Case Report
 

By Dr. Bill Misner
Corresponding Author Dr. Bill Misner
American Holistic College of Nutrition , 1140 West Glass Avenue Spokane, Washington - United States of America 99205
Submitting Author Dr. Bill Misner
ALTERNATIVE MEDICINE

Coenzyme Q, Health, Energy, Exercise, Endurance Performance

Misner B. Coenzyme Q Effects the Endurance of the Runner Performance: A Case Report. WebmedCentral ALTERNATIVE MEDICINE 2011;2(12):WMC002548
doi: 10.9754/journal.wmc.2011.002548
No
Click here
Click here
Submitted on: 02 Dec 2011 06:28:00 PM GMT
Published on: 03 Dec 2011 08:06:07 PM GMT

Abstract


Manufacturers of Coenzyme Q10 present different reports in marketing Ubiquinol or Ubiquinone. Each one suggests that their product is more favorable for resolving compromised health issues or poor energy metabolism associated with aging. This case study reports the running performance of a 71-year male runner while taking Ubiquinol, or Ubiquinone, each for 90-days, or taking neither supplement following a 14-day washout period. The subject's best performance time on the same course while taking Ubiquinone was 2.28% faster than his time on the same course after a 14-day washout period without supplement dose. The subject's best performance time on the same course while taking Ubiquinol was –1.16% slower than his time on the same course after a 14-day washout period without supplement dose. The results from a single male subject are definitively inconclusive, but call for more research by collecting dose-aided and dose-fasted timed performances from a larger contingent of male and female runners of all ages.

Introduction


Coenzyme Q-10 (Ubiquinol or Ubiquinone) may enhance health quality and improve energy production with benefits for endurance and exercise performance. Supplement forms of CoQ10 are manufactured as Ubiquinol and Ubiquinone. Manufacturers present differing views to consumers for taking Ubiquinol or Ubiquinone:

UBIQUINOL
1.Ubiquinol is more absorbable (delivered by oil suspension) than conventional Ubiquinone in every clinical trial to date.
2.Ubiquinol conversion decreases with age or compromised health.
3.Ubiquinol is the predominant form (over 90%) of CoQ10 in healthy humans.

UBIQUINONE
1.Ubiquinone is absorbed at same rate as ubiquinol (over-double powdered ubiquinone in capsules).
2.Ubiquinone is stable exposed to air with no oxidation.
3.Ubiquinone is dispersible in water, beverages, or gels.

Ubiquinone is the oxidized form of Coenzyme Q10, while Ubiquinol is the reduced form of CoQ10. Following the absorption of the oral dose, Ubiquinone is enzyme-converted back to Ubiquinol, and, Ubiquinol is enzyme-converted back to Ubiquinone, recycled according to the body’s cellular energy demand or to the reduction of oxidative cell damages. Ubiquinone and/or Ubiquinol play an important role in regenerating two internal antioxidants, vitamin E and vitamin C. Within the electron transport chain, the antioxidant ratio of Ubiquinol:Ubiquinone produces ATP for energy metabolism (exercise) upon demand. Some scientists argue that Ubiquinol is best absorbed, while others argue that their proprietary form of Ubiquinone is absorbed as well as Ubiquinol. Since both forms of exogenous Coenzyme Q10 are proposed to raise serum levels higher than the other, the question that case study examined is which form produces the most energy (if any) for endurance and performance? Coenzyme Q-10 is made inside the human body in the form of two alternating endogenous substances, (Ubiquinone ? Ubiquinol); the amounts available may effect energy production and/or health status. Acute deficiency of Coenzyme Q-10 has been associated with fatigue and exercise intolerance, while chronic deficiency has been associated with more serious health issues such as cerebellar ataxia, obesity, cardiovascular heart disease, hypertension, Muscular Dystrophy, HIV, AIDS, Parkinson's, and Periodontal Disease (Dhanasekaran & Ren 2005, Gaby 1999). With aging, the body makes by the mitochondria cells less Coenzyme Q10 that significantly lowers energy metabolism and compromising health (Lenaz, G., et al.1998). Mitochondria, located inside all living cells, produces Coenzyme Q-10 (Ubiquinone and Ubiquinol) for energy production and healthy cell function. Half of the body’s total Coenzyme Q10 originates in mitochondrion where it performs three vital functions (Barbiroli, B., et al 1997; Papucci, L., et al.  2003):  

