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Dr. Archana Varadaraj

Postdoctoral Fellow
European Oncology Institute
IFOM-IEO Campus, Via Adamello 16

Brief Biography:

Education and current position

1. May ’14-current: Postdoctoral Fellow at the Department of Drug Discovery and Biomedical  Sciences, University of South Carolina
2. April ’10-March ‘14: Postdoctoral Fellow at The European Oncology Institute (FUV
independent postdoctoral fellowship 2014)
3. May ’07-February ’09: Postdoctoral training at The Ohio State University
4. October ‘02-August ’06: Christ’s College, University of Cambridge

Graduation July, 2007; Research leading to a P.hD in Pathology


Academic positions:

Research experience

1. September 17 ’04: Training course on “Concepts and methods of Programmed Cell Death”- Chania, Greece
Course involving lectures and discussions on different apoptotic modes of cell death
including current approaches in studying them. (Marie Curie Travel award)
2. January ’02: Centre    for Biotechnology- Anna University, India. Laboratory research for
final year study on techniques in Molecular Biology
3. May-July ’01: Summer visiting student-fellow of the Indian Academy of Sciences- India.
Worked on the antioxidant role of Lansoprazole and its anti-ulcer effect gaining training in animal handling, free radical generation, DNA analysis and interpretation of the chemical modification of the drug Lansoprazole- see publication section.

Awards and Scholarships received

1. December ’13: Awarded the FUV Cancer Fellowship to carry out an independent research project on Human Papillomavirus and protein Ubc9 regulation
2. August ’02: Awarded a full cost Cambridge Nehru Scholarship to pursue a research degree in Pathology, University of Cambridge.
3. May ’02: Selected by the Government of India to form part of a 20 member team of
students/young researchers to attend the Meeting of Nobel Laureates and Students in Lindau, Germany
4. December ’01: Qualified the CSIR-UGC National Entrance Test conducted in India selecting the top 1% candidates eligible to pursue a research degree in any Indian national laboratory.
5. December ’01: Qualified as being eligible for a lectureship post by the Union Grants
Commission (UGC) - a government funding body.
6. May-July ’01: Selected by the Indian Academy of Sciences as Student-Fellow to work on a research project at Indian Institute of Chemical Biology, Kolkata, India.
7. August ’97-’00: Union General Proficiency Medal for securing the highest mark in B.Sc.
8. August ’97-’00: Awarded a Merit Scholarship consequently for three years.
9. April ’00: Obtained State First rank in English
10. April ’00: Recipient of Endowment Prize for securing the highest mark in English


Research interests:

Cellular Biology, Molecular Biology


Any other information:


1. Maria Pozzebon*, Archana Varadaraj*, Domenico Mattoscio et al. (2013) A BC-box
domain-related mechanism for VHL protein degradation. Proc Natl Acad Sci 110(45): 18168-18173  (*joint first authors)
2. Liu HL, Osmani AH, Ukil L, Son S, Markossian S, Shen KF, Govindaraghavan M, Varadaraj A, Hashmi SB, De Souza CP, Osmani SA (2010) Single-step affinity purification for fungal proteomics. Eukaryot Cell 9(5): 831-833
3. Ukil L, Varadaraj A, Govindaraghavan M, Liu HL, Osmani SA (2008) Copy number suppressors of the Aspergillus nidulans nimA1 mitotic kinase display distinctive and highly dynamic cell cycle-regulated locations. Eukaryot Cell 7(12): 2087-2099
4. Varadaraj A, Dovey CL, Laredj L, Ferguson B, Alexander CE, Lubben N, Wyllie AH, Rich T
(2007) Evidence for the receipt of DNA damage stimuli by PML nuclear domains. J Pathol
211(4): 471-480
5. Rich T, Varadaraj A (2007) Ataxin-1 fusion partners alter polyQ lethality and aggregation. PLoS One 2(10): e1014
6. Dovey CL*, Varadaraj A*, Wyllie AH, Rich T (2004) Stress responses of PML nuclear domains are ablated by ataxin-1 and other nucleoprotein inclusions. J Pathol 203(4): 877-883 (*joint first authors)
7. Biswas K, Bandyopadhyay U, Chattopadhyay I, Varadaraj A, Ali E, Banerjee RK (2003) A novel antioxidant and antiapoptotic role of omeprazole to block gastric ulcer through scavenging of hydroxyl radical. J Biol Chem 278(13): 10993-11001


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