View All Articles
Displaying 51-100 of 966
- Traditional Systems of Medicine- Now & Forever
Introduction: India has a rich heritage of traditional medicine and the traditional health care system have been flourishing for many centuries. traditional medicine, defined by the WHO as "medical knowledge systems that developed over generations within various societies before the era of modern medicine, including the health pract..
- Hypertrophied Lingual Tonsil an Interesting Case Report and A Review of Literature
Abstract : This interesting case report discusses a case of hypertrophied lingual tonsil. Commonest cause of lingual tonsil hypertrophy is compensatory enlargement following tonsillectomy, next comes GERD which ..
- A Ruptured Old Ectopic Pregnancy that was Suspicious for Tumor
Case : A 40-year-old woman was admitted for melena that she’d experienced for 2 days. For the laboratory findings, the lactate dehydrogenase (LDH) (610) and cancer antigen (CA) 125 (326.7) were increased, ..
- Malignancy After Lung Transplantation: A Literature Review
Abstract : Background: Over the past two decades there have been significant improvements in the quality of life and long-term survival of lung transplant patients. Nevertheless, it has been noted that a number of malignancies have developed in lung-transplant recipients pursuant to lung transplantations. It is therefore importan..
- Hox Homeotic Selector Genes: Key Regulators of Embryogenesis
Abstract: The Hox genes are major regulators of the animal bodyplan. They determine the identities of sequential zones along the main body axis. The Hox genes show collinearity– spatial and temporal ordering of their expression corresponding to their genomic order- a spectacular phenomenon that has excited life scientists sinc..
- Splenic Rupture and Colonoscopy: Case Report and Review of Literature
Abstract : Colonoscopy is a very usually diagnostic and therapeutic procedure in the diagnostic of colonic diseases. Most of the time it is secure procedure but complications can occur: hemorrhages (1.8-2.5%) an..
- Association of Dermatoses with Diabetes- A Case Control Study
Abstract : Diabetes Mellitus (DM) is a metabolic disorder and fifth leading cause of mortality in the world. Diabetes mellitus affects many organ systems of the body including skin. Changes found in skin are largely parallel to those occurring in the internal organs.Aim: The aim of our study was to determine the spectrum of derma..
- CD4 Count: A Monitoring Tool in HIV
Abstract : Background and objectives: Mucocutaneous manifestations are extremely common and varied in HIV infected patients. Their frequencies, pattern and associated factors have been shown to vary from region to region. The present study was done to know the overall prevalence of mucocutaneous manifestations and their relations..
- Hypomelanosis of Ito: An Unusual Association
Abstract : Hypomelanosis of Ito is a neurocutaneous syndrome characterized by hypopigmented lesions occurring in streaks and whorls located on the trunk, head or extremities. Associated abnormalities occur in mu..
- Cystic Fibrosis Otolaryngologist Perspective
Abstract : Cystic fibrosis is an autosomal recessive disorder affecting the exocrine glands. It causes the secretions from these glands to become thick and viscous. There is a tendency to involve multiple organ ..
- Tuning Fork Tests
Abstract : This article reviews the history of tuning fork tests, its current status as a clinical examination tool. All the commonly performed tuning fork tests are discussed in detail. The three commonly perfo..
- A Descriptive Cross Sectional Study to Determine Mucocutaneous Manifestations in Chronic Renal Failure on Hemodialysis
Abstract : Background: Cutaneous involvement in chronic renal failure (CRF) is characterized by a diversity of manifestations. Hemodialysis in CRF improves the quality of life and prolongs the life expectancy of the patients, giving time for newer cutaneous manifestations to develop which are becoming more common.Aim: The aim of ..
- Comparison of Thrombin Generation Assay (TGA) and Non-Activated Partial Thromboplastin Time (NAPTT) for the Assessment of Enhanced Procoagulant Activity in Immunoglobulin Solutions
Abstract: The recent revision of the European Pharmacopoeia stipulates that all intravenous immunoglobulin solutions must be investigated with respect to procoagulant activity. Accordingly, the manufacturing processes must be validated regarding the removal of such compounds, to ensure a minimized thromboembolic risk for patient.. - The Germ-soma Conflict Theory of Aging and Death: Obituary to the "Evolutionary Theories of Aging"
Abstract: Regarding aging, the scientific community persists in a state of collective schizophrenia. This state is owed to the so-called “evolutionary theories of aging”. According to these theories, aging, following the peri-/postreproductive decline of selection pressure, is posited to be haphazard, not selected fo..
