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- Gastroenteric-induced Bilateral Paroxysmal Hemicrania
Abstract: BACKGROUND: Functional gastrointestinal disorders; i.e., irritable bowel syndrome, cyclic vomiting, gastro-esophageal reflux and dyspepsia, are more common in individuals with migraine. Autonomic manifestations of migraine, and less commonly of paroxysmal hemicranias (PH), include those of gastrointestinal (GI) tract o..
- Vaginal Birth After Three Previous Caesarean Sections: A Case Report
Abstract : BACKGROUNDCaesarean delivery is the most common major obstetric operation carried out for maternal and or fetal indications. While most obstetricians will permit vaginal birth after a prior caesarean, those with 2 or more previous caesarean sections are usually delivered abdominally because of increased risk of uterine..
- Ionotropic Gelation Technique For Microencapsulation Of Antihypertensive Drug
Abstract: Micropellets of verapamil hydrochloride were formulated by ionotropic gelation technique using sodium alginate, hydroxy propyl methyl cellulose and hydroxy propyl cellulose. Prepared micropellets were evaluated for flow behaviour, drug entrapment efficiency, in-vitro dissolution and stability studies, including scanni..
- Post Hemorrhagic Hemicrania Continua In A Patient With Orgasmic Paroxysmal Hemicrania
Abstract: BACKGROUND: In its classic form sentinel headache heralds an underlying intracranial aneurysm near rupture. Headache related to sexual activity is normally benign and does not represent a sentinel headache to ulterior intracranial bleeding. Hemicrania continua is a primary headache only exceptionally precipitated by ac..
- Influenza: The 2009 H1N1 Pandemic And Antiviral Treatment Options
Abstract : Purpose. To provide an overview of the 2009 H1N1 influenza pandemic and antiviral treatment options for influenza. Summary. Influenza infection causes significant morbidity and mortality every year. The high mutation rate and segmented nature of influenza virus genome gives rise to high genetic variability which enable..
- Does The Cornell Medical Index Measure Real Or Perceived Occupational Health?
Abstract : Background. The Cornell Medical Index (CMI) has been widely used to measure health indicators. Although its effectiveness in detecting subjective pathologies has been demonstrated, it has not been evaluated as an epidemiological screening test to detect pathologies contrasted with clinical records. Methods. A cohort sa..
- Infantile Pulmonary Hemosiderosis
Abstract : Pulmonary hemosiderosis in infants (< 1 year of age) is a syndrome characterized by pulmonary hemorrhage and hemosiderin-laden macrophages. As there are multiple incompletely understood etiologies re..
- The US Healthcare System: Current Issues And Proposal For Further Reform
My opinion: AbstractThis article discussed the strength and limitations of the current US healthcare system and provided some preliminary reform proposals. The US health system spending is the highest around the world, yet its performance is disappointing. The issues of the US health system include ideological clash on health care..
- Optimization Of Propranolol Hydrochloride Controlled Release Matrix Tablet Using Factorial Design
Abstract: Purpose: The objective of this study was to prepare Propranolol Hydrochloride controlled release matrix tablets and to investigate the effect of the polymer blends and the polymer concentration on drug release.Method: Propranolol Hydrochloride controlled release matrix tablets were prepared by direct compression techni..
- Refractory Hypokalemia- From Ectopic Adrenocorticotropic Hormone Secreting Thymic Tumor
Abstract : Ectopic Adrenocorticotropic (ACTH) secreting tumors are unusual causes of Cushing’s syndrome. Etiologies include small cell lung cancer (SCLC), medullary thyroid carcinoma and pheochromocytoma (1, 2, and 3) or carcinomas (such as hypernephromas, colon cancer, and paragangliomas). Neuroendocrine tumors of thymus a..
- Googles Eye Shield & Evaporative Dry Eye
My opinion: Evaporative dry eye and aqueous tear-deficient dry eye are the two major sub-types of dry eye1. Though self-reported eye complaints and ocular surface alterations have been reported to have a high prevalence (72.3%) in operating room (OR) personnel2, incidence of dry eye (evaporative or aqueous tear-deficient) in OR pe..
- Sneeze-vector And Sexually Transmitted Vaccines
Hypothesis: Intra-nasal vaccine delivery (e.g. Flumist) has become a popular alternative to injections: just as naturally occurring viruses can enter the body through the respiratory system, so can artificially attenuated or inactivated viruses, or vaccines. The ability of vaccine strains to act effectively after entering the body..
