Submited on: 20 Sep 2011 12:42:11 PM GMT
Published on: 20 Sep 2011 02:13:52 PM GMT
 

1 Is the subject of the article within the scope of the subject category? Partly
2 Are the interpretations / conclusions sound and justified by the data? Partly
3 Is this a new and original contribution? No
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? No
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? Yes
8 Is the quality of the diction satisfactory? No
9 Are the illustrations and tables necessary and acceptable? No
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    This MS does not qualify the merits of a full length paper. It would have been better if it would have been stated as a short communication. The abstract first few lines are a part of introduction. The ain of any abstract should be to mention the objective methodology results and conclusion which is not reflected in this MS. No pertinent reference is mentioned in the introduction or materials and methods. The results are described as observations which is not proper. The spelling of Observations is not correct. There are a plenty of question marks typed in the text of observations and discussion which make no meaning and rather confuse the understandingThe Units for TSH levels are not mentioned and Tables 1, 2 and 3 seem to be unneccessary and can be replicated in the text. No mention of procedures used for the daignosis of proliferative endometrium and endometrial hyperplasia or ovulation studies in materials and methods. The manner of reference citation in the text is inappropriate and the reference list mentions references most of which are too old. Overall the organization of the entire manuscript is messy and does not clearly reflect the work. 

  • Competing interests:
    No
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    work experience in reproduction

  • How to cite:  Purohit G N.Thyroid Dysfunction in Dysfunctional Uterine Bleeding[Review of the article 'Thyroid Dysfunction in Dysfunctional Uterine Bleeding ' by Sharma S].WebmedCentral 2011;2(9):WMCRW00960
1 2 3 4 5 6 7 8 9
Report abuse
 

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? No
3 Is this a new and original contribution? No
4 Does this paper exemplify an awareness of other research on the topic? No
5 Are structure and length satisfactory? No
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? No
9 Are the illustrations and tables necessary and acceptable? No
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? No
  • Other Comments:

    Title: Needs to be revised to: Thyroid function in women undergoing investigation for abnormal uterine bleeding. Abstract: If diagnosis of dysfunctional uterine bleeding(DUB) depends on the exclusion of general and local disease condition, how was the diagnosis made in the 100 women? Not just TSH,but also T4 and T3 need to be assessed, among other investigations before a diagnosis of DUB could be made. Introduction: Line 1 should read-Thyroid hormone dysfunction may present clinically as altered menstrual pattern in women of reproductive age. Materials and methods 100 premenopausal women were used. Did this mean climacteric women or women in reproductive age? How were the 100 women selected? From previous reports, if any, what is the local prevalence of thyroid dysfunction and DUB and how was a sample size calculated if was done? Ethically, is TSH assay a routine investigation at your facility for women with abnormal uterine bleeding? If not, did the women know they were partaking in research, was consent got and who paid for the laboratory investigation? Results NONE. Rather Observation was used and from table 1, 85 women were euthyroid while 15 women had abnormal TSH. This implies that this article was written on 15 women with abnormal TSH levels and menstrual pattern. Also, only serum TSH level was assessed. T4 and T3 levels were not estimated and the justification for this was not stated and discussed in the discussion part of the article. Discussion Line 1 should read: Menstrual irregularities are common in women with thyroid disorders than in the general population. - there were so many ?(question marks) which presented the authors as not meticulous enough. - Discussion did not discuss the findings of the authors but just compared findings with previously published articles. - The conclusion of the authors is nothing new as it is impossible to reliably make a diagnosis of DUB without doing hormone assay including T4and T3 and not just TSH estimation. - How the authors confirmed that 85.7% of hypothyroid women had anovulatory cycles was not stated. Was day 21 serum progesterone, endometrial curretage or pelvic ultrasound scan done to know this? If so, another table is required to show ovulation status of the women. Conclusion Needs to re-written.

  • Competing interests:
    None
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    Good experience

  • How to cite:  Okusanya B O.Thyroid dysfunction in Dysfunctional Uterine Bleeding[Review of the article 'Thyroid Dysfunction in Dysfunctional Uterine Bleeding ' by Sharma S].WebmedCentral 2011;2(9):WMCRW00959
1 2 3 4 5 6 7 8 9
Report abuse