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ABSTRACT: Each New Drug Application filed with the Food and Drug Administration (FDA) must include the analytical procedures to  ensure the identity, strength, quality, purity, and potency of a drug substance and drug product. The BSN389 drug product (being developed  to treat Ebola virus infections) includes beta cyclodextrin..

Abstract: Combination therapy is beneficial treatment modality for multiple diseases. Cinnamon oil may be an advantageous agent in a number of combination therapies as cinnamon oil has antibacterial activity. Cinnamon oil has also been shown to be effective against biofilm cultures of Streptococcus mutans and Lactobacillus plant..

ABSTRACT: The purpose of this research is to choose the best analytical method for determining stability of BSN175. This research uses an accelerated stability study to compare the decomposed and stable drug using IR and 1H NMR spectroscopy. The Bootstrap Error-adjusted Single-sample Technique (BEST) was used to compare the effe..

My opinion: I am addicted to reading because I am addicted to exploring. Recently I read three books, not in a particular sequence, which aligned my line of thought to a tee. The first book was The Alienist by Caleb Carr [1], read after religiously watching television series, The Alienist on TNT [2], a cable television network. Th..

Abstract: The prevalence of overlays (overwriting) in electronic medical record (EMR) system has been well established. The literature is abundant in regards to the consequences of overlays for patient safety, the technical costs of cleaning EMR from its overlays, and the essentiality to prevent overlays. However, it is not clea..

Abstract: Background Uterine leiomyomas, the most common benign gynecological tumor, usually occur in females of reproductive age. Myomectomy is the preferred surgical treatment in reproductive-aged women who want to retain their uterus. Myomas can range in size from as small as an apple seed to as large as a melon. Giant uterin..

Abstract : Induction of labour is a common obstetric procedure. At present, different methods are used for induction of labour in women. One of these methods is Foley catheter, which is a low cost method that can induce labour with less risk to the fetus. This is one of the first studies in the Middle East aiming to study efficac..

Abstract: Supracondylar femur fractures in adults is a complex fracture constitutes approximately 1% of total fractures and 4-7% of all femoral fractures (Kolmert, 1982)1. There is a bimodal distribution, with young patients with high energy trauma and elderly patients with low-energy falls. Approximately 85% of these fractures ..

Abstract: Introduction: Uner Tan syndrome (UTS) consists of quadrupedal locomotion (QL), impaired intelligence and dysarthric or no speech. Previously, I described the walk of cases with UTS as diagonal sequence (DS) because of ipsilateral limb interference, mostly observed in nonhuman primates with DS QL. The only gait analysis..

Abstract : Coccyx pain (also called coccydynia, or tailbone pain) has a broad range of etiologies, including traumatic and non-traumatic causes. Iatrogenic etiologies of coccydynia are rarely reported. This is the first report of iatrogenic coccydynia due to the use of a chiropractic actuator. An actuator (also known as an activa..