Open Access Biomedical Publisher Using Post Publication Peer Review
Associate Professor China Agricultural University
No. 2, Yuan Ming Yuan West Road, Haidian District China 100193
Prof. Wang has published 8 first or corresponding-author papers in good to excellent journals after she started as an independent investigator. She has five grants funded by the National Science Foundation of China and received a national research award (the highest honor for young researchers) in the past 5 years. Prof. Wang is proficient in both English and Russian languages and writes extremely well and fast. She is well connected with many other leading universities and research institutes inAmerica,GermanyandChina. In addition, she has a strong sense of responsibility and always willing to take on challenges.
Visiting Assistant Professor, 2010-2011, The University ofChicago,IL,USA
Associate Professor, 2006-present, ChinaAgricultural University,Beijing,China
My research deals with the molecular mechanisms of envelope viruses entering host cells, focusing on the tertiary structure conformations and interactions of important proteins during virus entrance. The present results offer the possibility of designing a relatively broad-spectrum class of antiviral mix-infection inhibitors. A Chinese patent has been awarded. Part of the result was published in Virology, 2011.
Refereed Journal Papers and Corresponding author:
Wang, X.J., Patenode, C., Roizman, B. The US3 protein kinase of HSV-1 cycles between the cytoplasm and nucleus and interacts with PDCD4 to block apoptosis. Proc Natl Acad Sci USA, 2011, 108(35), 14632-6.
Wang, X.J., * Li, C.G., Chi, X.J., Wang, M. Characterisation and evaluation of antiviral recombinant peptides based on the heptad repeat regions of NDV and IBV fusion glycoproteins. Virology, 2011, 416 (1-2), 65-74.
Wang, X.J. * Chi, X.J., Wang, M. Structural characteristics and antiviral activity of multiple peptides derived from MDV glycoproteins B and H. Virology Journal, 2011, 8, 190-203.
Wang, X.J. * Heat-shock protein 70 is associated with the entry of Marek’s disease virus into cells. Acta Virologica, 2011, 55, 189-94.
Li, H., Li, X., Lu, Y., Wang, X.J., Zheng, S.J.. Staphylococcus sciuri exfoliative toxin C is a dimer that modulates macrophage functions. Canadian Journal of Microbiology, 2011, 57(9), 722-9.
Wang, X.J. * The molecular mechanism of herpesvirus membrane fusion, Progress in Biochemistry and Biophysics, 2010, 37 (6), 583-88. (review article)
Wang, X.J. and Wang, M. The molecular mechanism of class II enveloped viruses membrane fusion, Progress in Biochemistry and Biophysics, 2007, 34 (7), 682-86. (review article)
Wang, X.J., Bai, Y.D., Zhang, G.Z., Zhao, J.X., Wang, M., and Gao, G.F. Structure and function study of paramyxovirus fusion protein heptad repeat peptides, Archives of Biochemistry and Biophysics, 2005, 436 (2), 316-322.
Wang, X.J., Zhang, G.Z., Zhao, J.X., and Wang, M. Interacting domains of the HN and F proteins of paramyxovirus, Chinese Science Bulletin, 2005, 50 (20), 2231-2234.
Wang, X.J., Zhu, D.B., Zhang, G.Z., Bai ,Y.D., and Wang, M. Construction and expression of correlative genes with membrane fusion of paramyxovirus, Progress in Biochemistry and Biophysics, 2005, 32 (3), 228-34.
Wang, X.J., Xu, Y.H., Cole ,D.K., Lou, Z.Y., Liu, Y.W., Rao, Z.H., Wang, M., and Gao, G.F. Biochemical, biophysical and X-ray crystallographic analyses of the fusion core of Sendai virus F protein, Acta Crystallographica Section D, 2004, 60 (9), 1632-1635.
Wang, X.J., Zhang, W.H., Wang, M., and Gao, G.F. The Molecular mechanism of enveloped virus-cell membrane fusion, Progress in Biochemistry and Biophysics, 2004, 31 (6), 482-491. (review article)
Wang, X.J., Liu, C., Bai, Y.D., Xia, C., and Wang, M. Cloning and sequence analyses of ovine IFN-Tau, Chinese Journal of Veterinary Medicine, 2004, 40(8), 3-5.
Wang, X.J, Xia, C. and Wang, M. Progress in molecular biology of IFN-Tau, Chinese Journal of Veterinary Medicine, 2004, 40(2), 36-37. (review article)
Bai, Y.D., Wang, X.J., Zhang, C., Han, C.L., Wang, M. Clone and expression of heptad repeat of fusion glycoprotein from Canine Distemper Virus, Chinese Journal of Veterinary Medicine, 2005, 40(9), 6-8.
Qin, Z.M. and Wang, X.J. Isolation and SDS-PAGE analysis of Infectious Bronchitis Virus, Shandong Poultry, 1999, 5, 4-6.
Xiao-Jia Wang, Ming Wang. HR2-mimical codes and proteins and their applications. Zl 200610144153 (China patent)
Xun Suo, Xiao-Jia Wang, Xian-Yong liu, Li-Li Hao, Wen-Chao Yan, Hong-Yan Wang, Jia-Nan Li. Novel application of Coccidian. ZL 200710064924.8, PCT/CN2008/000621 (International PCT patent)
Ming Wang, Xiao-Jia Wang. Detection techniques and kit of coccidian drug resistance. 2010100801808 (China patent)
Xiao-Jia Wang, Ming Wang. Novel peptides against virus mix-infections. 2010101218301 (China patent)
It is my hope to organize the meetings for younger researchers in the chosen field (more difficult); or to transmit the up-dated scientific proceedings for each others by internet (easier to catch up)
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