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- In Vitro Capacitation of Bull Spermatozoa: Role of Vitamin E
Abstract: The aim of this work was to study the influence of vitamin E (2mM) on capacitation and acrosome reaction of crossbred cattle bull spermatozoa. Fresh semen suspended in TALP medium (pH 7.4) was divided into four equal fractions. All fractions; control (containing TALP + spermatozoa) and the experimental [treated / untre..
- A Rare Case of Invasive Lobular Breast Cancer in a Male
Abstract : Male breast cancer is rare, comprising 1% of all breast cancers and 1% of all cancers in men. Unlike in women, in men invasive lobular breast cancer (ILC) is very uncommon, making up 1% of all male breast cancers and 0.01% of all cancers in men. In the past, the low incidence of lobular breast cancer in men was thought..
- Long-term Clinical and Functional Evaluation of the Single Layer Interrupted Sutured W-ileoanal Pouch
Abstract : We present the long-term results of a unique consecutive series of 101 single layer W ileoanal pouch reconstructions (63 male, 38 female; age range 10-76 years, median 36 yrs) over a ten year period in a tertiary referral centre.All procedures were carried out by the same consultant colorectal surgeon using an interrup..
- Outcome And Complications In Women Undergoing Cervical Cerclage In A Tertiary Hospital In Kenya
Abstract : Objective: To determine the immediate and late complications of women undergoing cervical cerclage, as well as their pregnancy outcomes.Methods: This was a retrospective study based on traceable patient records over a 9-year period (2000 to 2008) undertaken at the Kenyatta National Hospital, Kenya’s major referral an..
- A Review on Fast Dissolving Tablets
Abstract : Recently, fast-dissolving drug delivery systems have started gaining popularity and acceptance as new drug delivery systems, because they are easy to administer and lead to better patient compliance. Usually, elderly people experience difficulty in swallowing the conventional dosage forms (tablets, capsules, solutions ..
- Non-Invasive Rodent Cardiac Output: Comparison of a Compact Clinical Monitor with Echocardiography
Abstract : Background: There are limited options for non-invasive cardiac output (CO) measurement in rodents. This study aimed to compare a commercially available human CO monitor, USCOM® (USCOM Ltd, Sydney, Australia), with specialised rodent echocardiography for rat CO measurement.Methods: With institutional ethics committee a..
- Shoe-smell Application as a First-aid Interventional Measure in Controlling Epileptic Attacks in an Urban Population in India: A Fortuitous Empirical Finding
Abstract: Diseases possessing long history of existence have been associated with various kinds of interventional (pharmacological and non-pharmacological) measures adopted by the patients or their caretakers in attempt to abort or attenuate the severity/intensity of the disease. One such disease is epilepsy, which has been know..
- Gastrointestinal involvement revealing Henoch Schonlein Purpura in Adults: Report of Three Cases and Review of the Litterature
Abstract : The diagnosis of Henoch-Schonlein purpura (HSP) is difficult, especially when abdominal symptoms precede cutaneous lesions. We report three cases of adult HSP revealed by gastrointestinal (GI) involvement...
- Bladder Stones in Catheterized Spinal Cord Injured Patients in Nigeria
Abstract : Objective: To determine the incidence of bladder stone in patients with spinal cord injury (SCI) and to assess if catheter encrustation and positive urinary culture of Proteus mirabilis is predictive of bladder stone. Background: Bladder stones are common urological complication in those with spinal cord injury (SCI) ..
- Prevalence of Gastrointestinal Parasite in Goats in Shillong, Meghalaya, India
Abstract: A study was conducted regarding the level of burden of gastrointestinal Parasites in goat slaughtered for human consumption in Shillong, Meghalaya during June,2001 to June,2006. A total of 250 gastrointestinal tract were examined for adult parasites. The intensity of parasitic infection was recorded maximum in rainy se..
- Incidence of Trans Rectal Ultra Sound Guided Prostatic Biopsy Related Mortality
Abstract : TRUS prostatic biopsy related mortality has been reported to be 1.3%. We felt that this was too high and did not reflect our experience. The objective of this study was to look at the TRUS related mortality in our centre. Material and Methods: Electronic search was carried out on all the patients who had TRUS prostatic..
- An updated checklist of helminth and protozoan parasites of birds in New Zealand
Abstract : A combined and updated checklist of helminth and protozoan parasites of birds in New Zealand is provided. This checklist, which is divided into two parts, includes a total of 203 parasites (68 nematodes, 40 cestodes, 44 trematodes, 11 acanthocephalans and 40 protozoans) from 116 hosts...
