Nemet ML, Salsamendi P, Merello M. Mov Disord. 2007 Jan;22(1):107-11.
Experience and credentials in the specific area of science:

7 years in pharmacoepidemiological research in the area
How to cite: Perez Lloret S .Clinical Complexities Of Parkinson's Disease: An Updated View - REVIEW[Review of the article 'Clinical Complexities Of Parkinson's Disease: An Updated View ' by Goyal A].WebmedCentral 2011;2(1):WMCRW00429

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Clinical Complexities Of Parkinson's Disease: An Updated View

Posted by Prof. Pawan Krishan on 22 Jan 2011 03:36:15 PM GMT

1	Is the subject of the article within the scope of the subject category?	Yes
2	Are the interpretations / conclusions sound and justified by the data?	Yes
3	Is this a new and original contribution?	No
4	Does this paper exemplify an awareness of other research on the topic?	Yes
5	Are structure and length satisfactory?	Yes
6	Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience?	No
7	Can you suggest any reductions in the paper, or deletions of parts?	No
8	Is the quality of the diction satisfactory?	Yes
9	Are the illustrations and tables necessary and acceptable?	Yes
10	Are the references adequate and are they all necessary?	Yes
11	Are the keywords and abstract or summary informative?	Yes

Other Comments:
The article may be accepted for publication.
Competing interests:
no
Invited by the author to review this article? :
No
Have you previously published on this or a similar topic?:
No
References:
None
Experience and credentials in the specific area of science:

14 years
How to cite: Krishan P .Clinical Complexities Of Parkinson's Disease: An Updated View [Review of the article 'Clinical Complexities Of Parkinson's Disease: An Updated View ' by Goyal A].WebmedCentral 2011;2(1):WMCRW00401

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