Submited on: 07 Jul 2011 06:04:47 PM GMT
Published on: 08 Jul 2011 05:38:10 PM GMT
 
A Comparison of Dexamethasone and Metoclopramide in orthognatic Surgery
Posted by Dr. William J Maloney on 14 Feb 2014 01:48:56 PM GMT Reviewed by Interested Peers

  • What are the main claims of the paper and how important are they?

    The author's main purpose of this article is to compare the efficiency of dexamethasone and metaclopramide in the prevention of postoperative nausea and vomiting.


  • Are these claims novel? If not, please specify papers that weaken the claims to the originality of this one.

    Yes


  • Are the claims properly placed in the context of the previous literature?

    Yes


  • Do the results support the claims? If not, what other evidence is required?

    Yes


  • If a protocol is provided, for example for a randomized controlled trial, are there any important deviations from it? If so, have the authors explained adequately why the deviations occurred?

    No


  • Is the methodology valid? Does the paper offer enough details of its methodology that its experiments or its analyses could be reproduced?

    Yes


  • Would any other experiments or additional information improve the paper? How much better would the paper be if this extra work was done, and how difficult would such work be to do, or to provide?

    No


  • Is this paper outstanding in its discipline? (For example, would you like to see this work presented in a seminar at your hospital or university? Do you feel these results need to be incorporated in your next general lecture on the subject?) If yes, what makes it outstanding? If not, why not?

    Yes- this would be a great seminar for oral surgery residents.


  • Other Comments:

    Postoperative nausea and vomiting is one of the most frequent side effects of general anesthesia.  The author states that the use of preoperative dexamethasone significantly reduced the incidence of postoperative nausea and vomiting as compared with metoclopramide.  The author recommends the prophylactic administration of 8mg of IV dexamethasone one minute prior to the induction of anesthesis.

  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    Clinical associate professor

  • How to cite:  Maloney W J.A Comparison of Dexamethasone and Metoclopramide in orthognatic Surgery[Review of the article 'Dexamethasone Compared with Metoclopramide in Prevention of Postoperative Nausea and Vomiting in Orthognathic Surgery ' by Gashi A].WebmedCentral 2011;5(2):WMCRW002982
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    A very nice paper with a clear approach to comparing antiemetic methods in specific surgery.  I appreciate the opportunity to review this paper.

  • Competing interests:
    no
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    Pediatric anesthesia, postoperative pain, etc.

  • How to cite:  Hasani A . Dexamethasone Compared with Metoclopramide in Prevention of Postoperative nausea and Vomiting in Orthognathic Surgery[Review of the article 'Dexamethasone Compared with Metoclopramide in Prevention of Postoperative Nausea and Vomiting in Orthognathic Surgery ' by Gashi A].WebmedCentral 2011;2(7):WMCRW00863
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    Interesting paper comparing dexamethasone and metoclopramide for prevention of PONV in orthognathic surgery.

    The study is well designed and conducted. According to the results of the study dexamethasone seems to offer some advantage over metoclopramide.

  • Competing interests:
    none
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    Yes
  • References:
    Luchetti M, Palomba R, Liardo A, De Robertis E, Scioli G. Use of ondansetron in the prevention of post-operative nausea and vomiting (PONV) after videolaparoscopic cholecystectomy (VLC). Minerva Anestesiologica 1993; 59,10,suppl.2:182.
  • Experience and credentials in the specific area of science:

    Twenty years of anaesthesia practice.

  • How to cite:  Luchetti M .Dexamethasone vs Metoclopramide for prevention of postoperative nausea and vomiting[Review of the article 'Dexamethasone Compared with Metoclopramide in Prevention of Postoperative Nausea and Vomiting in Orthognathic Surgery ' by Gashi A].WebmedCentral 2011;2(7):WMCRW00845
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