- Immuno-prophylaxis against development of cardiac valvular complications in patients with rheumatic fever: A proposed method
Abstract : Rheumatic heart disease (RHD) is a serious medical condition recognized as an immunologically mediated complication of rheumatic fever with an autoimmune component due to molecular mimicry between the bacterial antigens and certain body tissues. In view of the prevalence and seriousness of the disorder, its prophylaxis..
- Computer Assisted Design and in- Silica Metabolic Exploration of a Hemoglobin Docking Molecule- Early Steps of a Novel Antiplasmodial Agent
Abstract : This report presents the early steps in the development of a novel antimalarial agent. Using bio-informatics, human hemoglobin was targeted for docking a ligand at pre-specified regions of its three ..
- Bilateral Naso-sinusal Glandular Hamartoma: A Case Report
Abstract : Differential diagnosis of unilateral nasal mass may be a troublesome question, and also unusual conditions such as glandular hamartoma, consisting in non-neoplastic or inborn malformation, must be con..
- Evaluation of neural network performance in the protein secondary structure prediction problem
Abstract: In the context of the protein secondary structure prediction problem, we examine the performance of various neural network architectures commonly applied in the literature. Specifically,by applying the neural network paradigm, mappings between training vectors and their desired targets are constructed. The class member..
- Health Inequities and Investing in the Early Life Years: Lessons to reach to Poor and Vulnerable in Nepal
Abstract : It has clearly been proven in various studies that the poor suffer more than the rich in the matters of mortality, fertility, malnutrition, and morbidity, but it is the size of the gap between the rich and poor, which has caught the attention of policy makers and development agencies. Every year more than half a millio..
- Os Radiostyloideum- Misdiagnosed as fracture in the Emergency Room
Abstract : The author reports a case of Os radiostyloideum, misdiagnosed as fracture of the radial styloid, and subsequently managed with a back slab, in the emergency room...
- A Possible Mechanism of Abrogating Progression of Web Beyond Anti-Idiotypic Antibody and a Non Traditional Pathway of Complement Activation
Abstract: The progression of immune response is currently believed to give rise to anti-anti-idiotypic antibodies. This new hypothesis offers an explanation for the termination or abrogation of potentially endl..
- Medical Mythology: Its Etiology, Prevention and Treatment
Abstract : Myths are widely held beliefs that are false or of unverifiable existence. In medicine, they are not just unproven theories or mistaken conclusions, rather, they are fictitious ideas that weave their way throughout the profession. In order to prevent and treat medical myths, they need to be recognized as a disease that..
- Dendrimer: A Polymer of 21st Century
Introduction: A dendrimer is generally described as a macromolecule, which is characterized by its highly branched 3D structure that provides a high degree of surface functionality and versatility. Dendrimers have often been refered to as the “Polymers of the 21st century”. The unique architectural design of dendrimers, high deg..
- lbsen's Discovery of the Benefits of Positive Pressure Ventilation and Tom Petty's Discovery of PEEP
Review: The purpose of this review is to look at the evolution of artificial ventilation and examine the factors that led to the development of positive pressure ventilator systems used today.I. The Beginning of Artificial Ventilation: The idea of filling a person’s lungs with air for resuscitation purposes dates back to ant..
- Differential effects of estradiol and tamoxifen on pyrrolidon carboxypeptidase activity in the human estrogen-dependent and estrogen-independent breast cancer cell lines MCF-7 and EVSA-T
Abstract: Pyrrolidon carboxypeptidase (Pcp) (E.C 3.4.19.3) is an omega peptidase widely distributed in animal fluids and tissues, which hydrolyzes N-terminal pyroglutamic residues from biologically active peptides such as gonadotropin releasing hormone (GnRH). Previous results obtained in our laboratory showed a decrease of Pcp ..
- Human serum angiotensinase and vasopressin-degrading activities from childhood to elderly
Abstract: The increase of blood pressure with development and ageing has been extensively reported. The aim of this study is to analyse the changes in the angiotensinase and vasopressin-degrading activities in men and women in various age groups. Aminopeptidase N (APN), aminopeptidase B (APB) and vasopressin-degrading activity (..
- Toxicity of indole-3-acetic acid combined with horseradish peroxidase on Staphylococcus aureus
Abstract: We investigated the action of indole-3-acetic acid (IAA) combined with horseradish peroxidase (HRP) on Staphylococcus aureus death. S. aureus is a pathogen microorganism capable of causing several diseases. S. aureus was incubated for 1.5, 3.0, and 6.0 h in the absence (control) and presence of IAA, HRP or both IAA/HRP..
