Submited on: 17 Oct 2011 04:46:23 AM GMT
Published on: 17 Oct 2011 10:39:40 AM GMT
 

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? No
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    Review on

    Teaching medical students to use antibiotics rationally in a medical school in Nepal by

    Shankar R , Bajracharya O , Jha N , Gurung S B, Singh K K  published in WebmedCentral: Education in Medicine Journal as  Case Report in October 2011.

    Reviewed by

    Piryani RM, Piryani Suneel

    KIST Medical College

    r_piryani@yahoo.com

    ………………………………………………………………………………………………………………………………………………..

    It is a disturbing fact that antibiotics are not being used rationally in most of the countries of South Asia including Nepal as these are among the commonly prescribed drugs to treat viral infections like diarrhea, common cold and viral fever which are most of the time self limiting diseases. Antibiotic resistance has recently been recognized as a major problem globally. It has been increasing in Nepal; the main reasons could be inappropriate use by healthcare professionals, besides over the counter sale, limited awareness of the community etc. Rational use of medication is rarely being taught in medical schools of South Asia. This very important aspect of pharmacotherapy is overlooked.      

     

    The article ‘Teaching medical students to use antibiotics rationally in a medical school in Nepal’ written by Shankar R , Bajracharya O , Jha N , Gurung S B, Singh K K enlightens the reader about many important issues like antibiotic resistance, rational use of antibiotics and teaching medical students about rational use of antibiotics.

     

    Teaching medical students about rational use of medication including antibiotics has been neglected for many decades but has received some attention in the last decade with the focus of World Health Organization (WHO) and International Network for the Rational Use of Drugs (INRUD).

     

    The authors approach to use Problem-based learning (PBL) method to teach rational use of medication including antibiotics is practical and draw student attention to real life situations.    

     

    The topics covered in module- essential medicines, P-drug selection, understanding social issues in use of medicines, understanding and responding to pharmaceutical promotion, using independent sources of medicine information, using antibiotics rationally, analyzing prescribing using WHO/INRUD indicators, communicating with a simulated patient, reporting adverse drug reactions, pharmaceutical calculations with innovative methods of teaching will make the  incoming generation of doctors more practical. 

     

    Authors have given conclusion after introduction and covered many thing in introduction, if would have been mentioned under other headings or subheadings will be easy for understanding of common reader.

     

    The authors’ initiative to teach rational use of antibiotics to undergraduate medical students in pre-clinical years and planning for teaching in clinical years is praiseworthy and commendable. This will help in convincing incoming generations of doctors to use antibiotics and other medication judiciously and decreasing acquired antibiotic resistance.    

     

    References

    1.Kansakar P, Baral P, Malla S, Ghimire GR. Antimicrobial susceptibilities of enteric bacterial pathogens isolated in  Kathmandu, Nepal, during 2002-2004. J Infect Dev Ctries. 2011;5(3):163-8.

    2.Sharma DR, Pradhan B, Mishra SK. Multiple drug resistance in bacterial isolates from liquid wastes generated in central hospitals of Nepal. Kathmandu Univ Med J (KUMJ). 2010;8:40-4.

    3.Richir MC, Tichelaar J, Stanm F, Thijs A, Danner SA, Schneider AJ, de Vries TP. A context-learning pharmacotherapy program for preclinical medical students leads to more rational drug prescribing during

    their clinical clerkship in internal medicine. Clin Pharmacol Ther. 2008;84:513-6.

    4. Shankar PR, Jha N, Bajracharya O, Shrestha R, Thapa HS. Teaching Pharmacology at a Nepalese Medical School: The Student Perspective.Australasian Medical Journal 2010; 1:14-22.

    5.Joshi MP, Jayawickramarajah PT. A problem-orientated pharmacotherapy package for undergraduate medical students. Med Teach. 1996;18:75–6.