- Rhinosporidiosis Personal Experience and Review of Literature
Abstract : Rhinosporidiosis has been defined as a chronic granulomatous disease characterised by production of polyps and other manifestations of hyperplasia of nasal mucosa. The etiological agent is Rhinosporid..
- Carhart's Notch Its Implications
Abstract : Carhart’s notch is classically seen as a dip centered around 2 kHz range of bone conduction curve audiometery. This feature is seen in patients with otosclerosis. This article attempts to discus..
- Novel Use of Tissue Glue in Repair of Rent in Thyrohyoid Membrane After Excision of External Laryngocele
Abstract : This paper narrates our experience of using tissue glue to seal the rent in thyrohyoid membrane following excision of external laryngocele. Thyrohyoid membrane is highly elastic, and this elasticity m..
- Treating Cancer with Vaccine
Abstract : One of the most common causes of death is cancer. The traditional cancer treatments are rarely curative for disseminated cancers. Lately another approach in cancer therapy has been proposed – immunotherapy with cancer vaccines. In this review article we discuss different types of cancer vaccine, which include vir..
- Premature Ovarian Failure After Uterine Artery Embolization
Abstract : Uterine artery embolization (UAE) is popular in some countries for management of postpartum hemorrhage, uterine myoma, and adenomyosis. However, avoidance of complications is important to preserve the uterus. The most serious complication is premature ovarian failure. UAE is advantageous for preserving the uterus for f..
- Mucoceles of Paranasal Sinuses
Abstract : Mucoceles are gradually expanding lesion involving paranasal sinuses. This is usually caused due to obstruction to the normal drainage channels of paranasal sinuses leading on to pent up secretions wi..
- Tests for Malingering
Abstract : Malingering is common these days with liberal workmen compensation act. Lots of concessions are given to physically challenged these days. It is our duty to ensure that these incentives reach the deserving. In order to identify the beneficiaries we should weed out malingerers. Fortunately there are various tests which ..
- Irish Hospital Consultant Views on the Management of Hereditary Haemochromatosis and Analysis of the Differences Between 'Common Practice' and The Management Guidelines Available.
Abstract: Background: 0.05% of those with Northern European lineage carry homozygous mutations in the HFE gene causing iron overload. This is a disease with considerable morbidity, which can be screened for. There are many national and regional protocols in place which are somewhat incongruent with each other. We believe that ma..
- Leakage of Colonic Anastomosis: Computed Tomography Diagnosis
Abstract : Postoperative peritonitis following leakage of a colonic anastomosis is a challenging surgical complication, where a prompt clinical diagnosis, sometimes difficult, is requested before any therapeutic..
- Atrophic Rhinitis: A Literature Review
Abstract : Atrophic rhinitis is a chronic embarrassing debilitating disease involving nasal cavity and paranasal sinuses. It is characterized by foul smelling crusts (greenish) inside the nasal cavity. Nasal muc..
- Preventing Nerve Damage During Thyroid Surgeries
Abstract : Thyroid sugery is a potential risk for vital nerves which include recurrent laryngeal nerve and superior laryngeal nerve. Out of these two damage to recurrent laryngeal nerve leaves the patient with a..
- Evaluation of the Role of Patient Video Diaries as a Part of a Professionalism Module for Pre-Clinical Undergraduates
Abstract: Background: In an ideal world we would expect students to favour seeing ‘real patients’ in our workshops but resource constraints may not allow this. We wondered what second year students (N=127) thought about a single station per workshop which allowed them to watch two short patient video diary clips (You-Tube), ..
- Is it Necessary for Adults to Continue a Phenylalanine Strict Diet After Diagnosis of Phenylketonuria During Childhood?
Abstract: Phenylketonuria is an inherited metabolic disorder whereby the sufferers are unable to produce phenylalanine hydroxylase, an enzyme that is required to metabolise the amino acid phenylalanine. If there is a deficiency of this enzyme, phenylalanine levels rise to potentially serious levels which can lead to mental retar..
- Bacterial Contamination in the Kitchen: Could It Be Pathogenic?
Abstract : Background: Food borne infection is a serious health problem that results from improper food preparation or cross-contamination. Cross-contamination is produced by contaminated raw foods during further processing, preparation of food by infected person or due to inadequate cleaning of kitchen. Present study is carried ..
- Effect of Combination of Superdisintegrants on Fast Dissolving Tablet of Gliclazide
Abstract: Objective of this study was to formulate directly compressible fast dissolving tablets of Gliclazide with sufficient mechanical integrity, content uniformity, and acceptable palatability to assist patients of any age group for easy administration and to show the effect of maximum concentration (10 %) of different combi..