1.Assists enzymes in the mitochondria to convert dietary nutrients into adenosine triphosphate
2.Exerts antioxidant effects against free radicals generated during the energy-producing process
3.Protects the structural integrity of the mitochondrial membrane

Problem what prevents deficiency?
Meats from livestock-fish-poultry [3.0-3.5-ounces] that contain the most Coenzyme Q10 are also higher in fat. When consumed in amounts high enough to increase Coenzyme Q10, unwanted unhealthy blood lipids may increase more than what is regarded healthy:

Not-Healthy (high-fat) Foods CoQ-10 content [3.0-3.5-ounces]:
- Beef 2.60mg
- Herring 2.30mg
- Chicken 1.40mg

Healthy (low-fat) Foods CoQ-10 content is small [3.0-3.5-ounces]:
- Spinach 1.00mg
- Broccoli 0.86mg
- Rice Bran 0.54mg
- Sweet Potato 0.36mg
- Wheat Germ 0.35mg
- Soybeans 0.29mg
- Garlic  0.27mg
- Carrot  0.22mg
- Eggplant 0.21mg

Methods


Running performance slows down with age in years, months, and days. Loss of performance deteriorates approximately 0.6-1.0% per year. Because this case study required 180-days taking supplements and 14-days without taking supplements, the World Masters Athletics (WMA) WAVA-Age-grading calculator was selected to fairly compare all 21-timed runs of a 71-year age male subject on a same 15K trail course. The timed performances were age-graded by percentage of the world record 15K road race by age (in years, months, and days). All timed runs were recorded on the 2010 USA National 15K Championship trail course over a period of 194-days. This subject trained 5-days per week for 90-days to attain a base level of fitness. After this first 90-day period was completed, the subject commenced oral dose of 400 mg Ubiquinol daily for 90-days. During the second 90-day period, of twelve-timed trail runs recorded, the best time was 1:28:03. Immediately following completion of the second 90-day period, this subject commenced oral dose of 400 mg Ubiquinone daily for the third 90-day period. Of eight timed 15K trail runs recorded; the best was 1:23:53. After this third 90-day period, the subject fasted both Ubiquinol and Ubiquinone for 14-day washout period prior to recording his final 15K timed trail run in 1:26:58. Age-grading this subject’s timed performances precisely identified which timed run during each of two 90-day periods and one 14-day washout no-supplement period was faster or slower based on percentage of the world record 15K road race by exact age (in years, months, and days).

Results


Twenty-one (21) timed 15K trail runs recorded in 194-days. The best-timed runs during each dose or no dose period occurred at age 71.20 during the Ubiquinol-dose period, at age 71.47 during the Ubiquinone-dose period, and at age 71.62 immediately following a 14-day no-supplement washout period. The best-timed run was determined according to the percentage of the age-graded world record 15K road race for precise runner-age in years and days as listed in Table I.

Discussion


The average Coenzyme Q10 turnover every 4-days in a healthy person is 500 milligrams depending upon endogenous cellular production or exogenous dietary dose (Ernster 1995).  A healthy young person (age 20) stores a range estimate of 1400-2000 milligrams inside the cells. Specific foods either supply Coenzyme Q10 or the substances that the cells convert inside for cell stores. In the absence of exogenous sources (Example: 7-day fast), Coenzyme Q10 levels may decrease by -50%. Exercise also decreases circulating Q-l0 plasma levels observed in runners immediately following exercise (Bargossi, A. M., et al. 1993). Supplemental Coenzyme Q-l0 dose increases plasma levels, reduces muscle cell oxidant damages, and increases energy metabolism rebound for future exercise-demand (Gökbel et al., 2010; Bonetti A, et al., 2000; Cooke M, et al., 2008).  Individual needs vary remarkably, from as little as 30 milligrams to as much as 500 milligrams/day, depending upon endogenous synthesis rate and exogenous dietary or supplement donors. Researchers reported endurance of athletes supplementing CoQ10 who have higher muscle concentrations, and lower serum oxidative stress after exercise, resulting in increased exercise time to exhaustion (Cooke M, et al., 2008). When CoQ10 saturates tissues, health and energy metabolism appear to be optimal. Coenzyme Q-10 supplements prevent and resolve deficiencies immediately increase circulating plasma levels without elevating blood lipids (Quinzii et al., 2006). Exogenous Coenzyme Q-10’s half-life ranges between 33-72 hours, with blood serum concentrations peaking between 5-10 hours (6-hours average). Normal serum concentrations are 0.7-1.0 µg/mL. The therapeutic oral dose for maintaining healthy concentrations is 50-150 mg of Coenzyme Q10 per day (2 mg CoQ10 per kg of bodyweight/day). However, when a deficiency occurs, a higher oral dose is required to resolve. Aged individuals (over 70) have low Coenzyme Q-10 stores. Because since aging and exercise create a deficiency state, a daily oral dose of 400 mg CoQ10 daily has been proposed to improve cardiovascular senescent tolerance to aerobic exercise stress (Rosenfeldt et al., 1999). Peak performances recorded from this runner were 90-day training periods to attain peak performance at 15K trail run distance. This case reports a single subject 15K trail-run timed performances based on age-grading standards for 71.20-71.62-years was 2.28% faster while consuming 400 mg/day Ubiquinone than the same daily dose of Ubiquinol. This report begs the question whether a similar Ubiquinone loading protocol would benefit larger populations of other male and female runners of all ages. It must be emphasized that what occurred with this single male runner is a single case report, not a conclusive finding applicable to all populations.

