Submited on: 12 Dec 2010 06:59:04 PM GMT
Published on: 13 Dec 2010 03:01:05 PM GMT
 
Scientific
Posted by Dr. Devaraj MG on 18 Mar 2011 08:03:47 AM GMT

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? Yes
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    The author could include more literature data on the chemical profiling of Orthosiphon stamineus leaves. This is the palnt which is extensively searched for the phytochemicals because of the plant's extraordinary pharmacological properties.

  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    Clinical biochemical studies in cancer

  • How to cite:  MG D .Scientific[Review of the article 'Medicinal Potentials Of Orthosiphon Stamineus Benth ' by Abdul Majid A].WebmedCentral 2011;2(3):WMCRW00596
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? No
3 Is this a new and original contribution? No
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? Yes
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? No
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    Recently there is a wave among the researchers which tries to investigate and confirm the medical effects of herbal drugs. They emphasizes on the scientific approach to the traditional part of medicine. The current manuscript is talking about the Orthosiphon Stamineus and its medical features.

     

    The English writing of the manuscript is good.

    There are few typographical errors within the manuscript. References were not provided for the paragraph describing about the anti-inflammatory effect of O. stamineus.

     

    Regarding the O. stamineus’s anti-microbial activity, it would be better that authors mention if the extract was experimented in other microbial species, but demonstrated no anti-microbial effect.

    “After repeated daily oral administrations of the extract for 14 days, the extract significantly reduced plasma glucose concentration in diabetic rats at days 7 and 14. By the end of the study, plasma triglyceride concentration was lower in the extract-treated diabetic rats than untreated ones. Furthermore, plasma HDL-cholesterol concentration was significantly increased in diabetic rats treated with the extract.” This statement was repeated twice in the hypoglycemic agent part.

    Referencing had some problems. There are some numbers at the end of some sentences, which seems to be related to a reference, but did not. It seems that changing the bibliographic format from Vancouver style to the Harvard style may led to this problem.

    It’s better to add a paragraph for conclusion at the end of the manuscript, to make it possible for the readers who just want to take a look at the article, achieve the main concept of the manuscript.

     

  • Competing interests:
    There was no conflicting interest.
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    Yes
  • References:
    None
  • Experience and credentials in the specific area of science:

    I had some experiences in this field since 5 years ago

  • How to cite:  Sepehrvand N .Orthosiphon stamineus: a potentially useful herbal drug[Review of the article 'Medicinal Potentials Of Orthosiphon Stamineus Benth ' by Abdul Majid A].WebmedCentral 2011;2(1):WMCRW00420
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1 Is the subject of the article within the scope of the subject category? Partly
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? Yes
7 Can you suggest any reductions in the paper, or deletions of parts? Yes
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    The article is well descriptive in describing the general medical significance of Orthosiphon Stamineus Benth. As the subject category is concerned, it should be more elaborative in Synergic enhancer to tamoxifen and other antitumor related applications.

  • Competing interests:
    No
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    Yes
  • References:
    F. L. Ansari, et al. Combinatorial Synthesis and Antitumour Studies on an Aryl and Heteroaryl Chalcone Library using Positional Scanning Method, Chem. & Biodiv. 2007, 4, 203-214.
  • Experience and credentials in the specific area of science:

    I have worked on the designing and synthesis of small molecular libraries of medicinally important cytotoxic/antitumor compounds.

  • How to cite:  Nazir S .S. Nazir. The review of Medicinal Potentials Of Orthosiphon Stamineus Benth.[Review of the article 'Medicinal Potentials Of Orthosiphon Stamineus Benth ' by Abdul Majid A].WebmedCentral 2011;2(1):WMCRW00347
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? Yes
7 Can you suggest any reductions in the paper, or deletions of parts? Yes
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    The paper defined its contents as a cancer research, so it would be better to extent the content about the “O. stamineus as Synergistic enhancer to tamoxifen and other related research. At the same time to remove some contents such as "O. stamineus as a hypoglycemic agent".

      

  • Competing interests:
    No
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    Yes
  • References:
    Yan Y. Regulation of Vid-dependent degradation of FBPase by TCO89, a component of TOR Complex 1. Int. J. Biol. Sci. 2010, 6:pp361-370. ♦Yan Y. et al. The regulatory mechanism of Warts and the role of Hippo pathway in adult stem cell proliferation in Drosophilae. Darrence Publish Co. USA. 2010. ♦Yan Y. et al. Tor Complex II regulating actin organization in Saccharomyces cerevisiae. Darrence Publish Co. USA. 2010
  • Experience and credentials in the specific area of science:

    I have worked on an oncogene and a tumor suppressor pathway in cancer research.

  • How to cite:  Yan Y .The review of Medicinal Potentials Of Orthosiphon Stamineus Benth.[Review of the article 'Medicinal Potentials Of Orthosiphon Stamineus Benth ' by Abdul Majid A].WebmedCentral 2011;1(12):WMCRW00308
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