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Effect of Combination of Superdisintegrants on Fast Dissolving Tablet of Gliclazide
By Mrs. Rajeshree Panigrahi , Mrs. Saiprasanna Behera , Mr. Prasanta K Choudhury , Dr. K.a. Chowdary , Dr. Gitanjali Mishra
Submited on: 13 Feb 2012 10:07:24 AM GMT
Published on: 13 Feb 2012 12:43:05 PM GMT
 
assessment of submitted review
Posted by Dr. Oliver Grundmann on 13 Apr 2012 09:26:08 PM GMT

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? No
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? No
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? Yes
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? No
9 Are the illustrations and tables necessary and acceptable? No
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    The original research paper on different formulations of the drug gliclazide showed that there are two formulations that have a good release profile for a fast-dissolving tablet over 30 minutes. However, the authors mentioned in the conclusions that formulations C5 and C8 presented with the best dissolution profile but then referred to preparations C4 and C8 in all of the graphs. This may be a simple labeling error but should definitely be corrected. Furthermore, the authors should carefully read over the manuscript and make any necessary diction corrections.

  • Competing interests:
    No competing interests to declare.
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    Pharmacist

  • How to cite:  Grundmann O .assessment of submitted review[Review of the article 'Effect of Combination of Superdisintegrants on Fast Dissolving Tablet of Gliclazide ' by Mishra G].WebmedCentral 2012;3(4):WMCRW001682
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good article
Posted by Mr. Sudeep Patra on 28 Feb 2012 10:13:11 AM GMT

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    it is a very informative study.further study can be done in same categories of drugs.

  • Competing interests:
    no
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    i have envolved in clinical trial of diffrent tye of formulation of antidiabetic drugs regarding their safety and efficacy.

  • How to cite:  Patra S .good article[Review of the article 'Effect of Combination of Superdisintegrants on Fast Dissolving Tablet of Gliclazide ' by Mishra G].WebmedCentral 2012;3(2):WMCRW001522
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Effect of Combination of Superdisintegrants on Fast Dissolving Tablet of Gliclazide
Posted by Mr. Prasanta K Choudhury on 20 Feb 2012 08:11:47 PM GMT

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? Yes
7 Can you suggest any reductions in the paper, or deletions of parts? Yes
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    In the present investigationj use of combination superdisintegrants for better release rate of drug from fast disolving tablets of Gliclazide is one of the novel approach done so far.

    As Glicalazide is poorly soluble drug it needs enhanced solubility in body fluid (in vivo), hence the approach decided by the author is one of the way to enhance the solubility and improvment of drug dissolution.

     

    Here the author suggested to use rational combinations of disintegrants in appropriate proportions  for futher studies.

  • Competing interests:
    No
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    5 years

  • How to cite:  Choudhury P K.Effect of Combination of Superdisintegrants on Fast Dissolving Tablet of Gliclazide[Review of the article 'Effect of Combination of Superdisintegrants on Fast Dissolving Tablet of Gliclazide ' by Mishra G].WebmedCentral 2012;3(2):WMCRW001510
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Effect of Combination of Superdisintegrants on Fast Dissolving Tablet of Gliclazide
Posted by Dr. Manas Bhowmik on 15 Feb 2012 10:32:05 AM GMT

1 Is the subject of the article within the scope of the subject category? Yes
2 Are the interpretations / conclusions sound and justified by the data? Yes
3 Is this a new and original contribution? Yes
4 Does this paper exemplify an awareness of other research on the topic? Yes
5 Are structure and length satisfactory? Yes
6 Can you suggest brief additions or amendments or an introductory statement that will increase the value of this paper for an international audience? No
7 Can you suggest any reductions in the paper, or deletions of parts? No
8 Is the quality of the diction satisfactory? Yes
9 Are the illustrations and tables necessary and acceptable? Yes
10 Are the references adequate and are they all necessary? Yes
11 Are the keywords and abstract or summary informative? Yes
  • Other Comments:

    the article may be published in the present form.

  • Competing interests:
    no
  • Invited by the author to review this article? :
    Yes
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    7 Years of research experiences in the field of formulation development and some studies on different activity of natural products

  • How to cite:  Bhowmik M .Effect of Combination of Superdisintegrants on Fast Dissolving Tablet of Gliclazide [Review of the article 'Effect of Combination of Superdisintegrants on Fast Dissolving Tablet of Gliclazide ' by Mishra G].WebmedCentral 2012;3(2):WMCRW001489
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