Submited on: 22 Mar 2011 11:44:28 AM GMT
Published on: 23 Mar 2011 08:42:11 PM GMT
 

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Partly
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? No
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? No
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    ligne 15 : the presence of a 56*37 mm mass extending..

    ligne 24 : preoperative chemotherapy rather than neoadjuvant chemotherapy

    ligne 33: Synovial sarcomas often arises

    ligne 41: O'keefee et al in 1993 (3

    ligne 43:  Mackenzie et al  suggested .. reference ??

     

    Concerning imaging: is MRI better ??

  • Competing interests:
    no
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    experience in diagnosis and treatment of sarcoma.

     

    Some articles published in other area.

  • How to cite:  Kaikani W .Primary Synovial Sarcoma of the Inner Ear: A Case Report[Review of the article 'Primary Synovial Sarcoma of the Inner Ear: A Case Report ' by Errihani H].WebmedCentral 2011;2(6):WMCRW00835
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Synovial sarcoma ORL
Posted by Dr. Youssef Bensouda on 18 May 2011 01:03:22 PM GMT

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? No
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    Nice and original artcile,

    I join the comments made by the other authors

  • Competing interests:
    no
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    Oncology

  • How to cite:  Bensouda Y .Synovial sarcoma ORL[Review of the article 'Primary Synovial Sarcoma of the Inner Ear: A Case Report ' by Errihani H].WebmedCentral 2011;2(5):WMCRW00769
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  • Other Comments:

    I think this is a very interesting article. It shows us a very rare clinical case of a primary synovial sarcoma arising of the inner ear. The communication of these kind of rare clinical cases is understandable from the point of view of increasing the doctors´ awareness about the relevance of expedite diagnosis and treatment and also to increase the knowledge of these diseases to make doctors suspect about their existence. Despite of the comments above, I think this article could be somewhat improved. Sometimes it needs a language polishment.

    In the introduction the authors should include more data about the synovial sarcomas in general, frequency, most usual locations and therapeutic approaches. Then, authors could focus (as they have done) on the ear tumours and the relevance of early diagnosis and treatment to get the best results.

    In the section “Case report”, authors should explain the abbreviation they have used FNCLCC (French Federation of Cancer Centers Sarcoma Group).

    I would like to have seen if this case was treated in a multidisciplinary committee and if radiation therapy was considered as neoadjuvant treatment as chemotherapy was.

    I miss some pictures about histology.

    I would like also to know why this patient had received oral cyclophosphamide as palliative treatment once she had got progressive disease with the combination of ifosfamide and doxorubicin and for how long was she receiving this treatment and also the evolution she presented (stable disease, partial remission or progressive disease). On the other hand the dosis of palliative radiotherapy and the clinical benefits she got from this technique.

    I think all these points would improve our knowledge about this rare disease.

    In the end the references need to be reviewed (there is a mistake in reference 3).

    Esther Una Cidon, MD, PhD, Professor

  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:
    None
  • How to cite:  Una Cidon E .A very rare clinical entity: Sarcoma of the year[Review of the article 'Primary Synovial Sarcoma of the Inner Ear: A Case Report ' by Errihani H].WebmedCentral 2011;2(4):WMCRW00664
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? No
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? Yes
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    Thank you for this interesting case report.

     

    I was only able to see the CT image before treatment, not afterwards. Also, do you have an MRI? Do you have a PET/CT image? In your description of the CT, please give units of measurement.

     

    Some of the abbreviations you used were unfamiliar to me. Could you please give the full description instead of just abbreviations?

  • Competing interests:
    no
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    Molecular imaging physician.

  • How to cite:  Heston T F.Review of a Case Report on Primary Synovial Sarcoma of the Inner Ear[Review of the article 'Primary Synovial Sarcoma of the Inner Ear: A Case Report ' by Errihani H].WebmedCentral 2011;2(4):WMCRW00661
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? Yes
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    I suggest to:

    refere to the grading system that was used

    add the illustrations for the IHC for EMA, PSA100, CD34, HMB45, KL1, and desmine with the proper positive and negative controls

    add the scoring system for these markers and illustrate why they have been used (e.g. desmine as myoepithelial marker, KL1 as epithelial marker .....etc)

    Explain why diagnosis was not confirmed by molecular markers

    Follow consistent method in writing refereces

     

     

  • Competing interests:
    No
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    Yes
  • References:
    None
  • Experience and credentials in the specific area of science:

    oncology

  • How to cite:  El-Abd E I.Primary Synovial Sarcoma of the Inner Ear: A Case Report [Review of the article 'Primary Synovial Sarcoma of the Inner Ear: A Case Report ' by Errihani H].WebmedCentral 2011;2(3):WMCRW00629
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Primary Synovial sarcoma of the inner ear?!
Posted by Dr. Narendra Hulikal on 26 Mar 2011 05:57:08 AM GMT

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Partly
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? No
5 Are structure and length satisfactory? No
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? Yes
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? No
10 Are the references adequate and are they all necessary? No
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    I wish authors should elaborate on certain issues and also calrify few of them. Can they clarify the exact site of origin of the tumor as it appears clinically as well as on CT films to be involving external and middle ear, mastoid  and temperomandibular area and not inner ear. There are case reports of the tumor arising from temperomandibular region (atleast 2). Authors should have provided illustration of microscopic findings. It is difficult to diagnose these tumors in small specimens even by experienced sarcoma pathologist. At present time diagnosis of monphasic synovial sarcoma needs demonstration of X;18 translocation which is characteristic of these tumors. Extensive articles on synovial sarcoma of head and neck and orbit can be found.

  • Competing interests:
    none
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    surgical oncologist in an academic institute

  • How to cite:  Hulikal N .Primary Synovial sarcoma of the inner ear?![Review of the article 'Primary Synovial Sarcoma of the Inner Ear: A Case Report ' by Errihani H].WebmedCentral 2011;2(3):WMCRW00627
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Partly
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? Yes
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    This manuscript reports a rare case of a primary case of synovial sarcoma localized in the middle ear.

    The manuscript may need the addition of the histological analysis.

    Minor corrections are also needed (e.g. consistency in the references).

  • Competing interests:
    None
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    Cancer.

  • How to cite:  Yakisich J S.Primary Synovial Sarcoma of the Inner Ear: A Case Report [Review of the article 'Primary Synovial Sarcoma of the Inner Ear: A Case Report ' by Errihani H].WebmedCentral 2011;2(3):WMCRW00622
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