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This is an excellent question to "attempt" to answer. Some report that serum steady state blood levels CoQ10 do not correlate with the availability of either Ubiquinone or Ubiquinol for conversion to ATP in exercising muscles.
Coenzyme Q10 is not a banned substance according to the International Olympic Committee or the sub-committee for the USA Olympic organization. Coenzyme Q10 may be tested in blood serum levels. Some state that if it is deficient in working muscles, it may be tested by a series of urine tests.
I quote:
"In patients with mitochondrial dysfunction due to CoQ10 need, not only will the markers for CoQ10 (succinate, fumarate, malate, and hydroxymethylglutarate) elevate, but all of the compounds in the Krebs Cycle will elevate because electrons generated in the Krebs Cycle cannot continue into the electron transport chain to make ATP." [from Why Test for Coenzyme Q10? by Cass Nelson-Dooley, MS, Richard Lord, PhD, and J. Alexander Bralley, PhD @ http://www.metametrixinstitute.org/content/articles/WhyTestforCoenzymeQ10.pdf]
Bill Misner PhD
- competing interests: None.
- Invited by the author to make a review on this article? :
- Experience and credentials in the specific area of science:
Author of this Case Report.
- Publications in the same or a related area of science: Yes
- References: None
Dear Esteemed Reviewers,
To perform a review on the original manuscript, please clidk the pdf. version without reviews.
The manuscript posted with the reviewers reviews is NOT the original manuscript; it has several errors that occurred outside the author's control after the original manuscript was submitted.Please therefore perform your review on the Original Manuscript here:
"Coenzyme Q-10 Effects Endurance Running Performance - A Case Report"
http://www.webmedcentral.com/wmcpdf/Article_WMC002400.pdf
Bill Misner PhD
- competing interests: None.
- Invited by the author to make a review on this article? :
- Experience and credentials in the specific area of science:
Author of this Case Report.
- Publications in the same or a related area of science: No
- References: None
Dear Esteemed Reviewers,
To perform a review on the original manuscript, please clidk the pdf. version without reviews.
The manuscript posted with the reviewers reviews is NOT the original manuscript; it has several errors that occurred outside the author's control after the original manuscript was submitted.Please therefore perform your review on the Original Manuscript here:
"Coenzyme Q-10 Effects Endurance Running Performance - A Case Report"
http://www.webmedcentral.com/wmcpdf/Article_WMC002400.pdf
Bill Misner PhD
- competing interests: None.
- Invited by the author to make a review on this article? :
- Experience and credentials in the specific area of science:
Author of this Case Report.
- Publications in the same or a related area of science: No
- References: None
The author himself is the subject of the study so some bias may occur; however in tis case study during running it does not seem to have occurred.
Second run is better than first; to rule out effect of extra month of training, experiment may be repeated with change of drug-month-order.
Does this drug come under banned list for athlets ? Is the drug residue testable in urine sample ?
Studying Q-10 as anti-oxidant.