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Prof. Maciej Cedzynski

Associate Professor, Head of Laboratory
Laboratory of Immunobiology of Infections, Institute of Medical Biology, Polish Academy of Sciences
Lodowa 106
 

Brief Biography:


Name: Maciej Cedzynski
Address for correspondence: Institute of Medical Biology, Polish Academy of Sciences, Lodowa 106, 93-232 Lodz, Poland;

Education:
* MSc (biology, microbiology) – 1990, University of Lodz, Faculty of Biology and Earth Sciences
* PhD (biological sciences, biology, microbiology) – 1996, University of Lodz, Faculty of Biology and Earth Sciences Dr habil. (medical sciences, medical biology, immunology) – 2005, Medical University of Lodz, Faculty of Military Medicine

Major publications (2007 – 2012):
1. A. St. wierzko, K. Florczak, M. Cedzynski, J. Szemraj, D. Wydra, L. Bk-Romaniszyn, J. Emerich, Z. Suowska: Mannan-binding lectin (MBL) in women with tumours of the reproductive system, 2007, Cancer Immunol. Immunother., (56), 959-971
2. M. Cedzynski, L. Nuytinck, A. P. M. Atkinson, A. St. wierzko, K. Zeman, J. Szemraj, A. Szala, M. L. Turner, D. C. Kilpatrick: Extremes of L-ficolin concentration in children with recurrent infections are associated with single nucleotide polymorphisms in the FCN2 gene, 2007, Clin. Exp. Immunol., (150), 99-104
3. M. Cedzynski, K. Madaliski, H. Gregorek, A. S. wierzko, E. Nowicka, K. Obtuowicz, K. Dzieranowska-Fangrat, U. Wojda, D. Rabczenko, M. Kawakami: Possible disease-modifying factors: the mannan-binding lectin pathway and infections in hereditary angioedema of children and adults, 2008, Arch. Immunol. Ther. Exp., (56), 69-75
4. A. St. wierzko, A. P. M. Atkinson, M. Cedzynski, S. L. MacDonald, A. Szala, I. Domalska-Popadiuk, M. Borkowska-Kos, A. Jopek, J. Szczapa, M. Matsushita, J. Szemraj, M. L. Turner, D. C. Kilpatrick: Two factors of the lectin pathway of complement, L-ficolin and mannan-binding lectin, and their associations with prematurity, low birthweight and infections in a large cohort of Polish neonates, 2009, Mol. Immunol., (46), 551-558
5. A. St. wierzko, A. Szala, M. Cedzynski, I. Domalska-Popadiuk, M. Borkowska-Kos, A. Jopek, J. Szczapa, J. Szemraj, A. P. M. Atkinson, S. L. MacDonald, M. L. Turner, D. C. Kilpatrick: Mannan-binding lectin genotypes and genotype-phenotype relationships in a large cohort of Polish neonates, 2009, Hum. Immunol., (70), 68-72
6. A. St. wierzko, M. Cedzyski, I. Domalska-Popadiuk, S. L. MacDonald, M. Borkowska-Kos, A. P. M. Atkinson, A. Szala, A. Jopek, J. C. Jensenius, M. Kawakami, J. Szczapa, M. Matsushita, J. Szemraj, M. L. Turner, D. C. Kilpatrick: Mannan-binding lectin-associated serine protease-2 (MASP-2) in a large cohort of neonates and its clinical associations, 2009, Mol. Immunol., (46), 1696-1701
7. M. Pertyska-Marczewska, M. Cedzynski, A. wierzko, A. Szala, M. Sobczak, K. Cypryk, J. Wilczyski: Evaluation of lectin pathway activity and mannan-binding lectin levels in the course of pregnancy complicated by diabetes type 1 based on the genetic background, 2009, Arch. Immunol. Ther. Exp., (57), 221-228
8. M. Cedzynski, A. P. M. Atkinson, A. St. wierzko, S. L. MacDonald, A. Szala, K. Zeman, K. Buczyko, L. Bk-Romaniszyn, M. Wiszniewska, M. Matsushita, J. Szemraj, M. Banasik, M. L. Turner, D. C. Kilpatrick: L-ficolin (ficolin-2) insufficiency is associated with combined allergic and infectious respiratory disease in children, 2009, Mol. Immunol., (47), 415-419
9. A. Szala, E. Paradowska, D. Nowakowska, A. S. wierzko, K. Dzieranowska-Fangrat, A. Sokoowska, M. Studziska, Z. Gaj, P. Suski, B. Kasztelewicz, J. Wilczyski, M. Cedzynski: Mannan-binding lectin-2 (MBL2) gene polymorphism in prenatal and perinatal cytomegalovirus infection, 2011, Mol. Immunol., (48), 2203-2206
10. L. Bk-Romaniszyn, A. Szala, A. Sokoowska, G. Mierzwa, M. Czerwionka-Szaflarska, A St. wierzko, K. Zeman, M. Cedzynski: Mannan-binding lectin (MBL) deficiency in pediatric patients with inflammatory bowel disease, 2011, Scand. J. Gastroeneterol., (46), 1275-1278
11. A. wierzko, J. ukasiewicz, M. Cedzynski, A. Maciejewska, W. Jachymek, T. Niedziela, M. Matsushita, C. ugowski: New functional ligands for ficolin-3 among lipopolysaccharides of Hafnia alvei, 2012 (e-pub. 02.09.2011), Glycobiology, (22), 267-280
12. M. Michalski, A. Szala, A. St. wierzko, J. ukasiewicz, A. Maciejewska, D. C. Kilpatrick, M. Matsushita, I. Domalska-Popadiuk, M. Borkowska-Kos, A. Sokoowska, J. Szczapa, C. ugowski, M. Cedzynski: H-ficolin (ficolin-3) concentrations and FCN3 gene polymorphism in neonates, 2012, Immunobiology, in press
13. M. Cedzynski, A. St. wierzko, D. C. Kilpatrick: Factors of the lectin pathway of complement activation and their clinical associations in neonates, 2012, J. Biomed. Biotechnol., in press International exchange: Robert-Koch Institut, Wernigerode, Germany – scientific guest (1992, 6 weeks) Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia – visiting researcher (1997, 2 weeks) Institute of Virology, Slovak Academy of Sciences, Bratislava, Slovakia – visiting researcher (2000, 1 week) Scottish National Blood Transfusion Service, National Science Laboratory, Edinburgh, Great Britain – visiting researcher (2005, 2007, 2011 - 1 week each)