- Primary Soft Tissue Giant Cell Tumor Of Neck
Abstract : Soft tissue giant cell tumor (GCT-ST) of low malignant potential is an uncommon neoplasm, considered as the soft tissue counterpart of giant cell tumor of bone. We report a rare case of soft tissue Giant Cell Tumour of Neck in a 61 years old female with swelling in left side of neck, spontaneous in onset. Incisional bi..
- Incidence of Strongyle infection in cattle and pig with relevance to rainfall in Meghalaya
Abstract: A Study was conducted to know the effect of meteorological parameters on strongyle infection in cattle and pig in Meghalaya. Faecal samples, collected from three Govt. farms during years 2001 – 2002, were screened for the presence of strongyle parasitic egg. Incidence of strongle infection in relation to met..
- Reduction of ovariectomy-induced bone loss in rats by menaquinone-4, cholecalciferol, and (n-3) polyunsaturated fats
Abstract : Menopause and ovariectomization both lead to a rapid loss of bone mineralization. Conflicting reports exist concerning the ability of menaquinone-4, a form of vitamin K routinely used in Japan, to suc..
- Dental Analgam: Myth vs. reality
Abstract : Dental amalgam is a mixture of metals such as silver, copper and tin, in addition to mercury, which chemically binds these components into a hard and stable substance.Amalgam has been widely used to r..
- A Sensible Approach to Monitoring Trials: Finding effective solutions in-house
Abstract : There has been a trend over recent years towards the use of expensive contract organisations (1, 2)to monitor trials and clinical researchers describe a shift from a protocol or disease related discussion and guidance style of monitoring to a tick box checking process carried out by less experienced monitors. Alongside..
- A Sperm Chromatin Structure Assay (scsa): Background Snalysis Of Azoospermic Semen, Validity Of Snap Freezing Semen Prior To Assay, And The Between-ejaculate Variability Seen With Donors
Abstract : The sperm chromatin structure assay (SCSA) was applied to human sperm, and factors affecting its routine operation investigated. The findings indicated that (a) non-sperm cells in semen can contribut..
- Absence Of Oestrus In H.sapiens ; Review Of Possible Causes And Suggested Explanation
Abstract : One of the peculiarities of our species is that we have a menstrual cycle rather than an oestrus cycle.When women ovulate they do not have the extreme proactive sexual behavior which is found in the great majority of placental mammals.Oestrus itself is confined to the placental mammals.Vertebrates such as fish, amphibi..
- The Knowledge And Skills Of Surgical Foundation Year One Doctors In A Teaching Hospital In The UK: A Review And Results Of A Survey
Abstract : Introduction:Junior doctors had acquired knowledge and skills in the past using weekly specialty based teaching sessions and on the job learning.They currently learn on the job as before (with the restraints of less working hours). However, generic hospital wide teaching programmes have replaced the specialty teaching ..
- Safe Treatment of Hypertension to Guideline Targets in Nonagenarian Vascular Dementia
Introduction: More than 60 % of those over the age of 70 have hypertension, yet two-third receive no treatment or are not treated to meet current hypertension guideline criteria (≤ 140/90 mm Hg), even in case of secondary prevention [1]. Although there is evidence that blood pressure lowering in older adults effectively reduces c..
- True Day Case Laparoscopic Cholecystectomy: Safety And Feasibility In A District General Hospital In The UK
Abstract : Introduction:A prospective audit was undertaken of true day case laparoscopic cholecystectomies performed by a single surgeon in a DGH. The audit aims primarily to ascertain the outcome of the operation and patients’ satisfaction with the experience. Data was analysed to find out factors that led to overnight adm..
- Sex In Common Pet Turtles
Abstract : With the growing market for pet turtles, veterinarians are confronted with new demands. Owners or breeders of turtles generally know that these species are temperature-dependent in terms of sex determination, but lack specific knowledge on how it works. Furthermore, they need advice on how to control incubation conditi..
- Asthmatic patients may complain more often about eventual depressive symptoms than other chronic patients
Abstract : Introduction: Recently published researches point out that asthmatics seem to be distinguished by a psychological profile described as halfway between patients with mood disorders or anxiety and gener..
- A familiar case of progressive relief of seasonal allergy-like symptoms during jaundice
Abstract : Two sisters 18 and 20 years old had been suffering from rhinorrhea, sneezing, and nasal obstruction in May and June for 10 years. Every year, after the reach of nasal symptomatic peak in May, the above mentioned symptoms relieved progressively, whereas in the meantime bilirubin level and jaundice intensity increased. J..
