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- Extreme Microcephaly, Diffuse Agyria, Agenesis of Corpus Callosum, Cerebellar Hypoplasia with Dandy-Walker Malformation: Is This A Severe Form (Barth Syndrome) or A New Variant of Microlissencephaly
Abstract: A five month girl with extreme microcephaly and complex brain malformation is reported. Magnetic resonance imaging (MRI) revealed bilateral thickened smooth cortex with diffuse agyria-pachygyria spect..
- Experimental Cancer Treatment: An Emerging Approach
Introduction: CancerCancer is a class of diseases in which a group of cells display uncontrolled growth (division beyond the normal limits), invasion (intrusion on and destruction of adjacent tissues), and sometimes metastasis (spread to other locations in the body via lymph or blood). These three malignant properties of cancers dif..
- Two New Cases of Uner Tan Syndrome: One Man with Transition from Quadrupedalism to Bipedalism; One Man with Consistent Quadrupedalism
Abstract: Background: Uner Tan syndrome, first described in 2005, consists of three main symptoms: habitual locomotion on all four extremities, impaired intelligence, and dysarthric or no speech. This extremely rare syndrome shows an autosomal recessive inheritance due to consanguineous marriages between parents. In general, the..
- Community-Acquired Urinary Tract Infections in a Rural Area in Jordan: Predominant Uropathogens, And their Antimicrobial Resistance
Abstract : Introduction: Urinary tract infections (UTIs) are among the most common bacterial infections and frequently recurring problems encountered by clinicians in community practice. The approach to these infections remains a difficult and sometimes controversial issue, especially in asymptomatic and symptomatic bacteruria. T..
- The Construct Validity and Internal Consistency of the Adult Learning Inventory (AL-i) among Medical Students
Abstract: Objective: To determine the internal consistency and construct validity of the AL-i among first year medical students. Methods: Cross sectional study was done on 196 first year medical student in Universiti Sains Malaysia (USM). The items of AL-i were framed based on the adult learning principles. The Cronbach’s a..
- The Learning Approach Inventory (LA-i): Its Reliability and Validity Among Medical Students
Abstract: Objective: To determine the internal consistency and construct validity of the Learning Approach Inventory (LA-i) among first year medical students.Methods: Cross sectional study was done on 196 first year medical students in Universiti Sains Malaysia (USM). The items of the LA-i were framed based on characteristics of..
- Measures of melatonin and cortisol variations in volunteers exposed to GSM cellular phones in a double blind experiment
Abstract: Melatonin and cortisol are two hormones produced according to a circadian rhythm. Cortisol is secreted in pulsatile manner, while melatonin blood concentration is influenced by the daylight; both are considered as stress markers. Animal studies suggest that exposure to ELF magnetic fields and radiofrequencies may influ..
- 21st Century Teaching For Students Of Medical Laboratory Technology: A Problem-Based Learning Approach
Abstract : Introduction: The expected knowledge base required for newly qualified laboratory technicians in practice setting is immense. However it is almost impossible to include all the information required at entry into professional practice into the teaching curricula. Problem based learning (PBL) is intended to develop lifel..
- A Three-Step Strategy To Approach The Public Benefit Basket In The Health-Care Systems Of Industrialized Nations
Abstract: In all health-care systems of industrialized nations it is difficult to describe the appropriate volume of services to be provided to all members of society. In our article, we propose a three-step strategy to facilitate decision making about this volume. This concept is based on the distinction between health-care ser..
- Polymerization Shrinkage Stress Reduction in Direct Occlusal Composite Restoration Placed Using Split-increment Horizontal Technique - Case Report
Abstract : Several incremental placement techniques have been introduced in an effort to reduce polymerization shrinkage stress associated with light curing of composite resins.In the horizontal technique, place..
- Introduction to Cofilin and its Regulation of Actin Dynamics
Introduction: Actin is the most abundant protein in eukaryotic cells (Bamburg and Wiggan 2002). Cytokinesis, endocytosis, chemotaxis and neurite growth are examples of cellular processes that depend on polymerization of actin filaments (Carlier et al 1999). In order for cell motility to occur, there has to be a combination of elonga..