     

     

  • Competing interests:
    No
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    Yes
  • References:
    References: 1. Book review: Essential Drugs Practical Guidelines 2010 Edition Australasian Medical Journal [AMJ 2011, 4, 7, 410-411] 2. Restricting the use of the FDC of ampicillin /amoxicillin and cloxacillin in a Nepalese teaching hospital. Journal of Clinical and Diagnostic Research 2011 February; (4): xx 3. Academic Detailing-Review article Kathmandu University Medical Journal (2010), Vol. 8, No. 1, Issue 29, 126-134 4.. Learning to maintain a ‘proper’ relationship with the pharmaceutical industry. Letter to the editor Medical Teacher 2010; 32: 181–185 5. Addressing challenges to promoting the more rational use of medicines in teaching hospitals in Nepal. The Journal of Medicine Use in Developing Countries 2009; 1(3):xx 6. Spreading Pharmacovigilance Awareness in a Medical School in Nepal- Letter to Editor Journal of Pharmacy Practice and Research Volume 39, No. 3, 2009 7. Conducting Problem-Stimulated learning in a Nepalese Medical School. Journal of clinical and Diagnostic Research, 2009 Aug: (3) 1709-1712 8. Impact of Medicine & Therapeutic Committee at a new medical college at Nepal- letter to Editor- Journal of Pharmacy Practice and Research Volume 39, No. 2, 2009. 9. Framing objective criteria for selection of medicines in a Nepalese teaching hospital: Initial experiences. J Clin Diag Res 2009; 3: 1455-9. 10. Establishing and strengthening a medicine and therapeutics committee in a medical college in Nepal: initial experience. Pharm World Sci published online: 05 December 2008
  • Experience and credentials in the specific area of science:

    I am coauthor with principle author in some of article related to same subject. Principle author and myself has established Medicine and Therapeutic Committee (MTC) in KIST Medical College, one of the objectives of MTC is to promote rational use of medication in the teaching hospital. I was also facilitator on conducting sessions on pharmaceutical promtion module for second year MBBS students in year 2011. 

  • How to cite:  Piryani R M.Promoting rational use of antibiotics by educating under graduate medical students[Review of the article 'Teaching Medical Students to use Antibiotics Rationally in a Medical School in Nepal ' by Singh K].WebmedCentral 2011;2(10):WMCRW001060
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Partly
3 Is this a new and original contribution? No
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? Yes
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    Teaching versus unethical marketing in rational antibiotic use implementation: review and comment

    The article by Shankar et al. (2011) stressed on their experience in teaching Pharmacology using a problem based approach in the area of rational antibiotic use. Various aspects that were addressed i.e. “learning to use essential medicines rationally, the Personal or P-drug selection process, Understanding social issues in use of medicines, Understanding and responding to pharmaceutical promotion, Using independent sources of medicine information, Using antibiotics rationally, Analyzing prescribing using World Health Organization (WHO)/International Network for the Rational Use of Drugs (INRUD) indicators, Communicating with a simulated patient, Reporting adverse drug reactions (ADRs) and carrying out simple calculations in pharmacology”, were really of great importance. Moreover, examples of scenarios are also provided [1].

     

    Moreover, the aspect of “understanding and responding to pharmaceutical promotion” [1] is very important, though unethical marketing may interfere with the implementation of rational antibiotic use, when the students have graduated and work as a doctor. It is a public secret that unethical marketing may affect prescribing, more than doctors realize [2], as well as affecting professional behavior, and even malpractice, [2-5] and therefore should be addressed in education, as well as policy [3].

     

    Further, the aspect of “using independent sources of medicine information” [1] should be emphasized as Pharmaceutical company acquired research funding may influence the outcome of research [2].

     

    However, the article did not describe the results of practical assessment s and did not analyze the result of this teaching method to know whether the method was successful in the theoretical implementation of rational antibiotic use by students. It was stated that “The practical assessment in pharmacology at the institution has been described in a recent article,” but the cited article only described the methods use in practical assessment without describing the results [6]. Even though, student feedback about the module that was published in another article has been positive, the validity and reliability of the questions in the questionnaire to measure the rational antibiotic use was not analyzed [7]. Moreover, the positive feedback may be due to the inclination of students during the basic science years to prefer studying clinical related sciences that make them feel as playing a doctor.

