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- An Overview of Changing Trends in Systemic Fungal Infections
Abstract : Background:Invasive mycoses are a significant and growing public health problem. The increasing use of invasive monitoring and aggressive therapeutic technologies in intensive care units has resulted in improved survival of individuals with life-threatening illnesses, but has also contributed to an increase in number o..
- Piracetam (2-Oxo-Pyrrolidone) Advance and Modulate Central Processing Reaction Time in Normal Healthy Volunteers: Randomized Experimental Study; Single Blind Clinical Trail
Abstract : The present study was designed to show the effect of piracetam (2-Oxo-Pyrrolidone) on simple reaction time. This study involved 30 healthy volunteers which were recruited from medical college students (20 males and 10 females) .The reaction time was measured by ruler dropper test method, and by this method we can deter..
- Assessment of Third Ventricle with MRI: Morphological Variations Among Different Gender and Age Group
Abstract : Objectives: The aim of the morphometric study was to examine the range in the normal size of the third ventricle in the North Indian population; males and in females living in Punjab and, assess the existence of its relationship with gender and age; and clinically correlate. Materials and Methods: MRI of 300 subjects l..
- Recurrent Fibrolipoma of the Left Thigh - A Case Report
Abstract : A 43 year old male presented with giant fibrolipoma of the left thigh, recurrent for the 4th time. On contrast CT & MRI the tumor had massive adipose and non adipose components and enhanced heterogene..
- Autoamputation of Congenital Hairy Polyp in Neonate with Stridor and Respiratory Failure
Abstract : Hairy polyp of the oronasopharynx is a rare developmental malformation. It is usually seen as a pedunculated tumor in the neonate. It is classified as a dermoid since it is derived from the ectoderm ..
- Life Expectancy and Comparative Mortality of Major League Baseball players, 1900-1999.
Abstract: Several studies have documented increased life expectancy and improved mortality for Major League Baseball players, but none has yet provided a complete analysis of baseball player mortality patterns ..
- Prosthetic Rehabilitation of Maxillofacial Trauma Patient - A Case Report
Abstract : Rehabilitation of maxillofacial trauma patients is a challenging task. The most common prosthetic treatment problem with such patients is, getting adequate retention, stability and support. The size a..
- The Cost-Effectiveness and Competency Untold - An Analysis of Medical Tourism in Kerala with reference to Allopathic Medicine
Abstract: The key benefits of medical tourism in the ‘God’s Own Country’ are relatively competitive prices, quality, timely and personal care. The article unveils the cost difference between Kerala and other cities and compares with the main competitors like US and Thailand. Primary concerns are quality care, which include..
- Importance of Sample Size Calculation in the Original Medical Research Articles from Developing Countries
Abstract : Sample size calculation is very important for medical research. Because medical data is with uncertainty and most of the studies deals with a small sample and infer about a big population. But most of the researchers from developing countries like Nepal are not aware about this and who aware are not able to use this ..
- Relevance of Post or Pre Peer Review Process Journals for the improvement of Medical Research in Nepal
Abstract : Despite valuable research going on in developing countries like Nepal and the large number of existing scientific journals, this information does not reach international visibility. Not only are such journals obscure, but they also perpetuate a vicious circle of inadequacy that may directly be damaging the local scienc..
- Unreamed Solid Locked Nailing in the Treatment of Compound Diaphyseal Fractures of Tibia
Abstract: This is a prospective study based on 30 cases of compound tibial diaphyseal fractures fulfilling our inclusion criteria and stabilised with primary unreamed solid AO tibial locked nailing with a follow up ranging from 6-18 months. Open fractures were classified as per Gustillo’s. Road traffic accidents were responsib..
- A Case of Bilateral Optic Neuritis
Abstract : A 22 year male patient presented with headache fever and vomiting since 3 days duration and was initial managed as a case of meningitis or suspected brain abscess. He developed painful blurred vision ..