- Exposing a Loophole: Journals Not Requiring Ethics Committee Review for Published Meeting Abstracts
Abstract: Purpose: Medical journals have become increasingly explicit in their requirements for ethics committee review of human research. However, many medical societies do not require ethics review for human research submitted as abstracts and presentations; often these abstracts are then published in affiliated journals. This..
- An efficient approach to Enrich Glioma Stem Cells from Glioma Cell Lines in Culture
Abstract: Within a glioma tumor mass and even in established glioma cell lines, resides a sub-population of cells known as glioma stem cells. These cells are postulated to contribute significantly to the treatm..
- How could a Basic Knowledge of Vascular Physiology Provide a New Tool for Tumor Oxygen-induced Radiosensitization- Postocclusive Reactive Hyperemia Concept for Synchronized Radiotherapy
Abstract: Tumor angiogenesis leads to the development of pathologic vessels and blood flow insufficiency that results in tumor hypoxia, which can be an obstacle for effective radiotherapy. Tumor perfusion enhan..
- Promoting integrated learning and open-book examinations in South Asian medical schools
My opinion: South Asia has a good proportion of the world’s medical schools and creates a large percentage of the world’s health manpower. The examination pattern remains largely traditional and emphasizes factual knowledge and mastery of information. Rote learning is emphasized throughout school in South Asia. Educational ob..
- Atresia And Congenital Short Gut
Discussion: Short gut syndrome is associated with life long problems of absorption, intestinal motility, and growth. Short gut syndrome may be congenital or acquired. We report a case of type III jejunal atresia ..
- The Use of Metal Detectors as a Tool for Diagnosing Ingested Metal Foreign Bodies- A Review
Abstract : Coins are frequently ingested by young children in the UK. X-Radiographs have been considered as the gold standard of detecting any swallowed metal foreign bodies in order to ascertain subsequent management. The cost of radiographs, high proportion of normal radiographs and potential long term hazards11 of ionising rad..
- An Approach to the Detection of Mycobacteria in Clinically Suspected Cases of Urinary Tract Infection in Immunocompromised Patients
Abstract : Urinary tract infections (UTIs) are one of the most common infections in human beings. Most of these infections are caused by bacterial agents. Mycobacterial agents causing UTIs are less frequent in immunocompetent individuals; they are more common and severe in immunocompromised individuals.The incidence of tuberculos..
- Review Of Biological Activities Of " Tinospora Cordifolia "
Abstract : Tinospora cordifolia is one of the constituents of several ayurvedic preparations used in general debility, dyspepsia, fever and urinary diseases. The stem is bitter, stomachic, diuretic, stimulates b..
- The Issues of Incapacity to Give Consent
Abstract : The words capacity and competence are often used interchangeably within the modern day, however strictly speaking competency is the legal term for capacity to give evidence. Those above the age of 18 ..
- Use Of Information Technology In Medical Education
My opinion: Background The Information Technology Association of America (ITAA) defines Information Technology (IT) as "the study, design, development, implementation, support or management of computer-based info..
- Adenoma Of The Nipple In A Man: Case Report
Abstract : Adenomatosis (adenoma, papillary adenoma, florid papillomatosis) of the nipple is a rare benign disorder involving the nipple witch can be mistaken clinically for Paget's disease and pathologically be misinterpreted as an adenocarcinoma. It occurs mostly in middle-aged women and is extremely rare in adolescents and chi..
- Pagets Disease Of The Nipple
Case Discussion: A 38-year-old female diagnosed and treated for wet eczema of left nipple for 3 months was referred for further management due to failure of the dermatological management. The patient had no other symptoms and general examination was unremarkable. Local examination of the left breast revealed weeping dermatitis involvin..
- Epistaxis With Oseltamavir
Introduction: Oseltamavir is now being used on a large scale across the globe and this will contribute to the advancement of knowledge about side-effects and adverse events associated with use of oseltamivir. We would like to share our experience with regard to occurrence of epistaxis in two patients who were put on oseltamivir ther..
- "Radio-Ulnar Synostosis Following Isolated Fracture Of Shaft Of Ulna And Its Treatment By Radical Excision And Interposition Of Tensor Fascia Lata Graft"
Abstract : Radioulnar synostosis is a well recognized and disabling complication of fractures of forearm bones; however it is very rare following single forearm bone fracture. Excision of synostosis alone carrie..
