Submited on: 04 Mar 2011 10:53:28 AM GMT
Published on: 04 Mar 2011 02:06:32 PM GMT
 

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? No
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? Yes
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? No
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    Although the title of the paper refers to the aetiology of Alzheimer's disease, the topic is not developed in the work.

    I would suggest to consider the hypothesis proposed, separately and simultaneously, by Flanary (Flanary B., 2009. Telomeres: Function, Shortening, and Lengthening [Expert Commentary], in Telomeres: Function, Shortening and Lengthening, Nova Science Publishers Inc., New York) and Libertini (Libertini G., 2009. The Role of Telomere-Telomerase System in Age-Related Fitness Decline, a Tameable Process, in the same book), following the work of Fossel (Fossel MB, 1996. Reversing Human Aging. New York, William Morrow and Company; Fossel MB, 2004. Cells, Aging and Human Disease. New York, Oxford University Press), about the genesis of the disease in the decline of microglial cell turnover.

    The determination of Alzheimer’s disease exact aetiology is crucial because the ignorance of it determines the focus on the accumulation of certain substances and the subsequent neurological and physiological impairments that are only consequences.

  • Competing interests:
    No
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    Yes
  • References:
    Please, see the comment and Libertini G. (2009) Prospects of a Longer Life Span beyond the Beneficial Effects of a Healthy Lifestyle, in Handbook on Longevity: Genetics, Diet & Disease, Nova Science Publishers Inc., New York.
  • Experience and credentials in the specific area of science:

    Please, see the comment and below

  • How to cite:  Libertini G .Alzheimer's disease: the aetiology is crucial[Review of the article 'Alzheimers Disease: Comprehensive Review of Aetiology, Diagnosis, Assessment Recommendations and Treatment. ' by Thompson S].WebmedCentral 2011;2(12):WMCRW001280
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    A deeply informative and thoroughly enjoyable read

  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    Clinical Researcher

  • How to cite:  Chinnery H .Alzheimers Disease: Comprehensive Review of Aetiology, Diagnosis, Assessment Recommendations and Treatment.[Review of the article 'Alzheimers Disease: Comprehensive Review of Aetiology, Diagnosis, Assessment Recommendations and Treatment. ' by Thompson S].WebmedCentral 2011;2(5):WMCRW00765
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    Topical; a worthwhile paper.

  • Competing interests:
    No
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    Assisting in rehabilitation

  • How to cite:  Thompson B ."Alzheimers Disease:Comprehensive"...................[Review of the article 'Alzheimers Disease: Comprehensive Review of Aetiology, Diagnosis, Assessment Recommendations and Treatment. ' by Thompson S].WebmedCentral 2011;2(5):WMCRW00736
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    There has long been overdue such a comprehensive review of the subject as it is constantly changing. I congratulate the author!

     

  • Competing interests:
    none
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    Assisting in rehabilitation.

  • How to cite:  Jones N .Alzheimers Disease: Comprehensive Review of Aetiolgy, Diagnosis, Assessment Recommendations and Treatment.[Review of the article 'Alzheimers Disease: Comprehensive Review of Aetiology, Diagnosis, Assessment Recommendations and Treatment. ' by Thompson S].WebmedCentral 2011;2(3):WMCRW00566
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