- Evaluation of Antioxidant Activity of Ocimum canum Hydro-alcoholic Leaf Extract in the Prevention of Hepatic Ischaemia
Abstract: The aqueous leaf extracts of Ocimum canum (OC) were studied for their antioxidant activity. The in vitro antioxidant models used were DPPH radical scavenging activity, Hydroxyl peroxide radical scavenging method, reducing power assay which proved the plant to be rich in antioxidants. The study was carried out at diffe..
- Review of JAMA article "Laparoscopic Adjustable Gastric Banding in Severely Obese Adolescents" by O'Brien et al
Citation of the Article Reviewed: O'Brien PE, Sawyer SM, Laurie C, Brown WA, Skinner S, Veit F, Paul E, Burton PR, McGrice M, Anderson M, Dixon JB. Laparoscopic adjustable gastric banding in severely obese adolescents: a randomized trial. JAMA 2010; 303(6):519-26...
- The Significance of Margin Involvement in Radical Prostatectomy Specimens for Presumed Localized Adenocarcinoma of Prostate in Relation to PSA (Biochemical) Failure Rate
Abstract: Background: There is no clear cut way of predicting which patients would develop PSA failure after radical prostatectomy for localised prostate cancer.Aims: To investigate the hypothesis that pursuant to radical prostatectomy for localised prostate cancer, surgical margin involvement and non-involvement influence the P..
- Serum PSA, Gleason Score and Clinical Staging in Predicting Biochemical (PSA) Failure After Radical Prostatectomy for Carcinoma of Prostate
Abstract: Background: It has been suggested that pre-operative serum PSA, Gleason Score of the tumour as well as stage of the tumour may predict the possibility of PSA (Biochemical) recurrence after radical prostatectomy for localized prostate cancer. Aims: To investigate and to confirm the relationship between biochemical failu..
- The Potential Usefulness of Pre and Post Operative Risk Group Stratification in Predicting PSA Failure after Radical Prostatectomy for Localised Prostate Cancer
Abstract: Background: There is no clear cut way of predicting exactly prior to radical prostatectomy which patients would subsequently develop Biochemical failure post operatively.Aims: To investigate the usefulness of Risk Group stratification based upon: pre-operative PSA, clinical staging and Gleason score assessment of prost..
- Streptococcus (GAS) as Cause of Necrotizing Fasciitis Associated with Septic Shock and Multiorgan Dysfunction
Abstract : Necrotizing fasciitis is a rare infection caused by microorganisms called “flesh eating bacteria”. It is characterized by rapid tissue destruction along superficial fascia, systemic signs of toxic..
- Bilateral Synchronous Classical Seminoma of Testes with Bilateral Cannon Ball Metastases: A Case Report with a Review of the Literature
Abstract : Background: Synchronous bilateral germ cell tumours of the testis are rare. About 25% of testicular seminomas present with advanced clinical stage disease. Management of bilateral synchronous seminoma may quite often necessitate the performance of bilateral radical orchidectomy which could be associated with psychologi..
- Review of NEJM article, "Bariatric Surgery versus Conventional Medical Therapy for Type 2 Diabetes" by Mingrone et al.
Citation of the Article Reviewed: Mingrone G, Panunzi S, De Gaetano A, et al. Bariatric surgery versus conventional medical therapy for type 2 diabetes. N Engl J Med 2012. DOI: 10.1056/NEJMoa1200111. Available at http://www.nejm.org/doi/full/10.1056/NEJMoa1200111#t=article Last accessed on 08/04/2012..
- Piracetam (2-Oxo-Pyrrolidone) Advance and Modulate Central Processing Reaction Time in Normal Healthy Volunteers: Randomized Experimental Study; Single Blind Clinical Trail
Abstract : The present study was designed to show the effect of piracetam (2-Oxo-Pyrrolidone) on simple reaction time. This study involved 30 healthy volunteers which were recruited from medical college students (20 males and 10 females) .The reaction time was measured by ruler dropper test method, and by this method we can deter..
- Disaster Medicine: Perspective
My opinion: Disaster medicine, as recent events emphasize, is a specialty of growing importance in the field of medicine. The risk of disasters continues to increase due to multiple factors. These factors include global trends such as population growth, urbanization and the globalization of industry. Furthermore, there is an ever..
- Occurrence of Stromal Derived Factor-1 Polymorphism In Kenyan Population
Abstract: Genetic polymorphism in chemokine receptors and coreceptor genes influences susceptibility to HIV-1 infection and disease progression. The mutated Stromal Derived Factor-1 3A`/3A` (SDF-1 3’A) competes with the virus for the coreceptor site Cystein-X-cystein receptor 4 (CXCR4) on the CD4+ T-cells therefore down-regula..