- Advanced Breast Cancer with Cerb2 Over Expression - A case Report
Abstract : A 53year old female presented with advanced carcinoma of the right breast with clinically positive right axillary lymph node. Triple assessment was done. FNAC confirmed ductal cancer, mammography sh..
- Assessment of Anti-Inflammatory and Analgesic Activities of Callicarpa Macrophylla Vahl. Roots Extracts
Abstract: Callicarpa macrophylla, an indigenous plant of India, had been the plant of study for the current research work. Aqueous as well as ethanolic extracts of its roots(at two concentrations 200 & 400 mg/kg) were evaluated for its analgesic and anti-inflammatory potentials using tail immersion test and carrageenan paw edema..
- Randomisation and blinding in clinical trials
Abstract : High quality clinical trials are designed to reduce bias, to increase the confidence that the reader can place in the conclusions of the trial. This article evaluates the role of randomisation and blinding to prevent bias and how to best implement them in a trial...
- The Pharmacokinetics of Alcohol in Healthy Adults
Abstract : Alcohol is a commonly used drug that has many important health consequences. To understand its physiological effects and predict drug interactions it is important to understanding alcohol’s pharmacokinetics and the factors that influence it. A brief review of the absorption, distribution, metabolism, and excretion of..
- The Effects of Sprint Interval Training on Aerobic Fitness: A Systematic Review
Abstract : Background: Greater aerobic fitness is associated with improved cardiovascular health. Traditionally high volume (long duration and low intensity) endurance training (ET) has been used to increase aerobic fitness. Sprint interval training (SIT) is a low volume and high intensity form of interval training. Energy for SI..
- Why Adverse Drug Events occur and what can be done to avoid them.
Abstract : This article reviews the prevalence and importance of adverse drug events. The mechanisms that lead to ADE are explored and strategies to prevent them are discussed...
- Detection of a Point Mutation at Codon 12 of the Kirsten-Ras (K-ras) Oncogen in Myelodysplastic Syndrome
Abstract: Mutations in ras genes have been observed in a variety of cancers and were found to play an important role in human leukemogenesis and in preleukemic disease as myelodysplastic syndrome (MDS). The purpose of this study was to determine the prevalence of mutated K-ras oncogene in 30 patients suffering of myelodysplastic..
- Deviated Nasal Septum and its management. A Straight Nasal Septum is rather rare
Abstract : This article discusses various causes of deviation of nasal septum. Â A review of literature suggests that a midline septum is rather rare. Â A midline nasal septum could actually be a clinical curios..
- Global Climate Change: Implications for Public Health in Developing Countries
Abstract: This study looks at the relationship between the effects of changes in the environment and public health, with a particular focus on global warming and developing countries. Through this, the current effects of climate change are explored and with projections of the situation exacerbating in the future, an analysis int..
- Corneal Collagen Cross Linking in Keratoconus
Introduction: Keratoconus is a non-inflammatory degenerative acquired condition affecting the shape of the cornea. The cornea begins to protrude like a cone and this eventually results in distortion, apical thinning and scarring (1). Keratoconus usually begins during puberty and progresses through adolescence and beyond (3). It may..
- Socio-Demographic Characteristics of Clients of Female Sex Workers and their Perspectives, Behaviors and Attitude on HIV and AIDS in Pokhara Valley: A Necessary Enquiry
Abstract : The current situation of HIV in Nepal is different from when the first case was diagnosed in 1988. Till date (2009) total positive cases reported are 14787 out of which 13005 are receiving HIV care. There are gaps and challenges to be addressed in the fight against HIV and AIDS. In this context, clients of Female Sex ..
- The effectiveness of Knowledge Management in the Map of Medicine compared with Nonaka's Knowledge Spiral
Abstract : Recently, the business world has reaped the benefits of an effective Knowledge Management (KM) set up. It has helped propel them into an age of information and this has quickly transformed itself into commercial assets. The importance of integrating this attitude, from the aspect of the medical world, can potentially b..
