Brief Biography:
Dr. Devan Moodley is a medical biochemist by training. During his doctoral studies, he investigated abnormalities in rheumatoid peripheral lymphocytes using biochemical approaches. In particular, his studies showed for the first time that mitochondrial dysfunction in circulating lymphocytes played a role in severity of rheumatic disease. In addition, his studies showed that peripheral lymphocytes in rheumatoid arthritis initiate apoptosis whilst in circulation, but fail to fully execute the program and thus persist. This was shown to be dependent on cell stress responses mediated by heat shock protein 70.
Currently he investigates the role of non-coding RNA in the development on immunological tolerance.
Academic positions:
Lecturer in Medical Biochemistry - University of KwaZulu-Natal, Durban, South Africa
Research Fellow - Department of Microbiology and Immunobiology, Harvard Medical School, Boston, USA
Research interests:
Non-coding RNA and transcriptional regulation
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