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Dr. Morten Thomsen

Copenhagen University Hospital
Juliane Maries Vej 24, building 9201

Brief Biography:


1. 2009: Industrial Ph.D. in neuroscience from Copenhagen University and NeuroSearch A/S
2. 2006: M.Sc. in Human Biology from Copenhagen University
3. 2002: Exchange student for six months at University of Queensland, Australia.


Academic positions:


1. 2009: present Post doctorate fellow at Neurobiology Research Unit,CopenhagenUniversityHospital
2. 2006-2009: Research Scientist and Ph.D. student at NeuroSearch A/S.
3. 2005: Research assistant at the University of Queensland, Australia.
4. 2002: Laboratory assistant at Novozymes A/S.
5. 2000: Assistant teacher in mechanics at the Danish Technical University.

Awards and grants

1. 2011: “Young Scientists Award” for excellent poster presentation at the 2011 ECNP Workshop on Neuropsychopharmacology for Young Scientists in Europe.
2. 2010: Granted ~200,000 € from the Danish Ministry of Science, Technology and Innovation for a two-year project on nicotinic receptors in Alzheimer’s disease.
3. 2008: 1st prize in “ErhvervsPhD-foreningens formidlingspris” (a national competition for Ph.d. students, given for excellent conveyance of scientific work to the public) for an article on my research on nicotinic receptors.
4. 2008: Finalist in the Neurodag 2008 oral presentation competition at Copenhagen University.
5. 2005: Granted the Body and Mind Scholarship from the University of Copenhagen.
6. 2004: Granted ~13,500 € for a one-year scholarship from the Peter and Emma Thomsen Foundation.

1. 2011: ECNP 2011 Oral presentation
2. 2011: ECNP Workshop on Neuropsychopharmacology for Young Scientists in Europe – poster presentation
3. 2010, 2009, 2008, 2007, 2005: Society for Neuroscience conference – poster presentation
4. 2009: International Conference on Schizophrenia Research – poster presentation
5. 2007: European College of Neuropsychopharmacology conference
6. 2007: Linking Affect to Action: Critical Contributions of the Orbitofrontal Cortex conference – poster presentation


Research interests:

Nicotinic receptors, Ly6 proteins, Schizophrenia, Alzheimer's disease, 5-HT receptors


Any other information:


1. Thomsen MS, El-Sayed, Mikkelsen, JD. Differential Immediate and Sustained Memory Enhancing Effects of Alpha7 Nicotinic Receptor Agonists and Allosteric Modulators in Rats, PLoS ONE, in press.
2. Thomsen MS, Weyn A, Mikkelsen, JD. Hippocampal α7 nicotinic acetylcholine receptor levels in patients with schizophrenia, bipolar disorder, or major depressive disorder. Bipolar Disorders, in press.
3. Thomsen MS and Mikkelsen, JD. The α7 nicotinic acetylcholine receptor complex: one, two or multiple drug targets? Curr Drug Targets, in press.
4. Jensen MM, Lange SC, Thomsen MS, Hansen HH, Mikkelsen JD. The pharmacological effect of KCNQ (Kv7) positive modulators on dopamine release from striatal slices. Basic Clin Pharmacol, in press.
5. Thomsen MS, Hansen HH, Mikkelsen, JD (2010). Alpha 7 nicotinic receptor agonism mitigates phencyclidine-induced changes in synaptophysin and Arc gene expression in the mouse prefrontal cortex. Neurochem Int, 57:756-761.
6. Christensen DZ, Mikkelsen JD, Hansen HH, Thomsen MS (2010). Repeated administration of α7 nicotinic acetylcholine receptor (nAChR) agonists, but not positive allosteric modulators, increases α7 nAChR levels in the brain. J Neurochem, 114:1205-16 .
7. Thomsen MS, Hay-Schmidt A, Hansen HH, Mikkelsen JD (2010) Distinct neural pathways mediate alpha7 nicotinic acetylcholine receptor-dependent activation of the forebrain. Cereb Cortex, 20:2092-102.
8. Thomsen MS, Hansen HH, Timmermann DB, Mikkelsen JD (2010). Cognitive improvement by activation of α7 nicotinic acetylcholine receptors: From animal models to human pathophysiology. Curr Pharm Design, 16:323-343.
9. Thomsen MS, Hansen HH, Mikkelsen JD (2010) Opposite effect of phencyclidine on activity-regulated cytoskeleton-associated protein (Arc) in juvenile and adult limbic rat brain regions. Neurochem Int, 56:270-275.
10. Mikkelsen JD, Thomsen MS, Hansen H, Lichota J (2010). Use of biomarkers in discovery of novel anti-schizophrenia drugs. Drug Discov Today, 15:137-141.
11. Trajkovska V, Santini MA, Marcussen AB, Thomsen MS, Hansen HH, Mikkelsen JD, Arneberg L, Kokaia M, Knudsen GM, Aznar S (2009). BDNF downregulates 5-HT(2A) receptor protein levels in hippocampal cultures. Neurochem Int, 55:697-702.
12. Trajkovska V, Kirkegaard L, Krey G, Marcussen AB, Thomsen MS, Chourbaji S, Brandwein C, Ridder S, Halldin C, Gass P, Knudsen GM, Aznar S (2009). Activation of glucocorticoid receptors increases 5-HT(2A) receptor levels. Exp Neurol. 218:83-91.
13. Thomsen MS, Christensen DZ, Hansen HH, Redrobe J, Mikkelsen JD (2009) Alpha 7 nicotinic acetylcholine receptor activation prevents behavioral and molecular changes induced by repeated phencyclidine treatment. Neuropharmacology. 56:1001-1009.
14. Thomsen MS, Mikkelsen JD, Timmermann DB, Peters D, Hay-Schmidt A, Martens H, Hansen HH (2008) The selective alpha7 nicotinic acetylcholine receptor agonist A-582941 activates immediate early genes in limbic regions of the forebrain: Differential effects in the juvenile and adult rat. Neuroscience 154:741-753.
15. Soderman A, Thomsen MS, Hansen HH, Nielsen EO, Jensen MS, West MJ, Mikkelsen JD (2008) The nicotinic alpha(7) acetylcholine receptor agonist SSR180711 is unable to activate limbic neurons in mice overexpressing human amyloid-beta(1-42). Brain Res 1227:240-247.
16. Kristensen SE, Thomsen MS, Hansen HH, Timmermann DB, Hay-Schmidt A, Mikkelsen JD (2007) The alpha7 nicotinic receptor agonist SSR180711 increases activity regulated cytoskeleton protein (Arc) gene expression in the prefrontal cortex of the rat. Neurosci Lett 418:154-158.


What I think of the idea behind WebmedCentral:

I think it is a good attempt at speeding up the publication process, which is still one of the greater impediments to increasing the advancement of science.

As a note, I have just waited 9 months from the acceptance to the publication of a review article I made. So I appreciate any attempt to speed this process up


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