- Preventive impact of alkaloids with anti-cancer effect extracted from natural herb and the derivatives
Abstract: BackgroundAlkaloids with pharmacological effects are often used as medications and recreational drugs, and are a group, which is one of the major elements of herbal medicine. The theme of this study i..
- Supracondylar Fracture of the Femur in Children
Abstract : Objective:A retrospective review of 59 supracondylar femoral fractures occurring in 56 children between1991 and 2004 (14 years) was performed to assess treatment methods and outcomes.Design:Patient ag..
- Spinal Cord Tumors That Present as Chronic Abdominal Pain: Analysis of the Literature
Abstract : Background: Chronic abdominal pain without a structural or metabolic gastroenterological etiology can be extremely challenging to diagnose and treat. Patients presenting with an associated radicular p..
- Anesthetic Management Of A Patient With Tetra-Amelia Syndrome
Abstract : Tetra-amelia Syndrome is a very rare autosomal genetic disorder characterized by the complete absence of all extremities with associated anomalies. Anesthetic management of these patients may be challenging, including problems with vascular access, lack of sites available to monitor blood pressure and possible difficul..
- An Approach to Linezolid and Vancomycin against Methicillin Resistant Staphylococcus Aureus
Abstract: In vitro activities of linezolid and vancomycin which were evaluated against methicillin resistant Staphylococcus aureus (MRSA). One hundred clinical isolates of MRSA were collected. The minimum inhibitory concentrations (MICs) of linezolid and vancomycin were determined by the Epsilon-test method. The results showed 1..
- Remodelling Through The Growth Plate- An Experimental Study In Rats
Abstract: The ability of the skeleton to remodel itself has long been recognized and studied. There has been great controversy among scientists as to whether remodeling takes place mainly in the fracture site o..
- Characterization Of Mucoadhesive Tablets Of Ciprofloxacin
Abstract: Ciprofloxacin is a fluoroquinolones antibiotic used for the treatment of IBD and specific complication of Crohn’s disease. Ciprofloxacin inhibit M. fortuitum, M. kansaii and M. tuberculosis. Ciprofloxacin is effective for the treatment of prostatitis caused by sensitive bacteria. Oral dose in adults are 250-750mg. Pl..
- Placebo Prescribing Habits And Views In A University Hospital
Abstract : Background and Objective There are no reports about Placebo Prescribing Habits among Saudi health care providers. This study aims addressing this question.Methods This is a cross-sectional self administered survey-based study about frequency, views and indications, of placebo prescribing/dispensing practices and analyz..
- Participatory Community Mapping: A Tool To Enhance Psychosocial Wellbeing
Abstract : This articles proposes that community participatory mapping is a valuable tool in developing psychosocial support activities after a disaster or emergency. Throughout the text examples from the field are provided to support the suggestions given...
- Split Notochord Syndrome With Neuroenteric Fistula, A Rare Malformation
Abstract : Split notochord syndrome (SNS) with neuroenteric fistula (NEF) is a very rare congenital malformation involving spinal cord, vertebral column and gastrointestinal tract (GIT). A 5-hour old male newbor..
- The Reliability And Validity Of The Postgraduate Stressor Questionnaire (psq) Among Postgraduate Medical Trainees
Abstract: Objective: To determine the construct validity and the internal consistency of the Postgraduate Stressor Questionnaire (PSQ) among postgraduate medical trainees hence in the future it could be used as a valid and reliable instrument to identify stressors among them. Methods: Items of the PSQ were derived from a review ..
- Intestinal Obstruction Secondary To Duodenal Gastrointestinal Stromal Tumour
Abstract : Though gastrointestinal stromal tumours are common, a duodenal stromal tumour is a rare entity. We present such a rare case with duodenal obstruction which caused a dilemma in the management of this patient. Though a Whipple’s operation was planned, intraoperatively, due to the pedunculated nature and free intralumin..
- A Tooth Is Worth A Treasure
Characters from the Pages of Literature Visit the Dentist: Abstract Dentistry has captured the hearts and minds of both the greatest masters of literature and their audiences throughout the ages.Like real-life dentistry, the characters of literature pose different diagnostic challenges, have different ideas of what they desire for their teeth, have various medical issues and c..