Conclusions


This case report collected 21-timed 15K trail running performances from a fit 71-y male runner over an extended 194-day period, 180-days taking supplemental Ubiquinol or Ubiquinone, and a 14-day washout period taking no supplements. This subject ran +2.28% faster while taking Ubiquinone, than taking no supplements [post-14-day washout]. However, while taking Ubiquinol, this subject ran -1.16% slower than without taking no supplements. To determine whether or not performance is associated with exogenous Ubiquinone or Ubiquinol, more research is required by examining exogenous Ubiquinone and Ubiquinol-dose effects in larger contingents of male and female runners of all age ranges.

Acknowledgements


The author expresses appreciation to (1) Best Formulations, 938 Radecki Ct, City of Industry, CA 91748 for their generous donation of Q-Best™ proprietary Ubiquinone for this case study, and to (2) Kaneka Nutrients L.P., 6161 Underwood Rd, Pasadena, TX 77507-1033, for their generous donation of proprietary Ubiquinol, for this case study.

References


1. Badmaev V, Majeed M, Norkus E, Piperine, an alkaloid derived from black pepper increases serum response of beta carotene during 14 days of oral beta carotene supplementation. Nutr. Res. (1999) 19(3): 381-388.
2. Badmaev V, Majeed M, Prakash L, Piperine derived from black pepper increases the plasma levels of coenzyme q10 following oral supplementation. J Nutr Biochem. 2000 Feb 1;11(2):109-113.
3. Barbiroli, B., et al.  Coenzyme Q10 improves mitochondrial respiration in patients with mitochondrial cytopathies. An in vivo study on brain and skeletal muscle by phosphorous magnetic resonance spectroscopy.  Cell Mol Biol.  43(5):741-749, 1997.
4. Bargossi, A. M., et al.  Antioxidant effects of exogenous ubiquinone (Q10) in high level endurance runners.  Free Radicals and Antioxidants in Nutrition.  1993:63-74.
5. Bonetti A, Solito F, Carmosino G, Bargossi AM, Fiorella PL. Effect of ubidecarenone oral treatment on aerobic power in middle-aged trained subjects. J Sports Med Phys Fitness. 2000 Mar;40(1):51-7.
6. Cooke M, Iosia M, Buford T, Shelmadine B, Hudson G, Kerksick C, Rasmussen C, Greenwood M, Leutholtz B, Willoughby D, Kreider R. Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. J Int Soc Sports Nutr. 2008 Mar 4;5:8.
7. Cornell University Age Calculator @: http://www-users.med.cornell.edu/~spon/picu/calc/agecalc.htm
8. Dhanasekaran M, & Ren J, The Emerging Role of Coenzyme Q10 in Aging, Neurodegeneration, Cardiovascular Disease, Cancer and Diabetes Mellitus, Current Neurovascular Research, 2(5): 447- 59, December 2005.
9. Ernster L, Dallner G: Biochemical, physiological and medical aspects of ubiquinone function. Biochim Biophys Acta, 1995; 1271: 195-204.
10. Gaby, Alan R, MD, Coenzyme Q10 – Textbook of Natural Medicine, NY: Churchill Livingstone, pp 663-71, 1999.
11. Gökbel H, Gül I, Belviranl M, Okudan N. The effects of coenzyme Q10 supplementation on performance during repeated bouts of supramaximal exercise in sedentary men. J Strength Cond Res. 2010 Jan;24(1):97-102.
12. Lenaz, G., et al.  Oxidative stress, antioxidant defenses and aging.  Biofactors.  8:195-204, 1998.
13. Papucci, L., et al.  Coenzyme Q10 prevents apoptosis by inhibiting mitochondrial depolarization independently of its free radical-scavenging property.  J Biol Chem.  20
14. Quinzii CM, DiMauro S, Hirano M. Human coenzyme Q10 deficiency. Neurochem Res. 2007 Apr-May;32(4-5):723-7. Epub 2006 Nov 10. Review.
15. Rosenfeldt FL, Pepe S, Ou R, Mariani JA, Rowland MA, Nagley P, Linnane AW. Coenzyme Q10 improves the tolerance of the senescent myocardium to aerobic and ischemic stress: studies in rats and in human atrial tissue. Biofactors. 1999;9(2-4):291-9.
16. World Association of Veteran Athletes (WAVA) Age-grading calculator 2006 (updated 2010) @: http://www.howardgrubb.co.uk/athletics/wmalookup06.html