- Segmentation And Characterization Of Masses In The Digital Mammograms
Abstract: Breast tumor segmentation is needed for monitoring and quantifying breast cancer. However, automated tumor segmentation in mammograms poses many challenges with regard to characteristics of an image. A comparison of two different semi-automated methods, viz., modified gradient magnitude region growing technique (MGMRGT..
- Hypothesis-driven Research on Genomic Data Derived from a Large Scale Lung EQTL Mapping Study
Abstract: The introduction of Genome Wide Association Studies (GWAS) has allowed the identification of reproducible disease-associated loci for more than 100 complex disorders and biological traits. Although these discoveries show the power of a hypothesis-free, unbiased approach to gene association studies, the downstream effec..
- Endoscopic Detection and Removal of Recto-sigmoid Myomatous (Leiomyoma) Tumour
Introduction: Colonic Myomatous tumours; (Leiomyosarcoma and Leiomyoma) are a rare conditions. Only 3% of these smooth muscle tumours arising from colon are gastrointestinal leiomyomas and constitute about 0.1% of rectal tumours (1, 2). Most of these tumours are incidentally diagnosed on routine large bowel endoscopic examination (1..
- Mood Induction and Unintentional Learning in Healthy Subjects
Abstract: Whether induced-depressed individuals demonstrate a mood congruence effect in unintentional learning is unknown. We manipulated 51 healthy participants into either a happy (n = 25) or a sad mood (n = 26) state and tested their mood-congruent information processing with unintentional learning of negatively charged picto..
- Common Gene Polymorphisms in the Mother of a Child Born with Neural Tube Defect and Down Syndrome
Abstract : The purpose of this communication is to report an unusual case of an infant affected with both neural tube defect (NTD) and Down syndrome (DS). Genetic risk factors in the mother were investigated. As impaired folate metabolism is implicated in the etiology of NTD and DS, folate gene polymorphisms were determined in th..
- Does Uterine Artery Doppler or Copper Intrauterine Device Location by Three Dimensional Transvaginal Ultrasound Correlates with Clinical Symptoms?
Abstract : Aim of study: To evaluate the effectiveness of using uterine artery color Doppler and location of intrauterine copper device by three dimensional transvaginal ultrasound in relation to abnormal vaginal bleeding and pain.Methods: Three dimensional transvaginal ultrasound examinations were carried out to 180 women 3-6 mo..
- Total Salpingectomy During Abdominal Hysterectomy Preserves Ovarian blood flow and Function
Abstract : Aim: To evaluate the effect of total salpingectomy on ovarian reserve and function during abdominal hysterectomy. Method: Twenty five patients undergoing total abdominal hysterectomy for dysfunctional uterine bleeding were randomly allocated into two groups; group (I) 13 patients undergoing total abdominal hysterectomy..
- Physical therapy or Platelet Rich Plasma Injections in the Treatment of Tennis Elbow: A Randomised Clinical Trial
Background: Chronic painful tendon disorders are common in athletic and sedentary individuals. They are common in middle age, and with increasing sports participation at increasing ages (1-4). Tendon regeneration may be improved by injecting autologous growth factors obtained from the patient’s own blood. Autologous growth facto..
- Signet-Ring Cell Change in Benign Prostatic Hyperplasia - A Rare Case Report
Abstract : Signet-ring cell change (SCC) is a non-neoplastic condition that morphologically simulates signet ring cell carcinoma (SRCC) both of which are rare entities in the prostate. Herewith, we report a case..
- Discarding the Newborn Babies in Malaysia
My opinion: Discarding the newborn babies had continued to escalate in Malaysia. A newborn baby was thrown into the dustbin at the Melaka General Hospital and was found dead on 18.08.2010. A ten month old baby was killed in dumped in the bus stand last week. The Social Welfare Department had recovered 315 discarded babies between ..
- Fish Disease Management in Integrated Farming System
Introduction: Integrated Fish Farming (IFF) is a sustainable-agriculture technology practiced widely in Asia and other regions of the world. This is very popular, advanced and widely practised in China. Hence most culture methods have either been derived from Chinese methods or modified suitably as per the regional requirements. Thi..
- In Vitro Antibacterial Activity of Lactobacillus Casei Against Enteropathogens
Abstract: Background: Lactic Acid Bacteria (LAB) produce various substances that exhibit antagonistic activity against other bacteria. These bacteria as well as the compounds secreted by them have increased attention since they have the potential to inhibit food related pathogens. Methods: Mild growth inhibitors secreted by Lact..
- Cord Blood Lactate and pH Values at Term and Perinatal Outcome: A Retrospective Cohort Study
Abstract: Objective: To examine the relationship between newborn umbilical cord blood lactate and pH levels, mode of delivery and short-term neonatal outcome. Materials and methods: Umbilical cord arterial and venous lactate and pH values, mode of delivery, birth weight, gestational age, Apgar scores were extracted from the Obst..
