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Tenure-Track Assistant Professor, Center for Cell and Gene Therapy Baylor College of Medicine
One Baylor Plaza, Houston TX United States of America 77030
Tenure-Track Assistant ProfessorDepartment of Pathology & ImmunologyCenter for Cell and Gene TherapyBaylor College of MedicineTexas Children’s HospitalEducation1997-2002: Ph.D. in Molecular Immunology,Department of Microbiology and Immunology NanjingMedica University, Nanjing, China1988-1993: B.S. in Medicine Peking University Health Science Center(Previous Beijing Medical University), Beijing, China
Training and Working Experience:2010-Tenure-Track Assistant Professor, Department of Pathology & Immunology Center for Cell and Gene TherapyBaylor College of Medicine, Houston, TX,2007-2010: Instructor, Department of Pathology & ImmunologyCenter for Cell and Gene Therapy Baylor College of Medicine, Houston, TX,2003-2007: Postdoctoral Research Associate Center for Cell and Gene Therapy Baylor College of Medicine, Houston, TX,2002-2003: Postdoctoral Research Associate Chemistry and Immunotherapy Research Center Department of Pathology & Laboratory Medicin Univ.of Texas at Houston, Medical School, Houston, TX1993-1997: Assistant Member National Immunization ProgramJiangsu Center for Disease Control and Prevention, Nanjing, China
Cancer immunotherapy, including T cell therapy, cancer vaccine, virus therapy, antibody therapy vaccines for infectious diseases, such as AIDS.
Teaching experience 2010-2011 : Lecturer in “Cellular Vaccines”, CAGT Graduate School Course2009-2010 : Lecturer in “Cellular Vaccines”,CAGTGraduateSchoolCourse2008-2009 : Lecturer in “Cellular Vaccines”,CAGTGraduateSchoolCourseJournal ReviewerMolecular Therapy Immunology and Cell BiologyAbstract reviewer for conference2011 ASGCT 14th Annual Meeting, May 18-21, 2011, Seattle, Washington.Patent1.Co-inventor, 20060292119, Dec 28, 2006. Modulation of negative immune regulators and applications for immunotherapy.2.1st inventor, pending, 2010. Inhibiting Retinoic Acid Production for HIV vaccination.Award1.2011 National CFAR New Investigator Award2.2009 Asia-Pacific Conference of Tumor Biology and Medicine, Excellent Paper Award3.AACR Annual Meeting 2007 - Aflac,IncorporatedScholar-in-Training AwardSelected Authored Publications1.Hong BX, Song XT (co-1st author), Jones, L, Rollins L., Huang, XF, Chen SY. Mucosal and systemic anti-HIV immunity controlled by A20 in Dendritic cells. J Clin Invest. 2011 Feb 1;121(2):739-512.Song XT (corresponding author), Turnis M, Zhu W, Zhou XO, Hong BX, Rollins L, Chen SY, Rooney CM, Gottschalk SM. A Th1-inducing Adenoviral vaccine for boosting adoptive transferred T cells. Molecular Therapy 2011 Jan 19(1):211-7.3.Turnis ME, Song XT, Bear A, Foster AE, Gottschalk S, Brenner MK, Chen SY, Rooney CM. Absence of IRAK-M in murine dendritic cells results in improved migration, longevity, and Th1-skewed function. J Immunol. 2010 Oct. 1 ;185(7) :4223-4232.4.Fu XP, Tao LH, Rivera A., Williamson S, Song XT, Ahmed N, Zhang X. A simple and sensitive method for measuring tumor-specific T cell cytotoxicity. PLoS One 2010 Jul 29 ;5(7) :e118675.Hong BX, Ren WH, Song XT, Evel-Kabler K, Chen SY, Huang XF. Human SOCS1 Controls Immunostimulatory Activity of Monocyte-derived Dendritic Cells. Cancer Res 2009 Oct 15;69(20):8076-846.Song XT, Evel-Kabler K, Rollins L, Aldrich M, Huang XF, Chen SY. A20 is an antigen presentation attenuator, and its inhibition overcomes regulatory T cell-mediated suppression. Nat Med 2008 Mar 02; 14(3): 258-265.7.Song XT, Aldrich M, Chen SY. SOCS1 inhibition strategy to enhance anti-HIV vaccination. Expert Rev Vaccines. 2006 Aug; 5(4):495-503.8.Song XT, Evel-Kabler K, Rollins L, Aldrich M, Gao F, Huang XF, Chen SY. An Alternative and Effective HIV Vaccination Approach Based on Inhibition of Antigen Presentation Attenuators in Dendritic Cells. PLoS Med. 2006 Jan 3; 3(1):e11.9.Evel-Kabler K, Song XT, Aldrich M, Huang XF, Chen SY. SOCS1 restricts dendritic cells’ ability to break self tolerance and induce antitumor immunity by regulating IL-12 production and signaling. J Clin Invest. 2006 Jan; 116(1):90-100.10.Planque S, Bangale Y, Song XT, Karle S, Taguchi H, Poindexter B, Bick R, Edmundson A, Nishiyama Y, Paul S. Ontogeny of proteolytic immunity: IgM serine proteases. J Biol Chem. 2004 Apr 2;279(14):14024-32. (2006 impact factor 5.808)11.Zhu Y, Song XT, Guan XH, Feng ZQ. Cloning and sequence Analysis of the variable region gene of Monoclonal antibody NP48 of Schistosoma Japonicum. Chinese Journal of Schistosomiasis control. 2004.0312.Song XT, Feng ZQ, Wang ZM, Qiu ZN, Li YQ, Guan XH, Huang HL. Construction and expression of single chain Fv gene of anti-idiotypic monoclonal antibody NP30 of Schistosoma Japonicum. China Journal Parasitology and Parasite Disease. 2002; 20(3): 152-4.13..Song XT, Feng ZQ, Guan XH. Cloning and Sequence Analysis of the Heavy Chain Variable Region Gene of Monoclonal Anti-idiotypic Antibody NP30 of Schistosoma Japonicum. Chinese Journal of Schistosomiasis Control. Chinese Journal of Schistosomiasis Control. 2002.01.14..Song XT, Feng ZQ, Guan XH. Cloning and Sequence Analysis of the Light Chain Variable Region Gene of Monoclonal Anti-idiotypic Antibody NP30 of Schistosoma Japonicum. China Journal Parasitology and Parasite Disease. 2000-10, vol.18, 5:259.15..Song XT, Feng ZQ, Guan XH. The Current Research Progress on the Role of IL-12 in Anti-Schistosoma Immunity. Chinese Journal of Schistosomiasis Control. 2000. 06. 16.Song XT, Feng ZQ. Immunopathology of Echinococcosis. Foreign Medical Sciences, 1998, 25(6).Zhou L, Bi C, Diao ND, Ma FB, Song XT. A Serological Survey on Tetanus Antibody 17.Level of Normal Populations in Jiangsu Province. Chinese Journal of Vaccines and Immunization. 1999.01.
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