     

    Finally, testing the results in the prescriptions of the graduates will provide a very valuable data on irrational antibiotic prescription and malpractice, to show whether appropriate teaching and learning method can compete with certain pharmaceutical company unethical marketing.

     

    In conclusion, it will be better if information concerning the results of practical assessment is provided, and future study to obtain data on prescriptions and malpractice of the graduates will be conducted.

     

    References

    1.

    Shankar R , Bajracharya O , Jha N , Gurung S B, Singh K K. Teaching medical students to use antibiotics rationally in a medical school in Nepal . WebmedCentral: Education in Medicine Journal 2011;2(10):WMC002329

    2.

    Norris P, Herxheimer A, Lexchin J, Mansfield P. Drug promotion.

    What we know, what we have yet to learn. Reviews of materials in the WHO/HAI database on drug promotion. Amsterdam: World Health Organization and Health Action International; 2005.

    3.

    Wazana A. Physicians and the pharmaceutical industry.

    Is a gift ever just a gift? JAMA. 2000;283: 373-80.

    4.

    Cousins C. Pharmaceutical marketing: The unethical reform of an industry. Gatton Student Research Publication 2009; 1(2):1-8.

    5.

    Van Zee A. The promotion and marketing of OxyContin: Commercial triumph, public health tragedy. American Journal of Public Health  2009, 99(2): 221-7.

    6.

    Shankar PR, Gurung SB, Jha N, Bajracharya O, Ansari SR, Thapa HS. Practical assessment in pharmacology at a new Nepalese medical school. Journal of Clinical and Diagnostic Research 2010;4:3314-6.

    7.

    Shankar PR, Jha N, Bajracharya O, Shrestha R, Thapa HS. Teaching pharmacology at a Nepalese medical school: The student perspective. Australasian Medical Journal 2010; 1:14-22.

     

  • Competing interests:
    none
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    Yes
  • References:
    1. Pawitan JA. Pembelajaran berdasarkan masalah (problem based learning): haruskah bersamaan dengan integrasi vertical?[Problem based learning: should it be applied with vertical integration?] (Article in Indonesian). J Indones Med Assoc. 2006; 56: 609-13. 2. Pawitan JA, Sukmawati D. Association between presence in lectures and student knowledge gain in problem based learning: experience in Neuropsychiatry module, FMUI,International program. Med J Indones 2009;18(2):131-4. 3. Pawitan JA, Pattiata R. The role of assignments in lab activity test results in Histology. South East Asian Journal of Medical Education 2010;4(2):41-3. 4. Adiwinata Pawitan J.The relevance of problem based process assessment scoring. (comment and review of the article: Initial Experiences of Developing an Assessment Scheme for Problem Based Learning Module in an Undergraduate Preclinical Curriculum)[Review of the article 'Initial Experiences Of Developing An Assessment Scheme For Problem Based Learning Module In An Undergraduate Preclinical Curriculum ' by Shobha KL, Pallath V ].WebmedCentral 2011;2(1):WMCRW00391. 5. Adiwinata Pawitan J.Student motivation is very important in medical education: review and comment[Review of the article ‘Physical Medicine & Rehabilitation Residents Teaching Clinical Anatomy In The Gross Anatomy Lab: Enhanced Student Performance ‘ by Foye P M, Vasan N S, Holland B K].WebmedCentral 2011;2(1):WMCRW00422. 6. Adiwinata Pawitan J.Student motivation and seriousness are important prerequisites for in Just in Time Teaching (JiTT): comment and review[Review of the article ‘Learning Via Just – In- Time (JiTT) Education: A Must For All Medical Schools In The Global Information Age. ‘ by Kanagasabai S , Najimudeen M , De S].WebmedCentral 2011;2(2):WMCRW00477.
  • Experience and credentials in the specific area of science:

    I am involved in developing of modules for problem based learning, resource person, lecturer and facilitator in PBL in the Fac. of Medicine Univ. of Indonesia, and also doing research in Medical education.

