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Submited on: 28 Nov 2011 02:37:11 PM GMT
Published on: 29 Nov 2011 04:52:30 PM GMT
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Other Comments:
This is an excellent summary and analysis of the role of host genetics in evolution and disease. The review is insightful, thorough and well written.
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Competing interests:
None
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Invited by the author to review this article? :
Yes -
Have you previously published on this or a similar topic?:
No
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References:
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Experience and credentials in the specific area of science:
I am interested in the role of host genetics in the genetic diversity and evolution of HIV and have recently initiated research in this field.
- How to cite: Hewlett I .Lessons from Immunogenetics Unfold Inherent Demographic Health Issues[Review of the article 'Lessons from Immunogenetics Unfold Inherent Demographic Health Issues ' by Sreerama K].WebmedCentral 2014;3(1):WMCRW001332
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Other Comments: Congratulations, it's an excellent review on the subject.
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Competing interests:
No
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Invited by the author to review this article? :
No -
Have you previously published on this or a similar topic?:
Yes
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References:
1. Guadalupe Garcia-Elorriaga, Guadalupe Carrillo-Montes, Melby Mendoza-Aguilar and Cesar Gonzalez-Bonilla. Polymorphisms in Tumor Necrosis Factor and lymphotoxin a in Tuberculosis and Without Response to Treatment with. Inflammation. 2010, 33 (4) :267-275. 2. Tumor necrosis factor (TNF) -308 and lymphotoxin (LTA) +252 polymorphisms in Kawasaki disease Children with coronary aneurysms and in Mexico. Francisco Cruz-Olivo, Guadalupe Garcia-Elorriaga, Cesar Gonzalez-Bonilla, Guillermo del Rey-Pineda, and Javier Mancilla-Ramirez. In press, Arch Med Res. -
Experience and credentials in the specific area of science:
I worked on the subject of SNP's for 6 years. TNF and IL-10 SNP's. - How to cite: Garcia G .Lessons from Immunogenetics Unfold Inherent Demographic health Issues.[Review of the article 'Lessons from Immunogenetics Unfold Inherent Demographic Health Issues ' by Sreerama K].WebmedCentral 2014;2(11):WMCRW001176
The main purpose of this paper is to demonstrate that the genotyping of immune-related genes and the recording of their frequencies in the local populations provide clues to upkeep their role in the survival advantage of homo sapiens.
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Yes- it would be a great lecture at a medical school.
The authors state that variation among individuals of human population lies at different levels. We are endowed with the potential for innate and adaptive immunity due to evolution. The evolutionary selection pressure invested humans with a variety of immune-related genes.
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clinical associate professor