Awards and honours:
* Award of Rector of the University of Lodz , 1986, 1987, 1989, 1990
* Medal for the best graduate student, University of Lodz, 1990
* FEMS fellowship to attend the IIIth Conference of International Endotoxin Society, Helsinki, 1994
* Fellowship of the Foundation for Polish Science for outstanding young scientists, Warszawa, 1996
* Vice president of the Lodz board of Polish Society for Microbiology, 1996-2000
* IUIS award for young scientists – to attend 11th International Congress of Immunology, Stockholm, 2001)
* Chairman of the Committee for Receiving and Conducting Doctoral Exams – Institute of Medical Biology, PAS (since 2008)

 

Academic positions:


* 2006 – present: Laboratory of Immunobiology of Infections, Institute of Medical Biology (till 2008: Centre of Medical Biology), Polish Academy of Sciences; assoc. prof., head of laboratory
* 2004 – 2006: Laboratory of Immunobiology of Infections, Centre of Medical Biology, Polish Academy of Sciences; assist. prof., head of laboratory
* 1999 – 2003: Laboratory of Immunobiology of Infections, Centre of Microbiology and Virology, Polish Academy of Sciences; assist. prof., head of laboratory
* 1996 – 1999: Laboratory of Cell Structures, Centre of Microbiology and Virology, Polish Academy of Sciences; assist. prof.
* 1992 – 1996: Laboratory of Cell Structures, Centre of Microbiology and Virology, Polish Academy of Sciences; senior res. assist.
* 1990 – 1991: Laboratory of Cell Structures, Centre of Microbiology and Virology, Polish Academy of Sciences; res. assist.

 

Research interests:


Innate immunity- especially lectin pathway of complement activation, collectins, ficolins and associated serine proteases.

 

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