- Antioxidative And Free Radical Of Limonium Axillare From Qatarian Coasts
Abstract : In the present study, we carried out the antioxidant and antiradical activity of a methanol extract from the leaves of the halophyte plant Limonium axillare (family: Limoniaceae, order: Plumbaginales). Antiradical activity was determined using 1, 1-diphenyl-2-picrylhydrazyl (DPPH) method and antioxidant activity was ch..
- Diplopia Secondary To West Nile Virus Meningitis
Abstract : Cranial nerve involvement has been reported with West Nile Virus infection. We report a case of diplopia secondary to West Nile Virus meningitis...
- Hypothesis, Inserting Bacterial Natural Transformation Protein Complexes Into Human Cells For Efficient Gene Therapy Using Naked Dna
Abstract: Naked DNA is a non-toxic vector for therapeutic gene delivery. However, current methods of transfection with naked DNA reach a limited range of susceptible tissues and have a low efficiency. The transfection of clinically important post-mitotic cells is particularly challenging because in these cells DNA need to pass t..
- An Association Between Serum Cortisol Levels In Erosive And Nonerosive Oral Lichen Planus Patients
Abstract : Study objectives: Oral lichen planus (OLP) is a well recognized chronic mucocutaneous disorder which can manifest in the oral mucosa, whose exact pathogenic mechanisms have not been understood. Estimation of serum cortisol in patients with OLP may be helpful in understanding the pathogenesis. Therefore a study was unde..
- The Evolution Of Alu Mutations In The Human Genome
Abstract: The article reports the frequency distributions of the mutants of Alu elements in the human genome. They are remarkably complex and, yet, almost identical for each chromosome, suggesting a universal mechanism for base substitutions in Alu-elements and, possibly, other retro-transposons as well. Conceivably, these mutat..
- The Glycemic Pentad: Role Of Insulin Analogues
Introduction: Achieving glycemic control is the main aim of diabetes care, and near euglycemic levels are targeted to minimize the risk of developing chronic complications of the condition. Large trials have demonstrated the benefits of glycemic control in both type 1 and type 2 diabetes (1,2).Good glycemic control means effective t..
- Stomatologic Prosthesis In Management Of Maxillary Resection For Carcinoma Of Maxillary Antrum : A Case Report
Abstract : Malignant tumours of nasal cavity and para nasal sinuses have a low incidence rate. Management of maxillary malignancies and/or surrounding structures necessitates the removal of partial or total maxi..
- Primary Chondrosarcoma Of The Breast: A Case Report
Abstract : Sarcomas of the breast are relatively rare and account for 1% of all primary malignant tumors of the breast. We present a case of a pure chondrosarcoma of the breast in a fifty-four-year-old man. Hist..
- Glomus Jugulare: A Case Of Secretory Glomus Jugulare With Review Of Literature
Abstract : We report a case of secretory glomus jugulare tumor in a 65 year old female who presented with hearing impairment, pulsatile tinnitus, from 3 years and difficulty in swallowing, hoarseness of voice and palpitation from last six months. Detailed history and examination with aid of investigations it turned out secretory ..
- Neurogenic Pulmonary Edema -the Lurking Peril
Abstract: The authors report on a patient with acute obstructive hydrocephalus due to cerebellar meatastatic lesion who presented with neurogenic pulmonary edema. The edema resolved on placement of the ventriculoperitonial shunt. Because neurogenic pulmonary edema may be a unrecognised consequence of obstructive hydrocephalus, i..
- Resolution And Improvement Of Type 2 Diabetes Mellitus After Rygb
Abstract : Introduction: Several studies have reported a dramatic improvement in type 2 diabetes mellitus (T2DM) just days after bariatric surgery, with a reduction of fasting glucose, serum insulin and rate of progression of the disease. Not all bariatric procedures are equally effective in resolving or improving T2DM. Bilio pan..
- Supracondylar Process Congenitalis Of The Femur
Abstract : The author reports a case of supracondylar process of the femur in a patient who presented with trauma to the left knee in a road traffic accident. The patient was not symptomatic and the process was ..