Source(s) of Funding


None.

Competing Interests


None.

Disclaimer


This article has been downloaded from WebmedCentral. With our unique author driven post publication peer review, contents posted on this web portal do not undergo any prepublication peer or editorial review. It is completely the responsibility of the authors to ensure not only scientific and ethical standards of the manuscript but also its grammatical accuracy. Authors must ensure that they obtain all the necessary permissions before submitting any information that requires obtaining a consent or approval from a third party. Authors should also ensure not to submit any information which they do not have the copyright of or of which they have transferred the copyrights to a third party.
Contents on WebmedCentral are purely for biomedical researchers and scientists. They are not meant to cater to the needs of an individual patient. The web portal or any content(s) therein is neither designed to support, nor replace, the relationship that exists between a patient/site visitor and his/her physician. Your use of the WebmedCentral site and its contents is entirely at your own risk. We do not take any responsibility for any harm that you may suffer or inflict on a third person by following the contents of this website.

Reviews
44 reviews posted so far

Dear Dr. Shahid, Thank you for your excellent review and positive comments.You may also review the revised version to confirm that your ideas were collectively applied @ http://www.webmedcentral.com/a... View more
Responded by Dr. Bill Misner on 11 Dec 2011 04:48:33 PM GMT

Review
Posted by Prof. Vaclav Vetvicka on 03 Dec 2011 10:14:57 PM GMT

Dear Dr. Sukhbir Shahid, Your suggestions are well received! Two colleagues also made similar comments. May I request another review of the revised version of this paper to determine if I fulfilled yo... View more
Responded by Dr. Bill Misner on 09 Dec 2011 11:28:03 PM GMT

Dear Dr. Gupta, There are 34 esteemed scholars who have reviewed this "Inconclusive" Case Report, none were discourteous nor poorly informed regarding the enormously complex mechanisms involved requir... View more
Responded by Dr. Bill Misner on 27 Nov 2011 11:05:53 PM GMT

Dear Dr. Herchline, I appreciate your review-comments, in that getting a passable "5" rating may be rare from you for a case report. I think you might be a good future case-study subject for placebo... View more
Responded by Dr. Bill Misner on 23 Nov 2011 04:17:52 AM GMT

Dear Dr. Salvatore Chirumbolo, Thank you for your esteemed review. We do need more data with more subjects all ages. We must also find a method to objectively determine if blood parameters reflect cel... View more
Responded by Dr. Bill Misner on 21 Nov 2011 07:16:30 PM GMT

Dear Dr. Oluyomi S Adeyemi, Your comments are well received, thank you for your esteemed review of this paper. Well done! Bill Misner PhD... View more
Responded by Dr. Bill Misner on 16 Nov 2011 05:48:36 PM GMT

Dear Professor Valcinir Bedin, Thank you again for your valuable comments, all have indeed shaped both the quality and significant finidng/though limited tp the single-subject in this Case Report. As ... View more
Responded by Dr. Bill Misner on 15 Nov 2011 05:50:06 PM GMT

Dear Dr. Aswini Dutt. R, I completely agree! As a Case Report can at most beg the question, we know that raising serum CoQ10 may or may not reach cells responding with increase energy output. This is... View more
Responded by Dr. Bill Misner on 09 Nov 2011 07:26:22 PM GMT

Dear Dr. Giriraj T Kulkarni, I deeply appreciate your comments and this esteemed review. Bill Misner PhD... View more
Responded by Dr. Bill Misner on 08 Nov 2011 09:33:16 PM GMT