- The Knowledge And Skills Of Surgical Foundation Year One Doctors In A Teaching Hospital A Review And Results Of A Survey
Abstract : Introduction: Junior doctors had acquired knowledge and skills in the past using weekly specialty based teaching sessions and on the job learning. They currently learn on the job as before (with the restraints of less working hours). However, generic hospital wide teaching programmes have replaced the specialty teachin..
- Antiinflammatory, antimicrobial and immunomodulatory properties of Lactobacillus casei against Enteropathogenic Escherichia coli
Abstract: Purpose: Immunomodulatory as well as in vivo antimicrobial properties of Lactobacillus casei were investigated. L. casei was administered orally in Wistar rats. Methods: Enteropathogenic Escherichia c..
- Thoracic Spine Fractures Following Motorcycle Accidents in Nigeria
Abstract : Background: Thoracic spine (T1-T12) fracture following motorcycle accident (MCA) is not uncommon injury and the topic has not been reported on in Nigeria. Objective: The aim of this study is to report on the demographic pattern of presentation and the short term neurologic outcome of conservative treatment of thoracic ..
- Fluid Therapy in Children: A Review
Abstract : Fluid therapy restores circulation by expanding extracellular fluid. Intravenous fluid therapy for children with volume depletion should first restore extracellular volume with measured infusions of isotonic saline followed by defined, appropriate maintenance therapy to replace physiological and pathological losses acc..
- Hyperbolic Relationship between Blood Pressure and Body Mass Index in a Nigerian Adolescent Population
Abstract: ObjectiveHypertension is a leading killer in the world, and is known to begin in childhood/adolescence, and to track into adulthood. Traditionally, blood pressures are said to be associated positively with body mass index (BMI), even in adolescents. This study investigated the relationship between blood pressures and ..
- Paradigms on Biogeneric Drugs - Some views
Article: The paradigm claimed by brand-name biopharmaceutical manufacturers that “the process is the drug” hence the need for performing clinical trials for introducing biogenerics, is scientifically unsound. It comes to no surprise then, that brand-name biological manufacturers all of a sudden are tremendously conc..
- The Role of Patient Involvement in Practice Based Commissioning within the UK's National Health Service
Abstract: Over the past decade there has been mounting debate about the desirability of public and patient involvement in the commissioning of health services in the UK. This issue has arisen partially due to the National Health Service management moving from a system control by health practitioners to that of a devolved manager..
- Insulin-overdose- A Potential Trigger of Ventricular Fibrillation with Takotsubo Cardiomyopathy?
Abstract : A 46 years-old diabetic man lost consciousness because of an insulin-overdose (Glasgow Coma Scale 3, blood-glucose 1.5mmol/L). He regained consciousness after infusion of glucose 5% 100ml/10minutes (G..
- Combatting Human African Trypanosomiasis in Uganda within a decentralized context
My opinion: Combatting Human African Trypanosomiasis in Uganda within a decentralized contextWhile T.b rhodesiense continues to spread from its traditional focus in the South and East, case of T.b gambiense continue to be recorded in north-western Uganda in the West Nile Region. Of particular worry is that these foci are currentl..
- What do POPs require of Children and Environmental Health (CEH) strategy?
Abstract : The European Ministers’ CEH declaration in Budapest 2004 recognised children as specially vulnerable and not ‘little adults’ [1]. It expressed concern over potential toxicity of ..
- Anaesthesia techniques for dental patients with uncommon diseases. A series of case report
Abstract : Anaesthesia techniques for dental procedures are rarely debated among dentists and anaesthesiologists. Recommendations, indications and contraindications for sedation and/or general anaesthesia in dentistry are not so clearly established. Published scientific evidence are lacking and all the recommendations are therefo..
- First Cases of Uner Tan Syndrome in Anatolia, with Progressive Motor Improvement, Adaptive Self-Organization and Emergence of Late Childhood Quadrupedalism
Abstract : Background. Uner Tan Syndrome (UTS) was first described in 2005 and consists of three main symptoms: habitual locomotion on all four extremities, impaired intelligence with no conscious experience, an..
- Risk Factors Predicting Mortality in Spinal Cord Injury in Nigeria
Abstract : Objectives: Among spinal cord injured patients managed conservatively in Nigeria, to determine the number of death within the 6 month of injury and to identify risk factors that may be associated with such mortality. Design and setting: A retrospective cohort study set in Nigeria Methods: Patients were identified from ..