- Emerging and Re-emerging Infectious Diseases: Hepatitis C
Abstract : Aim: To explore new developments in anti-viral therapy used to treat hepatitis C.Background: Hepatitis C is a blood-borne virus currently affecting 175 million people worldwide. Infection with the virus can predispose to chronic infection, cirrhosis and hepatocellular carcinoma. The virus can be contracted through expo..
- Vascular Risk Factors in Left Colon Anastomosis Leakage: A Computed Tomography Guided Study
Abstract : 25 cases of left colon anastomosis, complicated by an early post-operative leakage, have been studied by Computed Tomography (CT): in 20 of them an arterial vascular insufficiency was observed, and co..
- How have the Changes to the Out of Hours (OOH) Primary Care provision brought about by the 2004 GP contract affected patient safety?
Abstract : The GP contract was changed in 2004. One of these major changes was the Out of Hours system, where GPs had the option to opt out of providing Out of Hours care to patients and shifted this Out of Hours Care responsibility to PCTs. A new model of Out of Hours healthcare was proposed by the Carson review, this was suppos..
- Positive and Negative Effect and Bipolar Disorder. Are the Psychosocial Therapies: Cognitive Behavioural Therapy, Family Focused Therapy and Group Psychoeducation in Adjunction with Pharmacotherapy Effective in the Management of Relapses of Manic and Depressive Episodes in Bipolar Disorder?
Abstract : AimAre the psychosocial therapies: Cognitive Behavioural Therapy, Family Focused Therapy and group psychoeducation in adjunction with pharmacotherapy effective, in the management of relapses of manic and depressive episodes in Bipolar Disorder?MethodThree studies were selected to assess the effectiveness on the followi..
- Statistical Methods for Modeling HIV/AIDS in India
Abstract : Deterministic, Stochastic, Statistical and State space models are the statistical models for forecasting  HIV/ AIDS data. There are also uncertainties associated with these approaches. In addition to this the recent advance in this field used is curve fitting models. Sathian B and Sreedharan J used this method for f..
- Huge rhinolith nasal cavity an interesting case report and a review of literature
Abstract : Rhinoliths are calcareous deposits (stone like) inside the nasal cavity. These stone like structures are highly friable and may crumble when crushed. This interesting case report discusses a patient w..
- The Role of Calcium and Pro-Inflammatory Mediators in Acute Pancreatitis
Abstract: Acute pancreatitis is a common condition that is potentially fatal in severe cases. Pancreatic acinar cell injury in acute pancreatitis results in inflammation. This causes a variety of systemic complications including organ damage, fat necrosis and vascular damage. Many aetiological factors responsible for causing acu..
- Meaning of p-value in Medical Research
Abstract : Any researcher begins the research with null hypothesis and alternative hypothesis. Null will be for supporting the old fact and alternative will be for the new fact invented/ doubted by the researcher/ scientist. Next step is to select one of this scientifically by using the science of statistics. For that the researc..
- Antibacterial activity of essential oils of Seseli indicum a wild weed of family Apiaceae
Abstract: The antibacterial activity of essential oils and their derivatives has been recognized for a long time. In the present study, the antibacterial properties of the essential oils obtained from the seeds of Seseli indicum, of Apiaceae family a wild weed found in the flood prone area of river Tapti, Gorakhpur (India). The ..
- Importance of Biostatistics to Improve the Quality of Medical Journals
Abstract : Most of the Medical journals are facing the methodological rigor problem. A p value of <0.05 means that this result would have arisen by chance on less than five occasion in 100. The confidence interval around a result in a clinical trial indicates the limits within which the “real” difference between th..
- Blow Out Fracture Orbit Endoscopic Reduction a Novel Management Modality
Abstract : Blow out fracture of orbit involves fracture of orbital floor without fracture of infraorbital rim. This injury is common from frontal blow to orbit. Frontal blow to orbit causes increased intraorbita..
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