Second review
Posted by Dr. Karthikkumar Venkatachalam on 02 Nov 2011 06:25:18 AM GMT

Dear Mr. Karthikkumar Venkachalam, Thank you for this review...The original manuscript was not submitted with this error you reported and this error in order to be corrected, I will contact WebMedCent... View more
Responded by Dr. Bill Misner on 02 Nov 2011 06:03:58 PM GMT

Dear Dr. Balendra Pratap P Singh, Thank you for your patience and now three scholarly reviews on this revised version of a Case Report. Very well done, Bill Misner PhD... View more
Responded by Dr. Bill Misner on 02 Nov 2011 03:06:57 AM GMT

Second review of a case report
Posted by Prof. Michael Zanovec on 01 Nov 2011 08:46:04 PM GMT

Dear Professor Zanovec, Thank you for investing a 2nd review of this case report, well done, sir. Bill Misner PhD... View more
Responded by Dr. Bill Misner on 01 Nov 2011 08:53:26 PM GMT

Improved
Posted by Dr. Dejan Stevanovic on 01 Nov 2011 11:07:57 AM GMT

Dear Dr. Stevonovic, I am very pleased to have read your review and comments. I am an example of a researcher who has (per your words) published a "Not-Perfect" paper. You have been very very helpful ... View more
Responded by Dr. Bill Misner on 01 Nov 2011 03:47:48 PM GMT

Dear Dr. Bilgin Kadri Aribas, I send my sincere enthusiastic appreciation for your review posted here. Bill Dr. Bill Misner PhD... View more
Responded by Dr. Bill Misner on 10 Jan 2012 03:25:23 PM GMT

a well-written case study, but nothing conclusive.
Posted by Prof. Feng Feng on 07 Nov 2011 07:19:01 PM GMT

Professor Feng Feng, Thank you for your esteemed review. Today, 11-8-11, this paper was revised and as you noted, it also states without excuse that a single-subject case report is inconclusive, thoug... View more
Responded by Dr. Bill Misner on 08 Nov 2011 04:33:58 PM GMT

Dr. Constantino Ledesma-Montes, Thank you for your esteemed review and helpful comments on this article, sir. Bill Misneer... View more
Responded by Dr. Bill Misner on 08 Dec 2012 05:46:40 PM GMT

Dear Dr. Constantino Ledesma-Montes, Thank you for posting your review of this Case Report. I agree with your final comments. The gain above washout-base without consuming oral dose of 2.28% performan... View more
Responded by Dr. Bill Misner on 08 Nov 2011 04:29:18 PM GMT

revision
Posted by Mr. Santiago Perez Lloret on 31 Oct 2011 02:35:18 PM GMT

Dear Mr. Santiago Perez Lloret, Sir, thank you for this review with your comments. As you likely know, oral dose CoQ10 is poorly absorbed, and as my paper states, food sources are not high in terms of... View more
Responded by Dr. Bill Misner on 31 Oct 2011 04:27:49 PM GMT

Dear Dr. Ahmed A Khalil, Thank you for your review and well-designed suggestions. I have copied and pasted them all in my notes to use with the final rewritten version for final submission on this com... View more
Responded by Dr. Bill Misner on 31 Oct 2011 04:14:36 PM GMT

Professor Macello Iriti, Thank you for your esteemed review of this "Case Report." When the final draft is submitted, I will move the discussion section behind the conclusions section. I hope you noti... View more
Responded by Dr. Bill Misner on 31 Oct 2011 04:04:06 PM GMT

Professor Bedin, Thank you for your review of this "Case Report." Your previous scholarly comments on the former "Case Study" version of this paper definitively improved the quality significantly. I ... View more
Responded by Dr. Bill Misner on 30 Oct 2011 04:31:08 PM GMT

Dear Dr. Kulkami, Thank you for your review of my Case Report. With your science background in drug delivery, this credible review is very highly valued. Bill Misner PhD... View more
Responded by Dr. Bill Misner on 29 Oct 2011 05:50:34 PM GMT

Dear Dr. Ekta Menghani, Thank you for a brilliant review of this paper. Your experiences observing and reporting plant-generated properties is relevant to why hydrogen-carrying properties of between U... View more
Responded by Dr. Bill Misner on 29 Oct 2011 04:38:28 PM GMT

Dr. Abu Dzarr, Thank you for reviewing my paper and sharing your concerns. Bill Misner PhD ... View more
Responded by Dr. Bill Misner on 29 Oct 2011 04:06:58 AM GMT