- Am I Losing My Marbles Doc?
My opinion: “Am I losing my marbles Doc?”Over the next few years this will be a question many doctors will hear from patients. And some of us will perhaps ask this of ourselves! As the leading edge of the ‘baby boomer’ generation moves through their 60’s and 70’s many of them will start to wonde..
- Screening Test for Metal Identification in Prosthetic Dentistry
Abstract : *The identification of the chemical nature of metallic restorations may provide useful information in odontological diagnosis. *Dentists commonly use the splint-test for such identification. Abrasion debris is collected from the metal restoration in the patient’s mouth, and the sample is then sent to a laboratory..
- Antimicrobial Constituents Of Conyza Floribunda
Abstract: The study describes the antibacterial and antifungal effects of both CH2Cl2 and MeOH crude extracts, collected fractions and pure isolates of Conzya floribunda. The antimicrobial activity tests were carried out using agar diffusion method. In vitro tests using CH2Cl2 and MeOH extracts of C. floribunda showed anti-bacte..
- Global Positioning System: Effective Tool in Protection of Women's Dignity
Abstract: Protection of women’s rights and dignity especially against increasing incidence of sexual assault has embodied as a prime national issue. The Supreme Court of India has had to redefine the term “sexual assault” in a measure to curb this social evil. Cries of increasing protests have resonated in legi..
- Postprostatectomy Urethral Stricture in Elderly Nigerians
Abstract: Purpose: We examined the outcome of urethral dilation in elderly patients of the Igbo ethnic group in Nigeria for stricture that supervened on radical prostatectomy. Methods: In this study, 10 men aged 65 years or older with proved urethral strictures underwent dilation. Their disease followed radical prostatectomy dur..
- Design Optimization and Evaluation of pH Responsive Prednisolone Sustained Release Tablet for Ileo-colonic Delivery
Abstract: The focus of this work is to provide accurate and effective treatment of inflammatory bowel disorders like ulcerative colitis. The necessity and advantages of colon-specific drug delivery systems have been well recognized and documented. Generally, the single approaches to obtain colon-specific delivery achieved limite..
- Molecular Interplay
My opinion: Molecules play important role at various levels in the life of organisms1. They are not only involved in the biological and physiological functions but also percolated in the field of behaviour and business2,3. The same has been highlighted in a poetic style to facilitate the students of Biology to know the scope of di..
- In Vitro Capacitation of Bull Spermatozoa: Role of Vitamin E
Abstract: The aim of this work was to study the influence of vitamin E (2mM) on capacitation and acrosome reaction of crossbred cattle bull spermatozoa. Fresh semen suspended in TALP medium (pH 7.4) was divided into four equal fractions. All fractions; control (containing TALP + spermatozoa) and the experimental [treated / untre..
- A Rare Case of Invasive Lobular Breast Cancer in a Male
Abstract : Male breast cancer is rare, comprising 1% of all breast cancers and 1% of all cancers in men. Unlike in women, in men invasive lobular breast cancer (ILC) is very uncommon, making up 1% of all male breast cancers and 0.01% of all cancers in men. In the past, the low incidence of lobular breast cancer in men was thought..
- Long-term Clinical and Functional Evaluation of the Single Layer Interrupted Sutured W-ileoanal Pouch
Abstract : We present the long-term results of a unique consecutive series of 101 single layer W ileoanal pouch reconstructions (63 male, 38 female; age range 10-76 years, median 36 yrs) over a ten year period in a tertiary referral centre.All procedures were carried out by the same consultant colorectal surgeon using an interrup..
- Outcome And Complications In Women Undergoing Cervical Cerclage In A Tertiary Hospital In Kenya
Abstract : Objective: To determine the immediate and late complications of women undergoing cervical cerclage, as well as their pregnancy outcomes.Methods: This was a retrospective study based on traceable patient records over a 9-year period (2000 to 2008) undertaken at the Kenyatta National Hospital, Kenya’s major referra..
- A Review on Fast Dissolving Tablets
Abstract : Recently, fast-dissolving drug delivery systems have started gaining popularity and acceptance as new drug delivery systems, because they are easy to administer and lead to better patient compliance. Usually, elderly people experience difficulty in swallowing the conventional dosage forms (tablets, capsules, solutions ..
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