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The present study was designed to evaluatethe Acid-phosphatase activity before and during orthodontic tooth movement in Albino rats to correlate histochemical changes with histological changes. This study whows that histochemical changes precede the histological changes during orthodontic tooth movement.
Author have been done good work however experiment on animal have legal concern about animal experimentation. It is very difficult in term study of tooth movement changes in human, so this study is very valuable.
References are not cited properly.
The present article evaluates the Acid-phosphatase activity before and during orthodontic tooth movement in Albino rats to correlate histochemical changes with histological changes. The results of the study revealed histochemical changes appear as early as 24 hours with intensely positive reaction to acid-phosphatase. Overall analysis reveal that histochemical changes precedes the histological changes.
This particular study in animal model will be of interest to the readership of your journal and an eye opener for further studies about similar subjects in animal or human models.
Vast clinical and accademic experience in the field of Orthodontics and Dentofacial Orthopaedics. Presently working as Professor in the same area in an accademic institution and also into clinical practice.
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