Brief Biography:
Ph.D., University of Debrecen, Physiology and Neurobiology, 2001.
M.D., University of Debrecen, General Medicine, 1993.
MSc., Health Care Management, 2006
PREVIOUS POSITIONS:
2008-2009, Associate Professor, Semmelweis University, Human Physiology
2004-2008, Assistant Professor, University of Debrecen, Health and Science Center, Physiology
2002-2003, Assistant Professor, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Physiology and Biophysics
2001-2004, Assistant Lecturer, University of Debrecen, Health and Science Center, Physiology
2001-2002, Postdoctoral Fellow, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Physiology and Biophysics
2000-2000, Postdoctoral Fellow, Pennsylvania State University, CVPRI
1998-2000, Postdoctoral Fellow, MCP Hahnemann University, Allegheni General Hospital, CVPRI
1998-1998, Research Associate, University of Cincinnati, Pharmacology and Cell Biophysics
1996-1997, Family Practice, Pocsaj
1995-1995, Research Fellow, University of Cologne, Medical School, Internal Medicine
1994-1995, Resident, General Community Hospital
1993-2001, Research Associate, University of Debrecen, Health and Science Center, Physiology.
Academic positions:
Hungarian Scientific Research Fund
OTKA Office, Vice-Chair
Appointed: 2009
Semmelweis University
Human Physiology, Associate Professor
Appointed: 2008
Celsus Ltd
Chief of R+D Division
Appointed: 2007
Journal of Complementary and Alternative Medicine
(Komplementer Medicina)
Editor-in-Chief
Appointed: 2007
Research interests:
Electrophysiology: one-electrode patch-clamp (whole-cell and single-channel configuration) onisolated excitable (e.g. myocytes) and non-excitable (e.g. keratinocytes) cells or cell culture (e.g.cardiomyocyte, myotube, COS7, HEK cells), two-electrode patch-clamp (oocyte), perforatedpatch
Optical techniques: intracellular Ca2+ measurement on attached and suspended cells withphotomultiplier and image, combined patch-clamp and Fura-2 measurement on excitable andnon-excitable cells. Confocal microscopy.
Whole organ model techniques: cardiovascular experiments on working myocardium withLangendorff-preparatum, intracellular Ca2+ measurement on whole working heart
Computer technique and analysis: computer programming (Basic, Visual Basic, Access, html),mathematical modeling of biological systems (e.g. cardiac action potential, axon action potential,pH regulation), non-linear analysis and modeling (e. g. fractals, EEG), statistical methods andanalysis (Microsoft Office, Origin 2.8-6.0, pClamp 5.5-8.0)
Cell physiology, pharmacology and cell biology: isolation technique of cardiomyocytes (humanatrial and ventricular, rat, mouse, rabbit, guinea-pig, ferret, pig and dog; retrograd perfusion,segment perfusion, chunk method for biopsy) and smooth muscle cells, proliferation assays([3H]thymidine incorporation) intracellular second messenger determination (cAMP, cGMP, IP3)assay.
Health-care Management
Quality Control in Health and Education
Development new food supplements
Antifungal drug development and control.
Any other information:
2007, Öveges award, KPI, Hungary
2006, Annual award of the Hungarian Physiological Society, Hungarian Physiological Society
2005, Annual award of the Society for healing of sceletal muscle disorders, Society for healing of skeletal muscle disorders, Hungary
2003, Bolyai Fellowship, MTA
2003, Buswell Fellowship, State University of New York at Buffalo, University at Buffalo
1998, Annual Award of the Hungarian Society of Cardiology, Hungarian Society of Cardiology
1996, The Best Scientific Lecture, Ph.D. Student section, University of Debrecen, Hungary
1996, Libra Pharmacy's Award, Libra Pharmacy
1994, "Oláhné Mezei Róza" Award, University of Debrecen, Hungary
1991, Computer modelling award, Neuman János Computer Society, Hungary
1991, Annual Student Scientific Award, Informatics, OTDK, Hungary.
What I think of the idea behind WebmedCentral:
Home Page:
http://myprofile.cos.com/dr_szigyu