- What are the Effects of Topical N-Acetylcarnosine [eye drops] on Cataract-Inhibited Vision in an Elderly Subject? - A Case Report
Abstract : Introduction: Cataract onset has a limited prognosis presenting a diagnostic and therapeutic challenge. Mild cataract-inhibited vision is typically managed by Doctors of Optometry with prescription eyeglasses to manage clouding of the lens or glare. If cataracts progress, surgical correction may be recommended.Case: A ..
- Observational Study of Chemoprophylaxis with Chloroquine and Doxycycline on Incidence of Malaria in North-East Sector of India
Abstract : Background: Malaria in North-East sector is the most important cause of morbidity and if not treated in time, leads to mortality. Troops are engaged in counter insurgency Ops in this area & deployed all over in the known hyper endemic malaria Zone; notified chloroquine resistant areas both by National Anti Malaria Prog..
- On Possible Primary Biological Function of Cholera Toxin: Interaction with Vibrio Cholerae Biofilms in the Human Intestine during Infection
Abstract: A hypothesis is presented that cholera toxin (CT) secreted by toxigenic Vibrio cholerae O1 El Tor binds V. cholerae cells within biofilms formed in the human intestine during infection and interacts with these cells. Interaction of CT with the cells within a biofilm leads to up-regulation of cellular processes and enha..
- Transient Recurrent Acquired Delayed Eidetic Memory: TRADEM Syndrome-Remembering the Present
Abstract : A seventy eight year old psychiatrist developed recurrent transient episodes of sectoral visual colorful and detailed memories, as the actual identical events that have occurred in real life and registered by him in previous hours, resurrecting the actual original experience in a clear sensorium. He had no additional s..
- Clinical Spectrum of Acute Abdomen in Cape Coast
Abstract : Background: Central Regional Hospital, Cape Coast, Ghana is the main referral center for the region.The hospital has been redesignated a Teaching Hospital to serve as the main teaching base for the School of Medical Sciences, University of Cape Coast.This study was done as part of assessment of the hospital’s emerg..
- Review of NEJM article "Bariatric Surgery versus Intensive Medical Therapy in Obese Patients with Diabetes" by Schauer et al
Citation of the Article Reviewed: Philip R. Schauer, Sangeeta R. Kashyap, Kathy Wolski, Stacy A. Brethauer, John P. Kirwan, Claire E. Pothier,Susan Thomas, Beth Abood, Steven E. Nissen, Deepak L. Bhatt. Bariatric Surgery versus Intensive Medical Therapy in Obese Patients with Diabetes. NEJM 2012 March. Available on http://www.nejm.org/doi/full/10.1056/..
- Caeco-colic Intussusception Simulating an Appendicular Mass
Background: Acute appendicitis is a common diagnosis encountered in emergency surgical admissions with a need for an immediate appendicectomy. In about 2-6% of cases, an appendicular mass has already developed at presentation. (1) There is the trend to treat appendicular mass by conservative management, which may be adequate in ch..
- Painful Movements and Mobility after Urological Surgery: Studying the Feasibility of Pre-operative Exercise, A New Mobility Test and a Randomised Controlled Trial Protocol with Cystectomy Patients in Intensive Care [ISRCTN32898285]
Abstract: Background: Cystectomy and ileal neobladder are standard procedures in bladder cancer treatment. Regaining mobility quickly after surgery, however, is aggravated by the facts that median laparotomy is used to access the abdomen, and that there are severe tissue violations during surgery. These result in post-operative ..
- Identification of a Putative PRDM9-Binding Motif within the Homologous Recombination Hotspot in the SEC1 and FUT2 Genes
Introduction: The FUT2 gene (OMIM #182100) encodes ?(1,2)fucosyltransferase which regulates the expression of the ABO and Lewis histo-blood group antigens via the synthesis of H antigen on epithelial cells. FUT2 and its homologous pseudogene, SEC1, are separated by 23 kb on chromosome 19q13.3. To date, two alleles derived from homol..
- Epidemiological Study of Reproductive Tract Infections in Rural Area of Indore District.
Abstract : Research Question:What is the burden of Reproductive Tract Infections in Women of reproductive age group in rural Indore?Objective:1) To find out the magnitude of problem of RTIs in women aged 15-44 years in villages of Double Chowki PHC of Indore District, Madhya Pradesh.2) To study the epidemiological determinants of..
All site content, except where otherwise noted, is licensed under a