- Optimizing the Efficacy of Intercessory Prayer: Results from a Quadruply-Blind Study
Abstract : A large-scale study of the efficacy of intercessory prayer with 9,873 hospitalized patients has yielded positive results of a surprising character. IntroductionOver the years studies have tested the effectiveness of intercessory prayer going all the way back to an 1872 study1 by Francis Galton, the founder of statistic..
- Priapism Induced With Single Oral Dose Of Sildenafil: A Rare Case Report
Abstract : Phosphodiesterase enzyme inhibitors like Sildenafil citrate and tadalafil has revolutionised the treatment of erectile dysfunction. Priapism as a side effect of Sildenafil has been reported very rarely. We report a case of priapism caused by usual dose of Sildenafil..
- Antifungal activity of Rhein isolated from Cassia fistula L. flower
Abstract: Antifungal activity of rhein (1, 8- dihydroxyanthraquinone- 3carboxylic acid) isolated from the ethyl acetate extract of Cassia fistula flower was studied. Rhein inhibited the growth of many fungi such as Trichophyton mentagrophytes (MIC 31.25 µg/ml), Trichophyton simii (MIC 125 µg/ml), Trichophyton rubrum (MIC 62.5 ..
- Coal Power Station Installations and the Health of Populations: A Review of Evidence and State of the Art in Italy
Abstract : The link that exists between single pollutants and adverse reactions to health has been depicted as a pyramid. At its base are the most common consequences of exposure (increase in prevalence and incidence of respiratory diseases/symptoms and reduction in pulmonary function) and at the top is mortality. Although this l..
- Analysis of Volatile Omponents In Rhizome Zingibers, Zingiber Officinale Roscoe And Ginger Peel By Gas Chromatography-Mass Spectrometry And Chemometric Resolution
Abstract: The similarities and differences of essential oil components in rhizome zingibers(RZ)?zingiber officinale roscoe(ZOR) and ginger pee(GP) were investigated by GC-MS combined with a chemometric method named heuristic evolving latent projections(HELP).And temperature-programmed retention indices(PTRIs) was used together w..
- Community-Acquired Urinary Tract Infections in a Rural Area: Predominant Uropathogens, and their Antimicrobial Resistance
Abstract : Introduction: Urinary tract infections (UTIs) are among the most common bacterial infections and frequently recurring problems encountered by clinicians in community practice. The approach to these infections remains a difficult and sometimes controversial issue, especially in asymptomatic and symptomatic bacteruria. T..
- Adult Hemophagocytic Lymphohistiocytosis: A 25-Year Experience at a Tertiary Care Hospital
Abstract : Five patients of acquired Hemophago Lymphohistiocytosis (HLH) were seen in a tertiary care hospital over a period of 25 years. Three of the patients had a culture proved Salmonella typhi infection and..
- Current trends in the management of subacute sclerosing panencephalitis
Abstract : Subacute sclerosing panencephalitis (SSPE) is slow viral encephalitic sequlae occurring secondary to measles infection. Symptoms occur insidiously and progresses to coma and death. This condition carries a very high mortality. This article discusses the various drug therapies tried in this condition. The currently prov..
- The Need For Universal Neonatal Screening For Congenital Hypothyroidism In India
My opinion: Thyroid hormone plays a critical role in the development and maturation of the fetal brain.Deficient production of thyroid hormone or a defect in thyroid hormone receptor activity can lead on to hypothyroidism. Congenital hypothyroidism (CH) is one of the most common preventable causes of mental retardation in children..
- In vitro antimicrobial susceptibility against human and animal strains of the Chlamydia genus
Abstract : The in vitro activity of doxycycline, levofloxacin, moxifloxacin, azithromycin, clarithromycin, erythromycin, cotrimoxazole and rifaximin was tested against 81 strains of Chlamydia trachomatis, 12 str..
- Demons and spirits in the 3rd millennium - the haunting goes on
Abstract : Culture defines how individuals make meaning out of illness, suffering, and dying. Caring for patients with cross-cultural issues requires that they be well defined so that the clinician can navigate among cultural beliefs, values, and practices and increase the likelihood of successful therapeutic outcomes. One clinic..
- Perceptual and visuospatial abilities in chess players: a cross-sectional study
Abstract: The differences in ability of chess players at different skill levels to copy and to recall positions are attributable to the experts’ storage of thousands of chunks (patterned clusters of pieces) in the long-term memory.The aim of this study was to check differences in perceptual tasks and the visuo-spatial abstract..