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The Human Folate Receptor 1 Gene: Molecular Diagnostic of Folate Deficiency
By Dr. Khue V Nguyen , Dr. Remi Nguyen , Dr. William L Nyhan
Submited on: 08 Jun 2012 02:31:43 AM GMT
Published on: 09 Jun 2012 04:06:13 PM GMT
 
The Human Folate Receptor 1 Gene: Molecular Diagnostic of Folate Deficiency
Posted by Prof. Valcinir Bedin on 10 Jun 2012 08:39:55 PM GMT

  • What are the main claims of the paper and how important are they?

    The main claim was the use of molecular medicine to try to resolve a very important problem.


  • Are these claims novel? If not, please specify papers that weaken the claims to the originality of this one.

    Yes


  • Are the claims properly placed in the context of the previous literature?

    Yes


  • Do the results support the claims? If not, what other evidence is required?

    Yes


  • If a protocol is provided, for example for a randomized controlled trial, are there any important deviations from it? If so, have the authors explained adequately why the deviations occurred?

    The material and methods were fair enough.


  • Is the methodology valid? Does the paper offer enough details of its methodology that its experiments or its analyses could be reproduced?

    Yes and yes


  • Would any other experiments or additional information improve the paper? How much better would the paper be if this extra work was done, and how difficult would such work be to do, or to provide?

    I don`t think additonal information would improve the paper.


  • Is this paper outstanding in its discipline? (For example, would you like to see this work presented in a seminar at your hospital or university? Do you feel these results need to be incorporated in your next general lecture on the subject?) If yes, what makes it outstanding? If not, why not?

    Yes because it reveals an important way to approach an old problem.


  • Other Comments:

    No

  • Competing interests:
    no
  • Invited by the author to review this article? :
    No
  • Have you previously published on this or a similar topic?:
    No
  • References:
    None
  • Experience and credentials in the specific area of science:

    I am a dematologist and nutrologist and professor of medicine.

  • How to cite:  Bedin V .The Human Folate Receptor 1 Gene: Molecular Diagnostic of Folate Deficiency[Review of the article ' The Human Folate Receptor 1 Gene: Molecular Diagnostic of Folate Deficiency ' by Nyhan W].WebmedCentral 2012;3(6):WMCRW001903
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