My opinion
 

By Dr. Deepak Gupta , Dr. Sarwan Kumar , Dr. Berhane Seyoum
Corresponding Author Dr. Deepak Gupta
Wayne State University, - United States of America
Submitting Author Dr. Deepak Gupta
Other Authors Dr. Sarwan Kumar
Wayne State University, Internal Medicine, - United States of America

Dr. Berhane Seyoum
Wayne State University, Internal Medicine, - United States of America

ENDOCRINOLOGY

Growth Hormone, Evolution, Nutrition, Sanitation, Medication

Gupta D, Kumar S, Seyoum B. Does Growth Hormone Need the Growth? Maybe Not Anymore. WebmedCentral ENDOCRINOLOGY 2022;13(2):WMC005770

This is an open-access article distributed under the terms of the Creative Commons Attribution License(CC-BY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
No
Submitted on: 21 Feb 2022 01:03:04 AM GMT
Published on: 22 Feb 2022 04:26:37 AM GMT

My opinion


We have always tried to be the seekers of the facts. But as the facts keep evolving with our constantly evolving understandings, the facts seem to lose the battle to the truths. The truths seem to give an uncanny stability to the minds whose beliefs in their truths become the absolutes, immune to the wavered evolution of facts. The bottom line is that when finish line keeps moving and new normal keeps evolving every other moment, accepting and embracing the ever-changing facts become tardy and tedious to the minds thus converting their pursuit of faltering facts into their sticking to unshakeable truths.

 

Henceforth, we will just raise our questions and leave it up to the readers to ponder and wonder what the facts are and what the truths can be.

 

  • What is the normal growth of human body? What is the normal life span of human body? What is the normal purpose of human body?
  • Do the definitions, parameters and classifications about what’s considered normal in terms of growth or life span or purpose change with changing times inducing adaptations in human bodies surviving the changing environments?
  • Why did humans evolve to have certain heights and weights during their evolutionary histories where their ancestors had to adapt to their hunting-and-gathering environments thus making certain heights and weights as the new normal for their descendants [1-2]?
  • How did improved human nutrition with abundant food production in the agricultural societies allowed certain heights and weights becoming more prominent among the well-fed humans [3]?
  • Did the human sanitation worsen in the agricultural societies before improving eventually in the urban societies leading to additions of more inches and more pounds to toilet-trained humans’ new normal heights and weights [4-5]?
  • How did the modern human salesmanship allow the eradication of biomes [6] within and without before adding the actual growth hormones to the marketable milieu of modern pill-popping humans who are always looking forward to normalize their never-normal perceived heights and weights [7-9]?

 

As far as for us, the bottom line is that just like everything else in the matrix, the sole purpose of human body is to just exist wherein just like every other self-perpetuating entity in the matrix, the sole purpose of life span for human body is to allow sufficient time for creating self-perpetuating copies of the body to last long after the original body has “gone with the wind” and just like every other growing entity in the matrix, the sole purpose of growth in human body is to mature the body’s ability to self-perpetuate. Everything else is just a charade to make sense out of nonsensical matrix that keeps evolving with each passing moment and still remains nonsensical always because it will always remain impossible to identify, quantify and classify the growth whether it is the growth in the quantity of lives or quality within the lives or whether it is the growth of humanity over other species or technology over humanity itself.

Reference(s)


  1. Short stature in rainforest hunter-gatherers potentially linked to cardiac adaptations. https://www.sciencedaily.com/r eleases/2018/11/181112131543.htm
  2. In northern humans, evolution favored shorter bones - but with a painful trade-off. https://med.stanford.edu/news/all-news/2017/07/decreasing-height-increasing-arthri tis-risk-evolutionarily.html
  3. MC3R links nutritional state to childhood growth and the timing of puberty. https://www.nature.com/articles/s41586-021 -04088-9
  4. Beyond Malnutrition: The Role of Sanitation in Stunted Growth. https://ehp.niehs.nih.gov/doi/10.1289/ehp. 122-A298
  5. Association of Poor Sanitation With Growth Measurements Among Children in India. https://jamanetwork.com/ journals/jamanetworkopen/fullarticle/2764400
  6. The Ecology of Height: The Effect of Microbial Transmission on Human Height. https://muse.jhu.edu/article/26156
  7. Most Loved China Drug Stock Sells Hormones to Make Kids Taller. https://www.bnnbloomberg.ca/most-loved-china-drug-stock-sells-hormones-to-make-kids-taller-1 .1251133
  8. Global Human Growth Hormone Market Is Expected to Reach USD 10.83 billion by 2028 : Fior Markets. https://www.globenewswi re.com/en/news-release/2021/02/11/2174437/0/en/Global-Human-Growth-Hormone-Market-Is-Expected-to-Rea ch-USD-10-83-billion-by-2028-Fior-Markets.html
  9. The Use and Abuse of Human Growth Hormone in Sports. https://journals.sagepub.com/doi/10 .1177/1941738118782688

Source(s) of Funding


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Competing Interests


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