  • How to cite:  Adiwinata Pawitan J .Teaching versus unethical marketing in rational antibiotic use implementation: review and comment[Review of the article 'Teaching Medical Students to use Antibiotics Rationally in a Medical School in Nepal ' by Singh K].WebmedCentral 2011;2(10):WMCRW001031
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    3. There are similar studies conducted in other medical schools

    6. I think there is adequate information which is applicable at any Medical school

    Such studies do help students to learn antibiotic prescribing,but then how much is used in their daily practise remains a query,because once the student becomes a intern(internship) they usually prescribe the drugs suggested by the consultant.

    The aim of such studies are really good,but implementing this in really life situations does not happen most of the time.

  • Competing interests:
    NO
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    Professor of pharmacology,Co-ordinator of pharmacovigilance and Convenor of Medical Education Unit

    In our pharmacology practicals we teaching students to choose the antibiotics based on the culture sensitivity report and cost and discuss in detail the P drug selection

  • How to cite:  N S .Teaching medical students to use antibiotics rationally in a medical school in Nepal[Review of the article 'Teaching Medical Students to use Antibiotics Rationally in a Medical School in Nepal ' by Singh K].WebmedCentral 2011;2(10):WMCRW001024
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Review
Posted by Mr. Krishna Kumar Govindarajan on 18 Oct 2011 10:07:44 AM GMT

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? No
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? Yes
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    A good review article summarising the rationale of antibiotic usage. It would be reasonable to expand the same to include all drug prescriptions. The article may perhaps be classified under review article / expert review rather than as case report.

  • Competing interests:
    No
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    This is essentially a day-to-day practical issue when I do rounds, see patients in the clinic and write orders after surgery.

  • How to cite:  Govindarajan K .Review[Review of the article 'Teaching Medical Students to use Antibiotics Rationally in a Medical School in Nepal ' by Singh K].WebmedCentral 2011;2(10):WMCRW001022
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1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? No
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    Good paper! Specially for developing countries.

  • Competing interests:
    no
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    I am professor of dermatology and always find problems similarly of these described.

  • How to cite:  Bedin V .Teaching mediocal students to use antibiotics rationally in a medcial school in Nepal[Review of the article 'Teaching Medical Students to use Antibiotics Rationally in a Medical School in Nepal ' by Singh K].WebmedCentral 2011;2(10):WMCRW001020
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Review by Dr Huw Morgan
Posted by Dr. Huw Morgan on 17 Oct 2011 11:18:40 AM GMT

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    This is a despcriptive rather than research based article but is a good description of an important area of medical education that deserves wide circulation. It give a comprehensive account of how rational antibiotic prescribing is taught in a new medical school in Nepal using appropriate guidelines and interactive teaching techniques.

    In my opinion only minor corrections to the English grammar are needed to improve it.

  • Competing interests:
    No
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    As a General Practitioner I have to be continuously aware of local antibiotic prescribing guidelines in order to avoid contributing to resistance development. As a medical educator I have to consider how to best teach young doctors how to use antibiotics rationally. 

  • How to cite:  Morgan H .Review by Dr Huw Morgan[Review of the article 'Teaching Medical Students to use Antibiotics Rationally in a Medical School in Nepal ' by Singh K].WebmedCentral 2011;2(10):WMCRW001018
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Dear reviewers Thanks for your comments. We have been teaching rational use of antibiotics for three years at KIST Medical College right from the first batch of students. The submission was intended for the innovations section of 'Education in Medicine' journal. However, WebmedCentral did not have the section which caused some confusion. "An outline of the teaching-learning activities conducted by the department of Clinical Pharmacology with the objective of helping medical students use antibiotics rationally was presented as a poster at the First Global forum on bacterial infections held at New Delhi, India from October 3rd to 5th 2011. The first author received a travel grant to attend the conference." We teach students to use all essential medicines rationally and antibiotics have been highlighted as a special class because of their importance and the more serious consequences of misuse. Our article on the ten competencies a medical graduate should develop at the end of practical learning sessions in pharmacology is under review. Regards Dr. Shankar
Responded by Dr. P Ravi Shankar on 19 Oct 2011 07:23:20 AM