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Prof. Gyula Szigeti

Professor, Vice-Director
Hungarian Scientific Research Fund

Brief Biography:

Ph.D., University of Debrecen, Physiology and Neurobiology, 2001.

M.D., University of Debrecen, General Medicine, 1993.

MSc., Health Care Management, 2006


2008-2009, Associate Professor, Semmelweis University, Human Physiology

2004-2008, Assistant Professor, University of Debrecen, Health and Science Center, Physiology

2002-2003, Assistant Professor, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Physiology and Biophysics

2001-2004, Assistant Lecturer, University of Debrecen, Health and Science Center, Physiology

2001-2002, Postdoctoral Fellow, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Physiology and Biophysics

2000-2000, Postdoctoral Fellow, Pennsylvania State University, CVPRI

1998-2000, Postdoctoral Fellow, MCP Hahnemann University, Allegheni General Hospital, CVPRI

1998-1998, Research Associate, University of Cincinnati, Pharmacology and Cell Biophysics

1996-1997, Family Practice, Pocsaj

1995-1995, Research Fellow, University of Cologne, Medical School, Internal Medicine

1994-1995, Resident, General Community Hospital

1993-2001, Research Associate, University of Debrecen, Health and Science Center, Physiology.


Academic positions:

Hungarian Scientific Research Fund

OTKA Office, Vice-Chair

Appointed: 2009

Semmelweis University

Human Physiology, Associate Professor

Appointed: 2008

Celsus Ltd

Chief of R+D Division

Appointed: 2007

Journal of Complementary and Alternative Medicine

(Komplementer Medicina)


Appointed: 2007


Research interests:

Electrophysiology: one-electrode patch-clamp (whole-cell and single-channel configuration) onisolated excitable (e.g. myocytes) and non-excitable (e.g. keratinocytes) cells or cell culture (e.g.cardiomyocyte, myotube, COS7, HEK cells), two-electrode patch-clamp (oocyte), perforatedpatch

Optical techniques: intracellular Ca2+ measurement on attached and suspended cells withphotomultiplier and image, combined patch-clamp and Fura-2 measurement on excitable andnon-excitable cells. Confocal microscopy.

Whole organ model techniques: cardiovascular experiments on working myocardium withLangendorff-preparatum, intracellular Ca2+ measurement on whole working heart

Computer technique and analysis: computer programming (Basic, Visual Basic, Access, html),mathematical modeling of biological systems (e.g. cardiac action potential, axon action potential,pH regulation), non-linear analysis and modeling (e. g. fractals, EEG), statistical methods andanalysis (Microsoft Office, Origin 2.8-6.0, pClamp 5.5-8.0)

Cell physiology, pharmacology and cell biology: isolation technique of cardiomyocytes (humanatrial and ventricular, rat, mouse, rabbit, guinea-pig, ferret, pig and dog; retrograd perfusion,segment perfusion, chunk method for biopsy) and smooth muscle cells, proliferation assays([3H]thymidine incorporation) intracellular second messenger determination (cAMP, cGMP, IP3)assay.

Health-care Management

Quality Control in Health and Education

Development new food supplements

Antifungal drug development and control.


Any other information:

2007, Öveges award, KPI, Hungary

2006, Annual award of the Hungarian Physiological Society, Hungarian Physiological Society

2005, Annual award of the Society for healing of sceletal muscle disorders, Society for healing of skeletal muscle disorders, Hungary

2003, Bolyai Fellowship, MTA

2003, Buswell Fellowship, State University of New York at Buffalo, University at Buffalo

1998, Annual Award of the Hungarian Society of Cardiology, Hungarian Society of Cardiology

1996, The Best Scientific Lecture, Ph.D. Student section, University of Debrecen, Hungary

1996, Libra Pharmacy's Award, Libra Pharmacy

1994, "Oláhné Mezei Róza" Award, University of Debrecen, Hungary

1991, Computer modelling award, Neuman János Computer Society, Hungary

1991, Annual Student Scientific Award, Informatics, OTDK, Hungary.


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