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Dr. Soumendrakrishna Karmahapatra

GU,Oncology. OSU, Pharmacology

Brief Biography:


1. University of Calcutta - India
Doctor of Philosophy Degree (Ph.D)

2. Vidyasagar University - India
Master of Science Degree (M.Sc)



Academic positions:

Positions/Research Experience

1. Scientist TheOhio State University, ColumbusOH    
2. Postdoctoral Fellow Georgetown University, Washington DC
3. Doctoral Fellow National Medical College, Calcutta,India September, 2003-August, 2009.


1. Research investigator in Philip Morris USA Inc, sponsored project "Insulin induced nitric oxide synthesis in platelets in habitual cigarette smokers".


Research interests:

Pharmacology, Oncology


Any other information:


1. Soumendra K Karmahapatra, Saha T, Adhikari S, Woodrick J, Roy R. Redox regulation of purinic/apyrimidinic endonuclease 1 activity in Long-Evans Cinnamon rats during spontaneous hepatitis.Mol Cell Biochem. 2014 Mar;388(1-2):185-93.
2. Adhikari S,Soumendra K Karmahapatra, Karve TM, Bandyopadhyay S, Woodrick J, Manthena PV, Glasgow E, Byers S, Saha T, Uren A. Characterization of magnesium requirement of human 5'-tyrosyl DNA phosphodiesterase mediated reaction.BMC Res Notes. 2012 Mar 9;5:134.
3. Adhikari S, Manthena PV, Kota KK, Soumendra K Karmahapatra, Roy G, Saxena R, Uren A, Roy R. A comparative study of recombinant mouse and human apurinic/apyrimidinic endonuclease.Mol Cell Biochem. 2012 Mar;362(1-2):195-201.
4. Adhikari S,Soumendra K Karmahapatra, Elias H, Dhopeshwarkar P, Williams RS, Byers S, Uren A, Roy R. Development of a novel assay for human tyrosyl DNA phosphodiesterase 2. Anal Biochem. 2011 Sep 1;416(1):112-6.
5. Ghosh R, Soumendra K Karmahapatra, Bhattacharyya M, Bhattacharya R, Bhattacharya G, Sinha AK. The appearance of dermcidin isoform 2, a novel platelet aggregating agent in the circulation in acute myocardial infarction that inhibits insulin synthesis and the restoration by acetyl salicylic acid of its effects.J Thromb Thrombolysis. 2011 Jan; 31(1):13-21.
6. Ghosh R, Soumendra K Karmahapatra, Bhattacharya G, Kumar Sinha A. The glucose-induced synthesis of insulin in liver.Endocrine. 2010 Oct;38(2):294-302. Epub 2010 Oct 23.
7. Soumendra K Karmohapatra., Nighat N Kahn., Asru K Sinha. The thrombolytic effect of aspirin in animal model. J Thromb Thrombolysis.  2007 Oct; 24(2):123-9.
8. Soumendra K Karmohapatra., KushalChakraborty.,Nighat N Kahn., and Asru K Sinha. The role of nitric oxide in the aspirin induced thrombolysis in vitro and the purification of aspirin activated nitric oxide synthase from human blood platelets. Am J Hematol. 2007; 82 (11) :986-995.
9. Soumendra K Karmohapatra., Kushal Chakraborty. Nighat N Kahn., Asru K Sinha. Aspirin induced thrombolysis in the presence of platelets. Ind. J. Physiol. Allied Sci. 2007; 60 (4): 58-71.
10. Mau Bhattacharyya., Girish G.V., Soumendra K. Karmohapatra., Samad S.A. and Asru.K.Sinha. Systemic Production of IFN-alpha by Garlic (Allium sativum) in Humans. J Interferon Cytokine Res. 2007 May; 27(5):377-82.
11. Bhattacharyya M, Soumendra K Karmahapatra, Bhattacharya G, Bhattacharya R, Sinha AK. The role of leucocytes in the acetyl salicylic acid (aspirin) induced nitric oxide synthesis in the production of interferon-alpha, a potent inhibitor of platelet aggregation and a thrombolytic agent.J Thromb Thrombolysis. 2009 Aug; 28(2):173-84.
12. Somashree Chakraborty, Gausal A. Khan, Soumendra K. Karmohapatra, Rabindra      Bhattacharya, Gorachand Bhattacharya, and A. Kumar Sinha, Purification and mechanism of action of ‘‘cortexin,’’ a novel antihypertensive protein hormone from kidney and its role in essential hypertension in men. J Am SocHypertens. 2009 3(2):119-32.
13. Kushal Chakraborty, Nehi Sinha, Girish GV, Soumendra K Karmohapatra, Gausal A Khan, Asru K Sinha. Control of hyperglycemia by nitric oxide generating foods in diabetes mellitus. Ind. J. Physiol. Allied Sci. 2007; 60 (1): 89-102.
14. Girish GV, Soumendra K Karmahapatra, Kushal Chakraborty, Udayan Ray, Nighat N Kahn, Mau Bhattacharyya, Asru.K.Sinha. Appearance of an aberrant form of α-antitrypsin in the circulation of chronic cigarette smokers and its effect on the insulin induced NO synthesis in blood platelets. (Communicated).
15. Sinha Nehi., Chakraborty Kushal., Soumendra K Karmahapatra., Kahn Nighat., G.V. Girish., Sinha Asru. Purification of nitric oxide generating protein from garlic (Allium Sativum) and its effect on Ehrlich’ Ascitic Cells induced malignancy in mice. (Communicated).
16. "Allimin." Chakraborty K., Girish G.V., Soumendra K Karmahapatra.,Kahn N.N., Sinha K.A. Submitted (APR-2004) to UniProtKB. PROTEIN SEQUENCE OF 31-65.


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