Dr. Herchline, Thank you for spending your time to review this paper. I appreciate your review commentary. Bill Misner PhD... View more
Responded by Dr. Bill Misner on 29 Oct 2011 02:32:16 AM GMT

The absence of blinding is a problem
Posted by Dr. Jacob Puliyel on 28 Oct 2011 06:26:31 PM GMT

Dr. Puliyel, Thank you for your comments and critical review. Blinding would have been performed including times listed from each 90-day period. The facts are simply that had we done blinding with sep... View more
Responded by Dr. Bill Misner on 29 Oct 2011 02:30:26 AM GMT

Professor Shenkman, Thank you for reviewing my case report. Your scholarly comments are deeply appreciated. Please include me as a scholarly reviewer of any articles you publish on WebMedCentral...As ... View more
Responded by Dr. Bill Misner on 28 Oct 2011 03:38:52 PM GMT

Dr. Nwankwo, Thank you for reviewing my case report. Your comments are deeply appreciated. Bill Misner PhD... View more
Responded by Dr. Bill Misner on 28 Oct 2011 03:35:50 PM GMT

Dr. Hmadcha, Thank you for reviewing my case report. Your comments are deeply appreciated. Bill Misner PhD... View more
Responded by Dr. Bill Misner on 28 Oct 2011 03:34:59 PM GMT

Dr. BK Aribas, Thank you for reviewing this case report. Your comments are deeply appreciated. Bill Misner PhD... View more
Responded by Dr. Bill Misner on 28 Oct 2011 03:34:19 PM GMT

Dr. Karthikkumar Venkatachalam, Thank you for reviewing my case report. Your comments are deeply appreciated. Bill Misner PhD... View more
Responded by Dr. Bill Misner on 28 Oct 2011 03:33:15 PM GMT

Dr. Singh, Thank you for your response and helpful comments. This review is most welcomed. Bill Misner PhD... View more
Responded by Dr. Bill Misner on 29 Oct 2011 02:16:26 AM GMT

Dr. Stevanovic, Thank you for your critical review and well-thought comments. Once again I completely agree with your suggested order for case reporting. I have conducted many single-case "experiments... View more
Responded by Dr. Bill Misner on 28 Oct 2011 03:30:44 PM GMT

Dr. Rao, Thank you for presenting an excellent review with comments I agree completely. I will add the following thoughts that I have been reluctant to share until now, since I conclude that your revi... View more
Responded by Dr. Bill Misner on 30 Oct 2011 04:24:22 PM GMT

Dr. Kulkami, Thank you for your review and comments. Bill Misner... View more
Responded by Dr. Bill Misner on 08 Dec 2012 05:44:50 PM GMT

Coenzyme Q-10 and Endurance Performance
Posted by Dr. Thomas Herchline on 20 Oct 2011 11:38:02 PM GMT

Review of case study
Posted by Mr. Michael Zanovec on 20 Oct 2011 06:15:48 PM GMT

Micahel Zanovec, I hope for your review of the revised version entitled, Coenzyme Q-10 Effects Endurance Performance - A Case Report Bill Misner PhD ... View more
Responded by Dr. Bill Misner on 29 Oct 2011 02:36:03 AM GMT

Comments
1 comment posted so far

Case Report Limits from the Author (Avoid Abuse) Posted by Dr. Bill Misner on 04 Dec 2011 05:45:38 AM GMT

Please use this functionality to flag objectionable, inappropriate, inaccurate, and offensive content to WebmedCentral Team and the authors.

 

Author Comments
0 comments posted so far

 

What is article Popularity?

Article popularity is calculated by considering the scores: age of the article
Popularity = (P - 1) / (T + 2)^1.5
Where
P : points is the sum of individual scores, which includes article Views, Downloads, Reviews, Comments and their weightage

Scores   Weightage
Views Points X 1
Download Points X 2
Comment Points X 5
Review Points X 10
Points= sum(Views Points + Download Points + Comment Points + Review Points)
T : time since submission in hours.
P is subtracted by 1 to negate submitter's vote.
Age factor is (time since submission in hours plus two) to the power of 1.5.factor.

How Article Quality Works?

For each article Authors/Readers, Reviewers and WMC Editors can review/rate the articles. These ratings are used to determine Feedback Scores.

In most cases, article receive ratings in the range of 0 to 10. We calculate average of all the ratings and consider it as article quality.

Quality=Average(Authors/Readers Ratings + Reviewers Ratings + WMC Editor Ratings)